GB2014987B - Mercaptoacylamino acids - Google Patents

Mercaptoacylamino acids

Info

Publication number
GB2014987B
GB2014987B GB7905788A GB7905788A GB2014987B GB 2014987 B GB2014987 B GB 2014987B GB 7905788 A GB7905788 A GB 7905788A GB 7905788 A GB7905788 A GB 7905788A GB 2014987 B GB2014987 B GB 2014987B
Authority
GB
United Kingdom
Prior art keywords
mercaptoacylamino acids
mercaptoacylamino
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7905788A
Other languages
English (en)
Other versions
GB2014987A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/939,147 external-priority patent/US4154935A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of GB2014987A publication Critical patent/GB2014987A/en
Application granted granted Critical
Publication of GB2014987B publication Critical patent/GB2014987B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
GB7905788A 1978-02-21 1979-02-19 Mercaptoacylamino acids Expired GB2014987B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87903278A 1978-02-21 1978-02-21
US93914878A 1978-09-01 1978-09-01
US05/939,147 US4154935A (en) 1978-02-21 1978-09-01 Halogen substituted mercaptoacylamino acids

Publications (2)

Publication Number Publication Date
GB2014987A GB2014987A (en) 1979-09-05
GB2014987B true GB2014987B (en) 1982-11-03

Family

ID=27420501

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7905788A Expired GB2014987B (en) 1978-02-21 1979-02-19 Mercaptoacylamino acids

Country Status (26)

Country Link
JP (1) JPS54125656A (pl)
AR (2) AR229152A1 (pl)
CA (1) CA1124723A (pl)
CH (1) CH639370A5 (pl)
CS (1) CS230562B2 (pl)
DD (1) DD141827A5 (pl)
DE (1) DE2906768A1 (pl)
DK (1) DK73379A (pl)
ES (3) ES477878A1 (pl)
FI (1) FI790593A (pl)
FR (1) FR2417499A1 (pl)
GB (1) GB2014987B (pl)
GR (1) GR82336B (pl)
HK (1) HK41383A (pl)
IE (1) IE47971B1 (pl)
IL (1) IL56662A0 (pl)
LU (1) LU80946A1 (pl)
NL (1) NL7901319A (pl)
NO (1) NO790568L (pl)
NZ (1) NZ189626A (pl)
PH (1) PH15381A (pl)
PL (1) PL118158B1 (pl)
PT (1) PT69254A (pl)
RO (1) RO77228A (pl)
SE (1) SE431643B (pl)
SU (1) SU882409A3 (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1144930A (en) * 1978-08-11 1983-04-19 Miguel A. Ondetti Mercaptoacyl derivatives of substituted prolines
NL7809120A (nl) * 1978-09-07 1980-03-11 Oce Andeno B V Grubbenvorsterw Werkwijze voor de bereiding van proline-derivaten.
US4483861A (en) * 1978-10-31 1984-11-20 Santen Pharmaceutical Co., Ltd. Antihypertensive sulfur-containing compounds
CA1132985A (en) * 1978-12-22 1982-10-05 John Krapcho Ketal and thioketal derivatives of mercaptoacyl prolines
ZA802420B (en) * 1979-05-18 1981-04-29 Squibb & Sons Inc Aminoacyl derivatives of mercaptoacyl amino acids
US4288368A (en) * 1979-07-30 1981-09-08 E. R. Squibb & Sons, Inc. Dithioacylproline derivatives
AU542211B2 (en) * 1980-03-07 1985-02-14 Gruppo Lepetit S.P.A. Mercaptocycloalkyl carbonyl prolines
JP2005213165A (ja) * 2004-01-28 2005-08-11 Mitsui Chemicals Inc フルオロプロリン類の製造方法
JP2011121872A (ja) * 2009-12-08 2011-06-23 Central Glass Co Ltd 光学活性N−tert−ブトキシカルボニル−トランス−4−フルオロプロリンの精製方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds

Also Published As

Publication number Publication date
HK41383A (en) 1983-10-21
FR2417499B1 (pl) 1982-06-04
ES477878A1 (es) 1980-03-01
NO790568L (no) 1979-08-22
IE47971B1 (en) 1984-08-08
GB2014987A (en) 1979-09-05
AR229152A1 (es) 1983-06-30
JPH0134986B2 (pl) 1989-07-21
LU80946A1 (fr) 1979-06-18
RO77228A (ro) 1981-08-17
CS230562B2 (en) 1984-08-13
IE790297L (en) 1979-08-21
ES479832A1 (es) 1979-11-16
ES479833A1 (es) 1979-11-16
JPS54125656A (en) 1979-09-29
CH639370A5 (fr) 1983-11-15
SE431643B (sv) 1984-02-20
SU882409A3 (ru) 1981-11-15
PT69254A (en) 1979-03-01
PH15381A (en) 1982-12-17
SE7901510L (sv) 1979-08-22
PL118158B1 (en) 1981-09-30
NL7901319A (nl) 1979-08-23
PL213593A1 (pl) 1980-02-25
NZ189626A (en) 1982-03-09
DK73379A (da) 1979-08-22
FR2417499A1 (fr) 1979-09-14
DE2906768A1 (de) 1979-08-23
FI790593A (fi) 1979-08-22
IL56662A0 (en) 1979-05-31
AR228036A1 (es) 1983-01-14
GR82336B (pl) 1984-12-13
CA1124723A (en) 1982-06-01
DD141827A5 (de) 1980-05-21

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19940219