GB201405921D0 - Novel methods for inducing an immune response - Google Patents

Novel methods for inducing an immune response

Info

Publication number
GB201405921D0
GB201405921D0 GBGB1405921.6A GB201405921A GB201405921D0 GB 201405921 D0 GB201405921 D0 GB 201405921D0 GB 201405921 A GB201405921 A GB 201405921A GB 201405921 D0 GB201405921 D0 GB 201405921D0
Authority
GB
United Kingdom
Prior art keywords
inducing
immune response
novel methods
novel
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1405921.6A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
GlaxoSmithKline Biologicals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline Biologicals SA filed Critical GlaxoSmithKline Biologicals SA
Priority to GBGB1405921.6A priority Critical patent/GB201405921D0/en
Publication of GB201405921D0 publication Critical patent/GB201405921D0/en
Priority to MX2016012932A priority patent/MX2016012932A/es
Priority to CA2943711A priority patent/CA2943711A1/en
Priority to CA2943007A priority patent/CA2943007C/en
Priority to AU2015239025A priority patent/AU2015239025B2/en
Priority to KR1020167029523A priority patent/KR20160132115A/ko
Priority to BE2015/5209A priority patent/BE1022355B1/fr
Priority to PCT/EP2015/057424 priority patent/WO2015150568A1/en
Priority to PCT/EP2015/057423 priority patent/WO2015150567A1/en
Priority to KR1020237017095A priority patent/KR102762440B1/ko
Priority to IL247493A priority patent/IL247493B/en
Priority to BR112016022463A priority patent/BR112016022463A2/pt
Priority to EP15713531.0A priority patent/EP3125930B1/en
Priority to ES15713531T priority patent/ES2853773T3/es
Priority to CN201580030331.2A priority patent/CN106456739A/zh
Priority to MX2016012982A priority patent/MX2016012982A/es
Priority to SG11201607086QA priority patent/SG11201607086QA/en
Priority to EA201691638A priority patent/EA037405B1/ru
Priority to JP2016560336A priority patent/JP6655549B2/ja
Priority to ES15713532T priority patent/ES2961840T3/es
Priority to EP15713532.8A priority patent/EP3125929B8/en
Priority to US15/300,338 priority patent/US10624961B2/en
Priority to JP2016559965A priority patent/JP6645982B2/ja
Priority to CN201580016665.4A priority patent/CN106456738B/zh
Priority to BR112016022787-5A priority patent/BR112016022787A2/pt
Priority to US15/300,852 priority patent/US10688168B2/en
Priority to ARP150101025A priority patent/AR099960A1/es
Priority to ZA2016/05955A priority patent/ZA201605955B/en
Priority to MX2022013912A priority patent/MX2022013912A/es
Priority to US16/815,635 priority patent/US11951161B2/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GBGB1405921.6A 2014-04-02 2014-04-02 Novel methods for inducing an immune response Ceased GB201405921D0 (en)

Priority Applications (30)

Application Number Priority Date Filing Date Title
GBGB1405921.6A GB201405921D0 (en) 2014-04-02 2014-04-02 Novel methods for inducing an immune response
US15/300,852 US10688168B2 (en) 2014-04-02 2015-04-02 Methods for inducing an immune response
CN201580030331.2A CN106456739A (zh) 2014-04-02 2015-04-02 用于诱导免疫应答的新方法
MX2016012982A MX2016012982A (es) 2014-04-02 2015-04-02 Procedimientos novedosos para inducir una respuesta inmunitaria.
CA2943007A CA2943007C (en) 2014-04-02 2015-04-02 Novel methods for inducing an immune response
AU2015239025A AU2015239025B2 (en) 2014-04-02 2015-04-02 Novel methods for inducing an immune response
KR1020167029523A KR20160132115A (ko) 2014-04-02 2015-04-02 면역 반응을 유도하기 위한 신규한 방법
BE2015/5209A BE1022355B1 (fr) 2014-04-02 2015-04-02 Nouvelles méthodes d'induction d'une réponse immunitaire
PCT/EP2015/057424 WO2015150568A1 (en) 2014-04-02 2015-04-02 Novel methods for inducing an immune response
PCT/EP2015/057423 WO2015150567A1 (en) 2014-04-02 2015-04-02 Novel methods for inducing an immune response
KR1020237017095A KR102762440B1 (ko) 2014-04-02 2015-04-02 면역 반응을 유도하기 위한 신규한 방법
IL247493A IL247493B (en) 2014-04-02 2015-04-02 Novel methods for inducing an immune response
BR112016022463A BR112016022463A2 (pt) 2014-04-02 2015-04-02 método para induzir uma resposta imune em um indivíduo, primeira e segunda composições imunogênicas, e, uso de uma primeira composição imunogênica e de uma segunda composição imunogênica
EP15713531.0A EP3125930B1 (en) 2014-04-02 2015-04-02 Novel methods for inducing an immune response
ES15713531T ES2853773T3 (es) 2014-04-02 2015-04-02 Procedimientos novedosos para inducir una respuesta inmune
MX2016012932A MX2016012932A (es) 2014-04-02 2015-04-02 Procedimientos novedosos para inducir una respuesta inmune.
SG11201607086QA SG11201607086QA (en) 2014-04-02 2015-04-02 Novel methods for inducing an immune response
US15/300,338 US10624961B2 (en) 2014-04-02 2015-04-02 Methods for inducing an immune response
CN201580016665.4A CN106456738B (zh) 2014-04-02 2015-04-02 诱导免疫应答的新方法
JP2016560336A JP6655549B2 (ja) 2014-04-02 2015-04-02 免疫応答を誘導するための新規方法
ES15713532T ES2961840T3 (es) 2014-04-02 2015-04-02 Nuevos métodos para inducir una respuesta inmunitaria
EP15713532.8A EP3125929B8 (en) 2014-04-02 2015-04-02 Novel methods for inducing an immune response
CA2943711A CA2943711A1 (en) 2014-04-02 2015-04-02 Novel methods for inducing an immune response
JP2016559965A JP6645982B2 (ja) 2014-04-02 2015-04-02 免疫応答を誘導するための新規の方法
EA201691638A EA037405B1 (ru) 2014-04-02 2015-04-02 Способ индуцирования иммунного ответа против малярии
BR112016022787-5A BR112016022787A2 (pt) 2014-04-02 2015-04-02 método para induzir uma resposta imune em um indivíduo humano, composição imunogênica, e, uso de uma segunda composição imunogênica
ARP150101025A AR099960A1 (es) 2014-04-02 2015-04-06 Procedimientos y composición farmaceutica para inducir una respuesta inmunitaria
ZA2016/05955A ZA201605955B (en) 2014-04-02 2016-08-26 Novel methods for inducing an immune response
MX2022013912A MX2022013912A (es) 2014-04-02 2016-09-30 Procedimientos novedosos para inducir una respuesta inmunitaria.
US16/815,635 US11951161B2 (en) 2014-04-02 2020-03-11 Methods for inducing an immune response

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1405921.6A GB201405921D0 (en) 2014-04-02 2014-04-02 Novel methods for inducing an immune response

Publications (1)

Publication Number Publication Date
GB201405921D0 true GB201405921D0 (en) 2014-05-14

Family

ID=50737873

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1405921.6A Ceased GB201405921D0 (en) 2014-04-02 2014-04-02 Novel methods for inducing an immune response

Country Status (18)

Country Link
US (3) US10624961B2 (enExample)
EP (2) EP3125930B1 (enExample)
JP (2) JP6645982B2 (enExample)
KR (2) KR102762440B1 (enExample)
CN (2) CN106456738B (enExample)
AR (1) AR099960A1 (enExample)
AU (1) AU2015239025B2 (enExample)
BE (1) BE1022355B1 (enExample)
BR (2) BR112016022463A2 (enExample)
CA (2) CA2943007C (enExample)
EA (1) EA037405B1 (enExample)
ES (2) ES2961840T3 (enExample)
GB (1) GB201405921D0 (enExample)
IL (1) IL247493B (enExample)
MX (3) MX2016012932A (enExample)
SG (1) SG11201607086QA (enExample)
WO (2) WO2015150567A1 (enExample)
ZA (1) ZA201605955B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201405921D0 (en) * 2014-04-02 2014-05-14 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response
GB201621686D0 (en) * 2016-12-20 2017-02-01 Glaxosmithkline Biologicals Sa Novel methods for inducing an immune response
EP3630176A1 (en) 2017-05-30 2020-04-08 GlaxoSmithKline Biologicals S.A. Methods for manufacturing an adjuvant
EP3717001A1 (en) 2017-12-01 2020-10-07 GlaxoSmithKline Biologicals S.A. Saponin purification
US20220235095A1 (en) 2019-06-05 2022-07-28 Glaxosmithkline Biologicals Sa Saponin purification
CN113125756B (zh) * 2020-07-15 2022-10-25 南京岚煜生物科技有限公司 抗体标准品赋值和抗原中和当量确定的方法

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US152200A (en) * 1874-06-16 Improvement in garters
US1002607A (en) * 1905-08-28 1911-09-05 John Willard Taylor Paper pulley.
UA56132C2 (uk) * 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
EP1569515A4 (en) 2002-10-23 2006-04-26 Glaxosmithkline Biolog Sa MALARIA vaccine method
SI1802336T1 (sl) 2004-10-14 2012-01-31 Crucell Holland Bv Začetna/obnovitvena cepiva proti malariji
HRP20120331T1 (hr) * 2005-04-29 2012-05-31 Glaxosmithkline Biologicals Sa Postupak sprječavanja ili liječenja infekcije bakterijom m. tuberculosis
TWI457133B (zh) * 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
CA2668100C (en) * 2006-11-01 2014-12-23 Immport Therapeutics, Inc. Compositions and methods for immunodominant antigens
AU2008223951B2 (en) * 2007-03-02 2014-03-27 Glaxosmithkline Biologicals S.A. Novel method and compositions
AR066405A1 (es) * 2007-04-20 2009-08-19 Glaxosmithkline Biolog Sa Vacuna
LT2315773T (lt) * 2008-07-25 2016-11-10 Glaxosmithkline Biologicals S.A. Polipeptidai, polinukleotidai ir kompozicijos, skirti naudoti latentinės tuberkuliozės gydymui
EP2315597B1 (en) * 2008-07-25 2017-08-23 GlaxoSmithKline Biologicals S.A. Novel compositions and methods
PL2315834T3 (pl) * 2008-07-25 2018-12-31 Glaxosmithkline Biologicals S.A. Białko rv2386c związane z gruźlicą, jego kompozycje i zastosowania
CN102869372B (zh) * 2010-01-27 2016-01-20 葛兰素史密丝克莱恩生物有限公司 经修饰的结核抗原
AU2011343367B2 (en) * 2010-12-14 2015-05-21 Glaxosmithkline Biologicals S.A. Mycobacterium antigenic composition
US20170056345A1 (en) * 2014-02-18 2017-03-02 Stc.Unm Booster drug therapy for mycobacterium infections
GB201405921D0 (en) * 2014-04-02 2014-05-14 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response
US10004793B2 (en) * 2014-04-24 2018-06-26 Statens Serum Institut M.tuberculosis vaccines
GB201513176D0 (en) * 2015-07-27 2015-09-09 Glaxosmithkline Biolog Sa Novel methods for inducing an immune response

Also Published As

Publication number Publication date
EP3125929B1 (en) 2023-11-01
EA037405B1 (ru) 2021-03-25
WO2015150568A1 (en) 2015-10-08
ES2853773T3 (es) 2021-09-17
BE1022355B1 (fr) 2016-03-26
CN106456738A (zh) 2017-02-22
CA2943007A1 (en) 2015-10-08
ES2961840T3 (es) 2024-03-14
EP3125929A1 (en) 2017-02-08
AU2015239025B2 (en) 2018-01-25
US11951161B2 (en) 2024-04-09
KR102762440B1 (ko) 2025-02-03
CN106456738B (zh) 2021-06-29
IL247493B (en) 2022-08-01
EP3125930B1 (en) 2020-12-02
IL247493A0 (en) 2016-11-30
JP2017511324A (ja) 2017-04-20
US20200306353A1 (en) 2020-10-01
JP2017511327A (ja) 2017-04-20
US20170136110A1 (en) 2017-05-18
EP3125929B8 (en) 2023-12-27
JP6655549B2 (ja) 2020-02-26
SG11201607086QA (en) 2016-09-29
BR112016022787A2 (pt) 2018-03-27
EP3125929C0 (en) 2023-11-01
CA2943711A1 (en) 2015-10-08
US20170112914A1 (en) 2017-04-27
AU2015239025A1 (en) 2016-09-22
CN106456739A (zh) 2017-02-22
EP3125930A1 (en) 2017-02-08
ZA201605955B (en) 2019-04-24
EA201691638A1 (ru) 2017-04-28
AR099960A1 (es) 2016-08-31
US10688168B2 (en) 2020-06-23
BE1022355A1 (fr) 2016-02-16
US10624961B2 (en) 2020-04-21
WO2015150567A1 (en) 2015-10-08
KR20160132115A (ko) 2016-11-16
BR112016022463A2 (pt) 2017-10-10
MX2016012982A (es) 2016-12-07
MX2022013912A (es) 2022-12-13
CA2943007C (en) 2024-01-09
MX2016012932A (es) 2016-12-07
KR20230075525A (ko) 2023-05-31
JP6645982B2 (ja) 2020-02-14

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