GB2102412B - Proline derivatives and process for producing the same - Google Patents

Proline derivatives and process for producing the same

Info

Publication number
GB2102412B
GB2102412B GB08215345A GB8215345A GB2102412B GB 2102412 B GB2102412 B GB 2102412B GB 08215345 A GB08215345 A GB 08215345A GB 8215345 A GB8215345 A GB 8215345A GB 2102412 B GB2102412 B GB 2102412B
Authority
GB
United Kingdom
Prior art keywords
producing
same
proline derivatives
proline
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08215345A
Other languages
English (en)
Other versions
GB2102412A (en
Inventor
Sadao Tanaka
Kiyonori Kuromaru
Yasuo Fujimura
Tomoyasu Iwaoka
Isao Matsunaga
Junichiro Aono
Noriko Obatake
Hideki Nakano
Yoshikazu Hinohara
Masafumi Fukushima
Hiroyuki Nabata
Shun-Ichi Hata
Kazushige Sakai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP56094002A external-priority patent/JPS57209270A/ja
Priority claimed from JP56137823A external-priority patent/JPS5839661A/ja
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of GB2102412A publication Critical patent/GB2102412A/en
Application granted granted Critical
Publication of GB2102412B publication Critical patent/GB2102412B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB08215345A 1981-06-19 1982-05-26 Proline derivatives and process for producing the same Expired GB2102412B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP56094002A JPS57209270A (en) 1981-06-19 1981-06-19 Proline derivative
JP56137823A JPS5839661A (ja) 1981-09-03 1981-09-03 プロリン誘導体の製法

Publications (2)

Publication Number Publication Date
GB2102412A GB2102412A (en) 1983-02-02
GB2102412B true GB2102412B (en) 1985-01-09

Family

ID=26435270

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08215345A Expired GB2102412B (en) 1981-06-19 1982-05-26 Proline derivatives and process for producing the same

Country Status (19)

Country Link
KR (1) KR890000769B1 (es)
AT (1) AT377496B (es)
CA (1) CA1235120A (es)
CH (1) CH651825A5 (es)
DE (1) DE3222779A1 (es)
DK (1) DK156054C (es)
ES (2) ES8307216A1 (es)
FI (1) FI75804C (es)
FR (1) FR2508040B1 (es)
GB (1) GB2102412B (es)
HU (1) HU188177B (es)
IL (1) IL65954A (es)
IT (1) IT1157053B (es)
MX (2) MX155724A (es)
NL (1) NL193282C (es)
NO (1) NO156408C (es)
PT (1) PT75076B (es)
SE (1) SE453595B (es)
SU (1) SU1316556A3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6354321A (ja) * 1985-03-27 1988-03-08 Ajinomoto Co Inc 血糖降下剤
KR870007114A (ko) * 1986-01-21 1987-08-14 우에노 기미오 티올 에스테르 유도체의 안정된 고형제
ZA896851B (en) 1988-09-14 1990-06-27 Hoffmann La Roche Use of ace-inhibitors
DE59409631D1 (de) * 1993-07-15 2001-02-15 Hoffmann La Roche Pharmazeutische Kombination, die einen Hemmer des Renin-Angiotensin-Systems und einen Endothelin-Antagonisten enthält

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA802420B (en) * 1979-05-18 1981-04-29 Squibb & Sons Inc Aminoacyl derivatives of mercaptoacyl amino acids

Also Published As

Publication number Publication date
FI75804C (fi) 1988-08-08
DE3222779A1 (de) 1983-01-27
DK273082A (da) 1982-12-20
NO156408B (no) 1987-06-09
IL65954A (en) 1986-03-31
CH651825A5 (de) 1985-10-15
MX171888B (es) 1993-11-23
ES513277A0 (es) 1983-07-01
KR840000488A (ko) 1984-02-22
NL193282B (nl) 1999-01-04
PT75076B (en) 1984-05-09
ES8307216A1 (es) 1983-07-01
FI822171A0 (fi) 1982-06-16
HU188177B (en) 1986-03-28
ES8403868A1 (es) 1984-04-01
SE453595B (sv) 1988-02-15
KR890000769B1 (ko) 1989-04-05
FR2508040A1 (fr) 1982-12-24
ES520582A0 (es) 1984-04-01
IT8267772A0 (it) 1982-06-16
NL193282C (nl) 1999-05-06
NL8202472A (nl) 1983-01-17
IT1157053B (it) 1987-02-11
IL65954A0 (en) 1982-09-30
ATA558581A (de) 1984-08-15
PT75076A (en) 1982-07-01
FI822171L (fi) 1982-12-20
DK156054C (da) 1989-11-06
FI75804B (fi) 1988-04-29
DK156054B (da) 1989-06-19
NO156408C (no) 1987-09-16
NO821997L (no) 1982-12-20
GB2102412A (en) 1983-02-02
DE3222779C2 (es) 1991-01-03
MX155724A (es) 1988-04-20
CA1235120A (en) 1988-04-12
SU1316556A3 (ru) 1987-06-07
SE8203814L (sv) 1982-12-20
AT377496B (de) 1985-03-25
FR2508040B1 (fr) 1986-07-04

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20000526