GB2139645A - Antibody to human prostrate cancer - Google Patents
Antibody to human prostrate cancer Download PDFInfo
- Publication number
- GB2139645A GB2139645A GB08408988A GB8408988A GB2139645A GB 2139645 A GB2139645 A GB 2139645A GB 08408988 A GB08408988 A GB 08408988A GB 8408988 A GB8408988 A GB 8408988A GB 2139645 A GB2139645 A GB 2139645A
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- United Kingdom
- Prior art keywords
- antibody
- cell
- hybridoma
- prostate cancer
- human prostate
- Prior art date
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- HOQPTLCRWVZIQZ-UHFFFAOYSA-H bis[[2-(5-hydroxy-4,7-dioxo-1,3,2$l^{2}-dioxaplumbepan-5-yl)acetyl]oxy]lead Chemical compound [Pb+2].[Pb+2].[Pb+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HOQPTLCRWVZIQZ-UHFFFAOYSA-H 0.000 description 1
- OSQPUMRCKZAIOZ-UHFFFAOYSA-N carbon dioxide;ethanol Chemical compound CCO.O=C=O OSQPUMRCKZAIOZ-UHFFFAOYSA-N 0.000 description 1
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- 238000003113 dilution method Methods 0.000 description 1
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
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- AUVVAXYIELKVAI-CKBKHPSWSA-N emetine Chemical compound N1CCC2=CC(OC)=C(OC)C=C2[C@H]1C[C@H]1C[C@H]2C3=CC(OC)=C(OC)C=C3CCN2C[C@@H]1CC AUVVAXYIELKVAI-CKBKHPSWSA-N 0.000 description 1
- 229960002694 emetine Drugs 0.000 description 1
- AUVVAXYIELKVAI-UWBTVBNJSA-N emetine Natural products N1CCC2=CC(OC)=C(OC)C=C2[C@H]1C[C@H]1C[C@H]2C3=CC(OC)=C(OC)C=C3CCN2C[C@H]1CC AUVVAXYIELKVAI-UWBTVBNJSA-N 0.000 description 1
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- MHMNJMPURVTYEJ-UHFFFAOYSA-N fluorescein-5-isothiocyanate Chemical compound O1C(=O)C2=CC(N=C=S)=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 MHMNJMPURVTYEJ-UHFFFAOYSA-N 0.000 description 1
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- KHIWWQKSHDUIBK-UHFFFAOYSA-N periodic acid Chemical compound OI(=O)(=O)=O KHIWWQKSHDUIBK-UHFFFAOYSA-N 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 210000004180 plasmocyte Anatomy 0.000 description 1
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- 229940113116 polyethylene glycol 1000 Drugs 0.000 description 1
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- NGVDGCNFYWLIFO-UHFFFAOYSA-N pyridoxal 5'-phosphate Chemical compound CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O NGVDGCNFYWLIFO-UHFFFAOYSA-N 0.000 description 1
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- 239000007974 sodium acetate buffer Substances 0.000 description 1
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- 239000012279 sodium borohydride Substances 0.000 description 1
- 229910000033 sodium borohydride Inorganic materials 0.000 description 1
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- WGTODYJZXSJIAG-UHFFFAOYSA-N tetramethylrhodamine chloride Chemical compound [Cl-].C=12C=CC(N(C)C)=CC2=[O+]C2=CC(N(C)C)=CC=C2C=1C1=CC=CC=C1C(O)=O WGTODYJZXSJIAG-UHFFFAOYSA-N 0.000 description 1
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- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6191983A JPS59188557A (ja) | 1983-04-08 | 1983-04-08 | ヒト前立腺癌の分類および同定用試薬 |
| JP58061917A JPS59187796A (ja) | 1983-04-08 | 1983-04-08 | 抗ヒト前立腺癌抗体 |
| JP6192283A JPS59186923A (ja) | 1983-04-08 | 1983-04-08 | ヒト前立腺癌治療用薬剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB8408988D0 GB8408988D0 (en) | 1984-05-16 |
| GB2139645A true GB2139645A (en) | 1984-11-14 |
Family
ID=27297684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB08408988A Withdrawn GB2139645A (en) | 1983-04-08 | 1984-04-06 | Antibody to human prostrate cancer |
Country Status (4)
| Country | Link |
|---|---|
| DE (1) | DE3413341A1 (enExample) |
| FR (1) | FR2551085A1 (enExample) |
| GB (1) | GB2139645A (enExample) |
| SE (1) | SE8401946L (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4970299A (en) * | 1986-07-03 | 1990-11-13 | Sloan-Kettering Institute For Cancer Research | Monoclonal antibodies selective for prostate cancer |
| US5055404A (en) * | 1988-08-09 | 1991-10-08 | Masamichi Ueda | Monoclonal antibody specifically reactive to surface of human prostatic epithelial cells |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0067642A1 (en) * | 1981-06-08 | 1982-12-22 | Samuel Dr. Bogoch | Detection of malignant tumor cells |
| EP0073953A2 (en) * | 1981-08-31 | 1983-03-16 | Sloan-Kettering Institute For Cancer Research | Monoclonal antibodies to cell surface antigens of human renal cancer |
| GB2109407A (en) * | 1981-10-27 | 1983-06-02 | Hybritech Inc | Tumour imaging with radiolabelled monoclonal antibodies |
| EP0087898A1 (en) * | 1982-02-22 | 1983-09-07 | Cancer Research Campaign Technology Limited | Antibodies and antigens useful in the diagnosis and treatment of cancer |
| EP0090343A2 (de) * | 1982-03-27 | 1983-10-05 | BEHRINGWERKE Aktiengesellschaft | Zell-Hybrid, Verfahren zu seiner Herstellung sowie seine Verwendung |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1981001849A1 (en) * | 1979-12-28 | 1981-07-09 | Research Corp | Purified human prostate antigen |
-
1984
- 1984-04-06 SE SE8401946A patent/SE8401946L/ not_active Application Discontinuation
- 1984-04-06 GB GB08408988A patent/GB2139645A/en not_active Withdrawn
- 1984-04-09 DE DE19843413341 patent/DE3413341A1/de not_active Withdrawn
- 1984-04-09 FR FR8405576A patent/FR2551085A1/fr active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0067642A1 (en) * | 1981-06-08 | 1982-12-22 | Samuel Dr. Bogoch | Detection of malignant tumor cells |
| EP0073953A2 (en) * | 1981-08-31 | 1983-03-16 | Sloan-Kettering Institute For Cancer Research | Monoclonal antibodies to cell surface antigens of human renal cancer |
| GB2109407A (en) * | 1981-10-27 | 1983-06-02 | Hybritech Inc | Tumour imaging with radiolabelled monoclonal antibodies |
| EP0087898A1 (en) * | 1982-02-22 | 1983-09-07 | Cancer Research Campaign Technology Limited | Antibodies and antigens useful in the diagnosis and treatment of cancer |
| GB2121417A (en) * | 1982-02-22 | 1983-12-21 | Carlton Med Prod | Antigens and antibodies useful in the detection of cancer |
| EP0090343A2 (de) * | 1982-03-27 | 1983-10-05 | BEHRINGWERKE Aktiengesellschaft | Zell-Hybrid, Verfahren zu seiner Herstellung sowie seine Verwendung |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4970299A (en) * | 1986-07-03 | 1990-11-13 | Sloan-Kettering Institute For Cancer Research | Monoclonal antibodies selective for prostate cancer |
| US5055404A (en) * | 1988-08-09 | 1991-10-08 | Masamichi Ueda | Monoclonal antibody specifically reactive to surface of human prostatic epithelial cells |
Also Published As
| Publication number | Publication date |
|---|---|
| SE8401946L (sv) | 1984-11-13 |
| SE8401946D0 (sv) | 1984-04-06 |
| DE3413341A1 (de) | 1984-11-22 |
| FR2551085A1 (enExample) | 1985-03-01 |
| GB8408988D0 (en) | 1984-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |