GB2024010A - Compositions containing fatty acids for the treatment of seborrhoeic conditions - Google Patents

Compositions containing fatty acids for the treatment of seborrhoeic conditions Download PDF

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Publication number
GB2024010A
GB2024010A GB7921890A GB7921890A GB2024010A GB 2024010 A GB2024010 A GB 2024010A GB 7921890 A GB7921890 A GB 7921890A GB 7921890 A GB7921890 A GB 7921890A GB 2024010 A GB2024010 A GB 2024010A
Authority
GB
United Kingdom
Prior art keywords
acid
treatment
seborrhoeic
conditions
alcoholic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7921890A
Other versions
GB2024010B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WOLFF CHEM PHARM GmbH
Dr August Wolff GmbH and Co KG Arzneimittel
Original Assignee
WOLFF CHEM PHARM GmbH
Dr August Wolff GmbH and Co KG Arzneimittel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WOLFF CHEM PHARM GmbH, Dr August Wolff GmbH and Co KG Arzneimittel filed Critical WOLFF CHEM PHARM GmbH
Publication of GB2024010A publication Critical patent/GB2024010A/en
Application granted granted Critical
Publication of GB2024010B publication Critical patent/GB2024010B/en
Expired legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/008—Preparations for oily skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Detergent Compositions (AREA)

Abstract

A pharmaceutical composition is disclosed for the treatment of seborrhoeic conditions in man comprising a solution of a C8-C12 fatty acid, or mixture of such fatty acids in an alcoholic or aqueous alcoholic medium.

Description

SPECIFICATION Agents for the treatment of seborrhoeic conditions The invention relates to agents for the treatment of seborrhoeic conditions.
The treatment of seborrhoeic conditions in dermatology is still unsatisfactory in many respects. For the most widely varying reasons, all previously used agents and substances suffer from therapeutic disadvantages or disadvantages arising out of toxicological considerations. In comparison, the agents described hereinafter substantially avoid these disadvantages.
The invention lies in the use of mediumchain fatty acids containing 8-1 2 carbon atoms preferably decanoic acid (C10) and/or dodecanoic acid (C,2), in particular in alcoholic or aqueous-alcoholic solutions. The concentrations of the fatty acids and the mixture thereof in the solvents may be widely varied but will usually be in the range 1-40%. Likewise, the alcohol solvents may be widely varied as such, but may also be widely varied in their proportion of mixing with water or with each other.
The following examples illustrate the invention: Example 1 Decanoic acid (capric acid ) is dissolved in a 5% concentration in 96% ethyl alcohol, and used for the treatment of seborrhoeic conditions.
Example 2 Dodecanoic acid (lauric acid) is dissolved in a 5% concentration in isopropyl alcohol, and used for the treatment of seborrhoeic conditions.
Example 3 Decanoic acid (capric acid) is dissolved in a 5% concentration in propylene glycol and used for the treatment of seborrhoeic conditions.
Example 4 Decanoic acid (capric acid) is dissolved in a 10% concentration in a solution of polyethylene glycol 400, and used for the treatment of seborrhoeic conditions.
1. A composition for use in the treatment of seborrhoeic conditions comprising a C8-C12 fatty acid or mixture of such acids in alcoholic or aqueous alcoholic solution.
2. A composition according to claim 1, wherein the fatty acid is decanoic acid and/or dodecanoic acid.
3. A composition according to claim 1 or 2, wherein the concentration of fatty acid in said solution is from 1-40%.
4. A composition according to claim 1, 2 or 3, wherein the alcoholic solvent is ethyl alcohol, isopropyl alcohol, propylene glycol or polyethylene glycol.
5. A composition according to any one of claims 1-4, wherein the solvent medium is an aqueous alcoholic medium.
6. A C8-C,2 fatty acid or mixtures thereof for use in the treatment of seborrhoeic conditions in man.
7. A fatty acid according to claim 6, which is decanoic acid or dodecanoic acid, or a mixture of the two.
**WARNING** end of DESC field may overlap start of CLMS **.

Claims (7)

**WARNING** start of CLMS field may overlap end of DESC **. SPECIFICATION Agents for the treatment of seborrhoeic conditions The invention relates to agents for the treatment of seborrhoeic conditions. The treatment of seborrhoeic conditions in dermatology is still unsatisfactory in many respects. For the most widely varying reasons, all previously used agents and substances suffer from therapeutic disadvantages or disadvantages arising out of toxicological considerations. In comparison, the agents described hereinafter substantially avoid these disadvantages. The invention lies in the use of mediumchain fatty acids containing 8-1 2 carbon atoms preferably decanoic acid (C10) and/or dodecanoic acid (C,2), in particular in alcoholic or aqueous-alcoholic solutions. The concentrations of the fatty acids and the mixture thereof in the solvents may be widely varied but will usually be in the range 1-40%. Likewise, the alcohol solvents may be widely varied as such, but may also be widely varied in their proportion of mixing with water or with each other. The following examples illustrate the invention: Example 1 Decanoic acid (capric acid ) is dissolved in a 5% concentration in 96% ethyl alcohol, and used for the treatment of seborrhoeic conditions. Example 2 Dodecanoic acid (lauric acid) is dissolved in a 5% concentration in isopropyl alcohol, and used for the treatment of seborrhoeic conditions. Example 3 Decanoic acid (capric acid) is dissolved in a 5% concentration in propylene glycol and used for the treatment of seborrhoeic conditions. Example 4 Decanoic acid (capric acid) is dissolved in a 10% concentration in a solution of polyethylene glycol 400, and used for the treatment of seborrhoeic conditions. CLAIMS
1. A composition for use in the treatment of seborrhoeic conditions comprising a C8-C12 fatty acid or mixture of such acids in alcoholic or aqueous alcoholic solution.
2. A composition according to claim 1, wherein the fatty acid is decanoic acid and/or dodecanoic acid.
3. A composition according to claim 1 or 2, wherein the concentration of fatty acid in said solution is from 1-40%.
4. A composition according to claim 1, 2 or 3, wherein the alcoholic solvent is ethyl alcohol, isopropyl alcohol, propylene glycol or polyethylene glycol.
5. A composition according to any one of claims 1-4, wherein the solvent medium is an aqueous alcoholic medium.
6. A C8-C,2 fatty acid or mixtures thereof for use in the treatment of seborrhoeic conditions in man.
7. A fatty acid according to claim 6, which is decanoic acid or dodecanoic acid, or a mixture of the two.
GB7921890A 1978-06-28 1979-06-22 Compositions for containing fatty acids for the treatment of seborrhoeic conditions Expired GB2024010B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2828352A DE2828352C3 (en) 1978-06-28 1978-06-28 Agents for treating seborrheic conditions

Publications (2)

Publication Number Publication Date
GB2024010A true GB2024010A (en) 1980-01-09
GB2024010B GB2024010B (en) 1982-11-10

Family

ID=6043011

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7921890A Expired GB2024010B (en) 1978-06-28 1979-06-22 Compositions for containing fatty acids for the treatment of seborrhoeic conditions

Country Status (14)

Country Link
JP (1) JPS559069A (en)
AT (1) AT365450B (en)
BE (1) BE877351A (en)
CA (1) CA1142854A (en)
CH (1) CH641042A5 (en)
CS (1) CS439379A3 (en)
DE (1) DE2828352C3 (en)
DK (1) DK153738C (en)
FR (1) FR2437210A1 (en)
GB (1) GB2024010B (en)
IT (1) IT1124116B (en)
LU (1) LU81429A1 (en)
NL (1) NL7904776A (en)
SE (1) SE7905659L (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068552A2 (en) * 1981-06-23 1983-01-05 THE PROCTER & GAMBLE COMPANY Topical antimicrobial composition
EP0116439A2 (en) * 1983-02-02 1984-08-22 Suntory Limited Fatty acid containing hair tonic composition
DE3410850A1 (en) * 1983-03-25 1984-10-04 Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo MEDICINAL PRODUCTS FOR REINFORCING AND USING BLOOD VESSELS
US4839165A (en) * 1986-02-06 1989-06-13 Beiersdorf Aktiengesellschaft Cosmetic agents for hair
WO1994005253A2 (en) * 1992-09-05 1994-03-17 Beiersdorf Aktiengesellschaft Deodorizing cosmetics containing fatty acids
EP0702950A1 (en) * 1994-09-26 1996-03-27 Beiersdorf Aktiengesellschaft Use of fatty acids against skin superinfections
WO1998006378A1 (en) * 1996-08-13 1998-02-19 Pierre Fabre Dermo-Cosmetique Anti-seborrheic guanidine salts
WO2007068358A1 (en) * 2005-12-16 2007-06-21 Unilever Plc Skin benefit composition and a method for using the same

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2912438A1 (en) * 1979-03-29 1980-10-16 Eckert Theodor Topical treatment of skin diseases - with alcoholic soln. of fatty acid
JP5850453B2 (en) * 2012-01-04 2016-02-03 洋一 赤間 External skin analgesics, skin puncture pain relievers and subcutaneous vein vasodilators

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR46241E (en) * 1935-04-03 1936-04-02 Ig Farbenindustrie Ag Cosmetic product
GB801726A (en) * 1956-01-25 1958-09-17 Havva Rabinovitch Improvements in or relating to pharmaceutical preparations
GB1137125A (en) * 1965-12-08 1968-12-18 Unilever Ltd Improved soap products

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0068552A2 (en) * 1981-06-23 1983-01-05 THE PROCTER & GAMBLE COMPANY Topical antimicrobial composition
EP0068552A3 (en) * 1981-06-23 1984-03-28 THE PROCTER & GAMBLE COMPANY Topical antimicrobial composition
EP0116439A2 (en) * 1983-02-02 1984-08-22 Suntory Limited Fatty acid containing hair tonic composition
EP0116439A3 (en) * 1983-02-02 1986-01-29 Suntory Limited Fatty acid containing hair tonic composition
DE3410850A1 (en) * 1983-03-25 1984-10-04 Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo MEDICINAL PRODUCTS FOR REINFORCING AND USING BLOOD VESSELS
GB2140688A (en) * 1983-03-25 1984-12-05 Otsuka Pharma Co Ltd Fatty acid containing compositions
US4839165A (en) * 1986-02-06 1989-06-13 Beiersdorf Aktiengesellschaft Cosmetic agents for hair
WO1994005253A2 (en) * 1992-09-05 1994-03-17 Beiersdorf Aktiengesellschaft Deodorizing cosmetics containing fatty acids
WO1994005253A3 (en) * 1992-09-05 1994-04-14 Beiersdorf Ag Deodorizing cosmetics containing fatty acids
EP0702950A1 (en) * 1994-09-26 1996-03-27 Beiersdorf Aktiengesellschaft Use of fatty acids against skin superinfections
WO1998006378A1 (en) * 1996-08-13 1998-02-19 Pierre Fabre Dermo-Cosmetique Anti-seborrheic guanidine salts
FR2752421A1 (en) * 1996-08-13 1998-02-20 Fabre Pierre Dermo Cosmetique ANTI-SEBORRHEIC GUANIDINE SALTS
WO2007068358A1 (en) * 2005-12-16 2007-06-21 Unilever Plc Skin benefit composition and a method for using the same

Also Published As

Publication number Publication date
ATA419279A (en) 1981-06-15
BE877351A (en) 1979-10-15
DK153738B (en) 1988-08-29
FR2437210B1 (en) 1983-02-18
CS275816B6 (en) 1992-03-18
GB2024010B (en) 1982-11-10
IT1124116B (en) 1986-05-07
DK153738C (en) 1989-01-09
DE2828352C3 (en) 1981-08-20
AT365450B (en) 1982-01-11
IT7912655A0 (en) 1979-06-27
JPS559069A (en) 1980-01-22
CH641042A5 (en) 1984-02-15
DK271279A (en) 1979-12-29
LU81429A1 (en) 1979-10-30
FR2437210A1 (en) 1980-04-25
DE2828352B2 (en) 1980-09-25
SE7905659L (en) 1979-12-29
CS439379A3 (en) 1992-03-18
CA1142854A (en) 1983-03-15
NL7904776A (en) 1980-01-03
DE2828352A1 (en) 1980-01-17

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19930622