GB201611469D0 - Improvements in or relating to nucleic acid amplification processes - Google Patents

Improvements in or relating to nucleic acid amplification processes

Info

Publication number
GB201611469D0
GB201611469D0 GBGB1611469.6A GB201611469A GB201611469D0 GB 201611469 D0 GB201611469 D0 GB 201611469D0 GB 201611469 A GB201611469 A GB 201611469A GB 201611469 D0 GB201611469 D0 GB 201611469D0
Authority
GB
United Kingdom
Prior art keywords
relating
nucleic acid
acid amplification
amplification processes
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1611469.6A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LKM Innovations Ltd
Original Assignee
LumiraDx Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56891177&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB201611469(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by LumiraDx Technology Ltd filed Critical LumiraDx Technology Ltd
Priority to GBGB1611469.6A priority Critical patent/GB201611469D0/en
Publication of GB201611469D0 publication Critical patent/GB201611469D0/en
Priority to SG11201809927XA priority patent/SG11201809927XA/en
Priority to EP17736737.2A priority patent/EP3478853B2/en
Priority to MX2018015421A priority patent/MX2018015421A/es
Priority to CA3024295A priority patent/CA3024295C/en
Priority to RU2019101504A priority patent/RU2760915C2/ru
Priority to KR1020187035782A priority patent/KR102392010B1/ko
Priority to PCT/GB2017/051927 priority patent/WO2018002649A1/en
Priority to CN201780040770.0A priority patent/CN109642251B/zh
Priority to JP2018565020A priority patent/JP6957527B2/ja
Priority to AU2017287852A priority patent/AU2017287852B2/en
Priority to BR112018075801-9A priority patent/BR112018075801B1/pt
Priority to ES17736737T priority patent/ES2841624T3/es
Priority to US16/313,750 priority patent/US11591643B2/en
Priority to ZA2018/07460A priority patent/ZA201807460B/en
Priority to IL263870A priority patent/IL263870A/en
Priority to JP2021164854A priority patent/JP2022017268A/ja
Priority to US18/102,031 priority patent/US20230340579A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/10—Nucleotidyl transfering
    • C12Q2521/101—DNA polymerase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/10—Nucleotidyl transfering
    • C12Q2521/107—RNA dependent DNA polymerase,(i.e. reverse transcriptase)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/30—Phosphoric diester hydrolysing, i.e. nuclease
    • C12Q2521/307—Single strand endonuclease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2521/00—Reaction characterised by the enzymatic activity
    • C12Q2521/50—Other enzymatic activities
    • C12Q2521/531—Glycosylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/113—Modifications characterised by incorporating modified backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/10—Modifications characterised by
    • C12Q2525/131—Modifications characterised by incorporating a restriction site
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
    • C12Q2525/30—Oligonucleotides characterised by their secondary structure
    • C12Q2525/301—Hairpin oligonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/101—Temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/137—Reactions characterised by the reaction format or use of a specific feature the purpose or use of a displacement step

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Clinical Laboratory Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
GBGB1611469.6A 2016-06-30 2016-06-30 Improvements in or relating to nucleic acid amplification processes Ceased GB201611469D0 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
GBGB1611469.6A GB201611469D0 (en) 2016-06-30 2016-06-30 Improvements in or relating to nucleic acid amplification processes
ES17736737T ES2841624T3 (es) 2016-06-30 2017-06-30 Mejoras en o relacionadas con procedimientos de amplificación de ácidos nucleicos
US16/313,750 US11591643B2 (en) 2016-06-30 2017-06-30 In or relating to uncleic acid amplification processes
PCT/GB2017/051927 WO2018002649A1 (en) 2016-06-30 2017-06-30 Improvements in or relating to nucleic acid amplification processes
AU2017287852A AU2017287852B2 (en) 2016-06-30 2017-06-30 Improvements in or relating to Nucleic Acid amplification processes
MX2018015421A MX2018015421A (es) 2016-06-30 2017-06-30 Mejoras en o relacionadas con los procesos de amplificacion de acidos nucleicos.
CA3024295A CA3024295C (en) 2016-06-30 2017-06-30 IMPROVEMENTS TO OR RELATING TO NUCLEIC ACID AMPLIFICATION PROCESSES
RU2019101504A RU2760915C2 (ru) 2016-06-30 2017-06-30 Усовершенствования в процессах амплификации нуклеиновой кислоты или связанные с таковыми
KR1020187035782A KR102392010B1 (ko) 2016-06-30 2017-06-30 핵산 증폭 방법의 개선 또는 핵산 증폭 방법과 관련한 개선
SG11201809927XA SG11201809927XA (en) 2016-06-30 2017-06-30 Improvements in or relating to nucleic acid amplification processes
CN201780040770.0A CN109642251B (zh) 2016-06-30 2017-06-30 核酸扩增过程中的改进或与核酸扩增过程相关的改进
JP2018565020A JP6957527B2 (ja) 2016-06-30 2017-06-30 核酸増幅プロセスの改善または核酸増幅プロセスに関する改善
EP17736737.2A EP3478853B2 (en) 2016-06-30 2017-06-30 Improvements in or relating to nucleic acid amplification processes
BR112018075801-9A BR112018075801B1 (pt) 2016-06-30 2017-06-30 Método para realizar uma reação de amplificação de ácido nucleico não isotérmico e aparelho para realizar o método
ZA2018/07460A ZA201807460B (en) 2016-06-30 2018-11-07 Improvements in or relating to nucleic acid amplification processes
IL263870A IL263870A (en) 2016-06-30 2018-12-20 Improvements in or relating to nucleic acid amplification processes
JP2021164854A JP2022017268A (ja) 2016-06-30 2021-10-06 核酸増幅プロセスの改善または核酸増幅プロセスに関する改善
US18/102,031 US20230340579A1 (en) 2016-06-30 2023-01-26 Nucleic acid amplification processes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1611469.6A GB201611469D0 (en) 2016-06-30 2016-06-30 Improvements in or relating to nucleic acid amplification processes

Publications (1)

Publication Number Publication Date
GB201611469D0 true GB201611469D0 (en) 2016-08-17

Family

ID=56891177

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1611469.6A Ceased GB201611469D0 (en) 2016-06-30 2016-06-30 Improvements in or relating to nucleic acid amplification processes

Country Status (15)

Country Link
US (2) US11591643B2 (cg-RX-API-DMAC7.html)
EP (1) EP3478853B2 (cg-RX-API-DMAC7.html)
JP (2) JP6957527B2 (cg-RX-API-DMAC7.html)
KR (1) KR102392010B1 (cg-RX-API-DMAC7.html)
CN (1) CN109642251B (cg-RX-API-DMAC7.html)
AU (1) AU2017287852B2 (cg-RX-API-DMAC7.html)
CA (1) CA3024295C (cg-RX-API-DMAC7.html)
ES (1) ES2841624T3 (cg-RX-API-DMAC7.html)
GB (1) GB201611469D0 (cg-RX-API-DMAC7.html)
IL (1) IL263870A (cg-RX-API-DMAC7.html)
MX (1) MX2018015421A (cg-RX-API-DMAC7.html)
RU (1) RU2760915C2 (cg-RX-API-DMAC7.html)
SG (1) SG11201809927XA (cg-RX-API-DMAC7.html)
WO (1) WO2018002649A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201807460B (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201611469D0 (en) 2016-06-30 2016-08-17 Lumiradx Tech Ltd Improvements in or relating to nucleic acid amplification processes
GB2569965A (en) * 2018-01-04 2019-07-10 Lumiradx Uk Ltd Improvements in or relating to amplification of nucleic acids
GB201812149D0 (en) 2018-07-25 2018-09-05 Sense Biodetection Ltd Nucleic acid detection method
GB201915346D0 (en) 2019-06-21 2019-12-04 Lumiradx Tech Ltd Improvements in or relating to nicking enzymes
BR112022014535A2 (pt) 2020-01-25 2022-09-20 Sense Biodetection Ltd Detecção de vírus
PT3969618T (pt) * 2020-03-09 2023-11-15 Illumina Inc Métodos para sequenciação de polinucleótidos
EP4347868A1 (en) 2021-05-27 2024-04-10 Lumiradx Uk Ltd Improvements in or relating to digestion of reaction products
US12331157B2 (en) 2021-09-16 2025-06-17 Circ, LLC Method of forming a polyester from a regenerated diacid formed from depolymerization of a waste material
US20230082247A1 (en) * 2021-09-16 2023-03-16 Circ, LLC Method of aging regenerated diacid crystals

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017821C1 (ru) * 1990-10-10 1994-08-15 Анатолий Михайлович Онищенко Способ амплификации днк и устройство для его осуществления
US5432065A (en) 1993-03-30 1995-07-11 United States Biochemical Corporation Cycle sequencing with non-thermostable DNA polymerases
US20020025555A1 (en) * 1997-03-06 2002-02-28 Janice Au-Young GPCR diagnostic for brain cancer
WO1999037805A1 (en) 1998-01-27 1999-07-29 Cytocell Limited Method for detection of nucleic acid target sequences involving in vitro transcription from an rna promoter
ATE286981T1 (de) 1999-09-28 2005-01-15 Roche Diagnostics Gmbh Thermostabiles enzym welches die genauigkeit thermostabiler dna polymerasen erhöht - zur verbesserung der nucleinsäuresynthese und in vitro amplifikation
US20010047200A1 (en) 1999-10-13 2001-11-29 Raymond Sun Non-foreshortening intraluminal prosthesis
NO314091B1 (no) * 2000-01-12 2003-01-27 Biotec Pharmacon Asa Varmelabil uracil-DNA-glykosylase, DNA-sekvens som koder for enzymet, mikroorganisme som inneholder DNA-sekvensen, samt anvendelse av enzymet
US6191267B1 (en) 2000-06-02 2001-02-20 New England Biolabs, Inc. Cloning and producing the N.BstNBI nicking endonuclease
DE60115811T2 (de) 2000-10-25 2006-08-03 Roche Diagnostics Gmbh Amplifizierung unter Verwendung von modifizierten Primern
GB0101397D0 (en) 2001-01-19 2001-03-07 Amersham Pharm Biotech Uk Ltd Suppression of non-specific nucleic acid amplication
US20030211506A1 (en) 2001-06-01 2003-11-13 Huimin Kong N. bstnbi nicking endonuclease and methods for using endonucleases in single-stranded displacement amplification
WO2003008622A2 (en) * 2001-07-15 2003-01-30 Keck Graduate Institute Exponential nucleic acid amplification using nicking endonucleases
AU2002217428A1 (en) 2001-12-04 2003-06-17 Bio3 Research Srl Mixture of two partially denaturating agents for the preparation of pcr buffer solutions
US7399590B2 (en) 2002-02-21 2008-07-15 Asm Scientific, Inc. Recombinase polymerase amplification
WO2004055193A1 (en) 2002-12-18 2004-07-01 Dingbang Xu Pcr method and application by transnormal low thermo-denaturation temperature
JP4567673B2 (ja) 2003-04-01 2010-10-20 エラジェン バイオサイエンシズ インコーポレイテッド ポリメラーゼ阻害剤およびその使用方法
EP3985125A1 (en) 2004-06-01 2022-04-20 Abbott Diagnostics Scarborough, Inc. Recombinase polymerase amplification
EP1771250B1 (en) 2004-06-04 2011-01-26 Abacus Diagnostica OY Temperature control of reaction vessel, system with reaction vessel and use of system
FR2878254B1 (fr) * 2004-11-22 2010-08-20 Bio Rad Pasteur Composition pour l'amplification d'acides nucleiques
EP1762627A1 (de) 2005-09-09 2007-03-14 Qiagen GmbH Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
US7537917B2 (en) 2006-03-31 2009-05-26 Collins Michael J Microwave assisted PCR amplification of DNA
US20090092967A1 (en) 2006-06-26 2009-04-09 Epoch Biosciences, Inc. Method for generating target nucleic acid sequences
DK2574681T3 (en) 2007-03-28 2016-07-04 Signal Diagnostics System and method for high-resolution analysis of nucleic acids to detect sequence variations
US9689031B2 (en) * 2007-07-14 2017-06-27 Ionian Technologies, Inc. Nicking and extension amplification reaction for the exponential amplification of nucleic acids
WO2009042291A2 (en) * 2007-08-03 2009-04-02 Igor Kutyavin Accelerated cascade amplification (aca) of nucleic acids comprising strand and sequence specific dna nicking
FI20085450A0 (fi) 2008-05-14 2008-05-14 Arto Orpana Menetelmä DNA-juosteen syntetisoimiseksi
GB0915664D0 (en) 2009-09-08 2009-10-07 Enigma Diagnostics Ltd Reaction method
AU2010298202B2 (en) 2009-09-25 2015-11-05 Alere San Diego, Inc. Detection of nucleic acids in crude matrices
US9501070B2 (en) * 2010-04-20 2016-11-22 Qiagen Instruments Ag Temperature control method and apparatus
WO2012077819A1 (ja) 2010-12-10 2012-06-14 国立大学法人 東京工業大学 標的核酸の検出方法及びキット
EP2652148B1 (en) 2010-12-17 2016-11-30 Life Technologies Corporation Methods, compositions, systems, apparatuses and kits for nucleic acid amplification
EP2699700B8 (en) 2011-04-20 2016-08-24 Mesa Biotech, Inc. Integrated device for nucleic acid detection and identification
US8343752B2 (en) * 2011-05-03 2013-01-01 Verdezyne, Inc. Biological methods for preparing adipic acid
US9096897B2 (en) * 2012-04-09 2015-08-04 Envirologix Inc. Compositions and methods for quantifying a nucleic acid sequence in a sample comprising a primer oligonucleotide with a 3′-terminal region comprising a 2′-modified nucleotide
CA2876159C (en) 2012-06-08 2022-09-06 Ionian Technologies, Inc. Nucleic acid amplifications
EP3094753B1 (en) 2014-01-15 2019-10-16 Abbott Laboratories Covered sequence conversion dna and detection methods
ES2759339T3 (es) 2014-10-14 2020-05-08 Abbott Lab Conversión de secuencia y ADN amplificador de señal que tiene ácidos nucleicos bloqueados y métodos de detección que usan los mismos
WO2016103234A1 (en) 2014-12-24 2016-06-30 Abbott Japan Co., Ltd. Detection method based on signal amplifier dna cascade reactions with target extension
GB201513128D0 (en) 2015-07-24 2015-09-09 Sense Biodetection Ltd Nucleic acid detection method
EP3334834B1 (en) 2015-08-12 2020-05-13 Circulogene Theranostics, LLC Method of preparing cell free nucleic acid molecules by in situ amplification
US10329601B2 (en) 2015-12-28 2019-06-25 Ionian Technologies, Inc. Nicking and extension amplification reaction (NEAR) of Streptococcus species
GB201611469D0 (en) 2016-06-30 2016-08-17 Lumiradx Tech Ltd Improvements in or relating to nucleic acid amplification processes
GB201701262D0 (en) 2017-01-25 2017-03-08 Sense Biodetection Ltd Nucleic acid detection method
RU2020100221A (ru) 2017-08-31 2021-09-30 Иониан Текнолоджис, Ллс Реакция амплификации с разрывом и удлинением (near) разновидностей респираторно-синцитиального вируса
GB2569965A (en) 2018-01-04 2019-07-10 Lumiradx Uk Ltd Improvements in or relating to amplification of nucleic acids
GB201812149D0 (en) 2018-07-25 2018-09-05 Sense Biodetection Ltd Nucleic acid detection method

Also Published As

Publication number Publication date
AU2017287852A1 (en) 2018-11-22
US20190226015A1 (en) 2019-07-25
ZA201807460B (en) 2021-06-30
MX2018015421A (es) 2019-11-28
CA3024295C (en) 2024-09-24
JP6957527B2 (ja) 2021-11-02
RU2760915C2 (ru) 2021-12-01
SG11201809927XA (en) 2019-01-30
KR20190024890A (ko) 2019-03-08
US11591643B2 (en) 2023-02-28
EP3478853B2 (en) 2025-11-26
AU2017287852B2 (en) 2022-11-24
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RU2019101504A3 (cg-RX-API-DMAC7.html) 2020-11-30
CN109642251A (zh) 2019-04-16
CA3024295A1 (en) 2018-01-04
ES2841624T3 (es) 2021-07-08
EP3478853A1 (en) 2019-05-08
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BR112018075801A2 (pt) 2019-03-26
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JP2019519231A (ja) 2019-07-11
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