GB2226313B - Capsaicin derivatives - Google Patents

Capsaicin derivatives

Info

Publication number
GB2226313B
GB2226313B GB8928581A GB8928581A GB2226313B GB 2226313 B GB2226313 B GB 2226313B GB 8928581 A GB8928581 A GB 8928581A GB 8928581 A GB8928581 A GB 8928581A GB 2226313 B GB2226313 B GB 2226313B
Authority
GB
United Kingdom
Prior art keywords
capsaicin derivatives
capsaicin
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8928581A
Other languages
English (en)
Other versions
GB8928581D0 (en
GB2226313A (en
Inventor
Derek J Reid
Christopher S J Walpole
Roger Wrigglesworth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Pharmaceuticals UK Ltd
Original Assignee
Sandoz Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888830143A external-priority patent/GB8830143D0/en
Priority claimed from GB898922440A external-priority patent/GB8922440D0/en
Application filed by Sandoz Products Ltd filed Critical Sandoz Products Ltd
Publication of GB8928581D0 publication Critical patent/GB8928581D0/en
Publication of GB2226313A publication Critical patent/GB2226313A/en
Application granted granted Critical
Publication of GB2226313B publication Critical patent/GB2226313B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/06—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms
    • C07C335/10—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C335/12—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton the carbon skeleton containing six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
GB8928581A 1988-12-23 1989-12-19 Capsaicin derivatives Expired - Lifetime GB2226313B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888830143A GB8830143D0 (en) 1988-12-23 1988-12-23 Improvements in or relating to organic compounds
GB898922440A GB8922440D0 (en) 1989-10-05 1989-10-05 Improvements in or relating to organic compounds

Publications (3)

Publication Number Publication Date
GB8928581D0 GB8928581D0 (en) 1990-02-21
GB2226313A GB2226313A (en) 1990-06-27
GB2226313B true GB2226313B (en) 1992-06-03

Family

ID=26294772

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8928581A Expired - Lifetime GB2226313B (en) 1988-12-23 1989-12-19 Capsaicin derivatives

Country Status (23)

Country Link
JP (1) JPH0764803B2 (ja)
AT (1) AT397797B (ja)
AU (1) AU628902B2 (ja)
BE (1) BE1003848A3 (ja)
CA (1) CA2006115A1 (ja)
CH (1) CH678621A5 (ja)
DE (1) DE3942729A1 (ja)
DK (1) DK657089A (ja)
ES (1) ES2021182A6 (ja)
FI (1) FI896192A0 (ja)
FR (1) FR2640971B1 (ja)
GB (1) GB2226313B (ja)
GR (1) GR1000460B (ja)
HU (1) HU206082B (ja)
IE (1) IE59336B1 (ja)
IL (1) IL92830A (ja)
IT (1) IT1237479B (ja)
LU (1) LU87648A1 (ja)
NL (1) NL8903132A (ja)
NZ (1) NZ231965A (ja)
PH (1) PH27571A (ja)
PT (1) PT92674A (ja)
SE (1) SE8904306L (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2058492T3 (es) * 1988-02-03 1994-11-01 Hybritech Inc Mejoras en o relativas a haptenos modificados utiles como agentes terapeuticos y de formacion de imagenes.
HU210683B (en) * 1990-06-18 1995-06-28 Sandoz Ag Process for producing n-benzyl-n1-(phenyl-alkyl)-thiourea derivatives and pharmaceutical compositions containing the same
GB9519270D0 (en) * 1995-09-21 1995-11-22 Sandoz Pharma Uk Organic compounds
GB9711962D0 (en) * 1997-06-10 1997-08-06 Reckitt & Colmann Prod Ltd Therapeutically active compositions
DE10019670A1 (de) * 2000-04-19 2001-10-31 Diego Palermo Heilmittel auf Paprika-Basis und Verwendung desselben
ATE393141T1 (de) * 2000-08-21 2008-05-15 Pacific Corp Neue thiourea-derivate und pharmazeutische zusammensetzungen die diese enthalten
PE20030417A1 (es) 2001-09-13 2003-08-06 Smithkline Beecham Plc Derivados de urea como antagonistas del receptor vainilloide
ES2316777T3 (es) 2002-02-15 2009-04-16 Glaxo Group Limited Moduladores de receptores vainilloides.
GB0319150D0 (en) 2003-08-14 2003-09-17 Glaxo Group Ltd Novel compounds
AT413646B (de) * 2004-04-02 2006-04-15 Hammer Johann Dr Verwendung von capsaicin und/oder capsaicinoiden
US7576099B2 (en) 2005-02-28 2009-08-18 Renovis, Inc. Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
WO2012045729A1 (en) 2010-10-05 2012-04-12 Glaxo Group Limited Imidazo [1, 2 -a] pyridine and pyrazolo [1, 5 -a] pyridine derivatives as trpv1 antagonists
WO2012072512A1 (en) 2010-11-29 2012-06-07 Glaxo Group Limited N-cyclobutyl-imidazopyridine or -pyrazolopyridine carboxamides as trpv1 antagonists
US8754101B2 (en) 2011-04-11 2014-06-17 Glaxo Group Limited N-cyclobutyl-imidazopyridine-methylamine as TRPV1 antagonists
CN111647537B (zh) * 2020-06-18 2022-04-26 浙江工业大学 一种耐盐辣椒素降解菌、应用及餐厨垃圾处理方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU795462A3 (ru) * 1975-03-14 1981-01-07 Эдьт Дьедьесерведьесети Дьяр (Фирма) Способ получени тиокарбамидныхпРОизВОдНыХ
ES474449A1 (es) * 1978-10-23 1979-05-01 Invest Tecnica Aplicada Procedimiento de obtencion de ureas y tioureas con actividad farmacologica.
US4460602A (en) * 1981-06-30 1984-07-17 The Procter & Gamble Company Urea derivatives
ES2061624T3 (es) * 1987-03-09 1994-12-16 Procter & Gamble Compuestos fenilicos sustituidos con amino-etilo en posicion beta, y composiciones anti-inflamatorias o analgesicas que los contienen.
GB8715357D0 (en) * 1987-06-30 1987-08-05 Sandoz Inst For Medical Resear Organic compounds

Also Published As

Publication number Publication date
NZ231965A (en) 1992-09-25
FR2640971B1 (ja) 1994-04-29
HU206082B (en) 1992-08-28
IT8948682A0 (it) 1989-12-21
AU628902B2 (en) 1992-09-24
JPH02231469A (ja) 1990-09-13
SE8904306L (sv) 1991-06-22
PH27571A (en) 1993-08-18
GB8928581D0 (en) 1990-02-21
CH678621A5 (ja) 1991-10-15
IT1237479B (it) 1993-06-07
IL92830A0 (en) 1990-09-17
GB2226313A (en) 1990-06-27
LU87648A1 (fr) 1991-09-18
ATA290289A (de) 1993-11-15
HUT56342A (en) 1991-08-28
ES2021182A6 (es) 1991-10-16
GR890100859A (en) 1991-03-15
FR2640971A1 (ja) 1990-06-29
NL8903132A (nl) 1990-07-16
DE3942729A1 (de) 1990-07-05
GR1000460B (el) 1992-07-30
DK657089D0 (da) 1989-12-21
FI896192A0 (fi) 1989-12-21
AT397797B (de) 1994-06-27
BE1003848A3 (fr) 1992-06-30
IE59336B1 (en) 1994-02-09
DK657089A (da) 1990-06-24
AU4717089A (en) 1990-06-28
IL92830A (en) 1994-12-29
SE8904306D0 (sv) 1989-12-21
IE894151L (en) 1990-06-23
CA2006115A1 (en) 1990-06-23
HU896479D0 (en) 1990-02-28
JPH0764803B2 (ja) 1995-07-12
PT92674A (pt) 1990-06-29

Similar Documents

Publication Publication Date Title
YU222289A (en) Hinuklidin derivatives
GB8905443D0 (en) Dihalogrnobenzene derivatives
GB2226313B (en) Capsaicin derivatives
GB2222828B (en) Butynylamine derivatives
EG19385A (en) N-phenylpyrazol -4-yl-ether derivatives
IL89230A0 (en) Acylphenol derivatives
ZA89860B (en) Pyranobenzoxadiazole derivatives
PH27235A (en) Benzopyranol derivatives
ZA892723B (en) Phosphonoalkylpurine derivatives
GB2222829B (en) Benzylidenecyclanone derivatives
ZA899424B (en) Novel benzopyranylpyrrolinone derivatives
YU200589A (en) Derivatives 3-acyl-2-oxyndol-1-carboxamida
ZA892148B (en) Novel delta4-androstene derivatives
PH27275A (en) Cycloalkylthiazole derivatives
ZA898604B (en) Pyranylethyl-naphthalene derivatives
IL90695A0 (en) Substituted azacyclohexyl derivatives
ZA893169B (en) 3-cyano-4-phenyl-pyrrole derivatives
ZA899582B (en) Benzohydroxymic derivatives
ZA899858B (en) Capsaicin derivatives
GB8826929D0 (en) Amide derivatives
GB8811638D0 (en) Amide derivatives
GB8801962D0 (en) Amide derivatives
FI103406B1 (fi) 3-piperatsinyylibentsatsolijohdannainen
GB8820600D0 (en) Dihalocyclohexanone derivatives
ZA895891B (en) Halogenovinyl-azole derivatives

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19951219