GB201208961D0 - 2 dimensional MSMS - Google Patents

2 dimensional MSMS

Info

Publication number
GB201208961D0
GB201208961D0 GBGB1208961.1A GB201208961A GB201208961D0 GB 201208961 D0 GB201208961 D0 GB 201208961D0 GB 201208961 A GB201208961 A GB 201208961A GB 201208961 D0 GB201208961 D0 GB 201208961D0
Authority
GB
United Kingdom
Prior art keywords
mass
ions
fragment
precursor
ion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1208961.1A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Priority to GBGB1208961.1A priority Critical patent/GB201208961D0/en
Publication of GB201208961D0 publication Critical patent/GB201208961D0/en
Priority to CA2873610A priority patent/CA2873610C/en
Priority to JP2015512116A priority patent/JP6309508B2/ja
Priority to PCT/GB2013/051199 priority patent/WO2013171459A2/en
Priority to EP21186501.9A priority patent/EP3926659B1/en
Priority to GB1308297.9A priority patent/GB2504373B/en
Priority to EP13722022.4A priority patent/EP2850636B1/en
Priority to US14/401,228 priority patent/US9460902B2/en
Priority to US15/283,863 priority patent/US10068754B2/en
Ceased legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0031—Step by step routines describing the use of the apparatus
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H01J49/005—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by collision with gas, e.g. by introducing gas or by accelerating ions with an electric field
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
GBGB1208961.1A 2012-05-18 2012-05-18 2 dimensional MSMS Ceased GB201208961D0 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
GBGB1208961.1A GB201208961D0 (en) 2012-05-18 2012-05-18 2 dimensional MSMS
CA2873610A CA2873610C (en) 2012-05-18 2013-05-09 Method of identifying precursor ions
JP2015512116A JP6309508B2 (ja) 2012-05-18 2013-05-09 前駆イオンの同定方法
PCT/GB2013/051199 WO2013171459A2 (en) 2012-05-18 2013-05-09 Method of identifying precursor ions
EP21186501.9A EP3926659B1 (en) 2012-05-18 2013-05-09 Method of identifying precursor ions
GB1308297.9A GB2504373B (en) 2012-05-18 2013-05-09 Method of identifying precursor ions
EP13722022.4A EP2850636B1 (en) 2012-05-18 2013-05-09 Method of identifying precursor ions
US14/401,228 US9460902B2 (en) 2012-05-18 2013-05-09 Method of identifying precursor ions
US15/283,863 US10068754B2 (en) 2012-05-18 2016-10-03 Method of identifying precursor ions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1208961.1A GB201208961D0 (en) 2012-05-18 2012-05-18 2 dimensional MSMS

Publications (1)

Publication Number Publication Date
GB201208961D0 true GB201208961D0 (en) 2012-07-04

Family

ID=46546450

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1208961.1A Ceased GB201208961D0 (en) 2012-05-18 2012-05-18 2 dimensional MSMS
GB1308297.9A Active GB2504373B (en) 2012-05-18 2013-05-09 Method of identifying precursor ions

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1308297.9A Active GB2504373B (en) 2012-05-18 2013-05-09 Method of identifying precursor ions

Country Status (6)

Country Link
US (2) US9460902B2 (https=)
EP (2) EP2850636B1 (https=)
JP (1) JP6309508B2 (https=)
CA (1) CA2873610C (https=)
GB (2) GB201208961D0 (https=)
WO (1) WO2013171459A2 (https=)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201208961D0 (en) * 2012-05-18 2012-07-04 Micromass Ltd 2 dimensional MSMS
US9881778B2 (en) 2014-04-17 2018-01-30 Micromass Uk Limited Hybrid acquisition method incorporating multiple dissociation techniques
GB201406981D0 (en) * 2014-04-17 2014-06-04 Micromass Ltd Hybrid acquisition method incorporating electron transfer dissociation triggered from fast sequential 2D MS/MS collision induced dissociation
WO2015173562A1 (en) * 2014-05-13 2015-11-19 Micromass Uk Limited Multi-dimensional ion separation
US9947518B2 (en) 2014-05-30 2018-04-17 Micromass Uk Limited Combined tandem mass spectrometry and ion mobility mass spectrometry
GB201410346D0 (en) * 2014-06-11 2014-07-23 Micromass Ltd Two dimensional msms acquisition modes
WO2015189544A1 (en) * 2014-06-11 2015-12-17 Micromass Uk Limited Two dimensional ms/ms acquisition modes
US10495647B2 (en) * 2014-06-13 2019-12-03 Waters Technologies Corporation Analysis of complex biological matrices through targeting and advanced precursor and product ion alignment
WO2015193946A1 (ja) * 2014-06-16 2015-12-23 株式会社島津製作所 Ｍｓ／ｍｓ型質量分析方法及びｍｓ／ｍｓ型質量分析装置
CN106796654A (zh) * 2014-10-08 2017-05-31 Dh科技发展私人贸易有限公司 改进ida光谱输出用于数据库检索
JP6698668B2 (ja) * 2015-02-05 2020-05-27 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 断片化エネルギーを切り替えながらの幅広い四重極ｒｆ窓の高速スキャニング
US10861687B2 (en) * 2015-04-23 2020-12-08 Micromass Uk Limited Separating ions in an ion trap
EP3443580B1 (en) 2016-04-14 2024-07-17 Micromass UK Limited Two-dimensional msms
WO2018020363A1 (en) 2016-07-25 2018-02-01 Dh Technologies Development Pte. Ltd. Systems and methods for identifying precursor and product ion pairs in scanning swath data
US11069517B2 (en) * 2017-02-22 2021-07-20 Dh Technologies Development Pte. Ltd. Physical isolation of adducts and other complicating factors in precursor ion selection for IDA
GB2563565B (en) 2017-04-13 2022-05-11 Micromass Ltd Mass spectrometry with increased duty cycle
CN112640034B (zh) * 2018-09-06 2024-10-11 株式会社岛津制作所 四极质量分析装置
US10832897B2 (en) * 2018-10-19 2020-11-10 Thermo Finnigan Llc Methods and devices for high-throughput data independent analysis for mass spectrometry using parallel arrays of cells
CN113631920B (zh) 2019-05-31 2024-04-26 Dh科技发展私人贸易有限公司 用于前体推理的扫描带数据和概率框架的实时编码的方法
WO2022107026A2 (en) 2020-11-19 2022-05-27 Dh Technologies Development Pte. Ltd. Method of performing ms/ms of high intensity ion beams using a bandpass filtering collision cell to enhance mass spectrometry robustness
EP4352776A1 (en) 2021-06-09 2024-04-17 DH Technologies Development Pte. Ltd. Enhanced q1 mass segregation in scanning swath
US20250125133A1 (en) 2021-07-23 2025-04-17 Dh Technologies Development Pte. Ltd. Preventing Errors in Processing and Interpreting Mass Spectrometry Results
CN117795643A (zh) 2021-08-05 2024-03-29 Dh科技发展私人贸易有限公司 Tof-ms中的空间电荷减少
CN118043938A (zh) 2021-08-26 2024-05-14 Dh科技发展私人贸易有限公司 用于增强dda质谱法中的信息的方法
WO2023037248A1 (en) 2021-09-08 2023-03-16 Dh Technologies Development Pte. Ltd. Identification of changing pathways or disease indicators through cluster analysis
CN118525336A (zh) 2021-10-05 2024-08-20 Dh科技发展私人贸易有限公司 用于增强对dia数据的完整数据提取的方法
CN118556276A (zh) 2021-11-19 2024-08-27 Dh科技发展私人贸易有限公司 用于使用模拟检测系统进行降噪和离子速率估计的方法
EP4473537A1 (en) 2022-02-04 2024-12-11 DH Technologies Development Pte. Ltd. Compound identification using a mass spectrum
EP4508650A1 (en) 2022-04-12 2025-02-19 DH Technologies Development Pte. Ltd. Library search using deep learning based spectral compression
EP4508646A1 (en) 2022-04-12 2025-02-19 DH Technologies Development Pte. Ltd. Scoring of whole protein msms spectra based on a bond relevance score
US20250259697A1 (en) 2022-04-12 2025-08-14 Dh Technologies Development Pte. Ltd. Single Panel Representation of Multiple Charge Evidence Linked to a Bond in the Protein
US20260079140A1 (en) 2022-10-06 2026-03-19 Dh Technologies Development Pte. Ltd. Reducing Data Complexity for Subsequent RT Alignment
WO2024075065A1 (en) 2022-10-06 2024-04-11 Dh Technologies Development Pte. Ltd. Creation of realistic ms/ms spectra for putative designer drugs
WO2024121697A1 (en) 2022-12-07 2024-06-13 Dh Technologies Development Pte. Ltd. De novo sequencing of dna
WO2024150129A1 (en) 2023-01-09 2024-07-18 Dh Technologies Development Pte. Ltd. Sequencing of morpholino oligomers using electron capture dissociation
WO2024194801A1 (en) * 2023-03-22 2024-09-26 Dh Technologies Development Pte. Ltd. Multidimensional variable scanning swath mass spectrometry

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2340150C (en) 2000-06-09 2005-11-22 Micromass Limited Methods and apparatus for mass spectrometry
GB0305796D0 (en) * 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
US6992283B2 (en) 2003-06-06 2006-01-31 Micromass Uk Limited Mass spectrometer
JP4928724B2 (ja) * 2003-10-14 2012-05-09 マイクロマス ユーケー リミテッド 質量分析計
US8165820B2 (en) * 2005-06-03 2012-04-24 Waters Technologies Corporation Methods and apparatus for performing retention-time matching
US8105838B2 (en) * 2005-06-03 2012-01-31 Waters Technologies Corporation Generation and use of a catalog of polypeptide-related information for chemical analyses
GB2432712B (en) * 2005-11-23 2007-12-27 Micromass Ltd Mass spectrometer
JP5262010B2 (ja) * 2007-08-01 2013-08-14 株式会社日立製作所 質量分析計及び質量分析方法
JP5111123B2 (ja) * 2008-01-16 2012-12-26 株式会社日立製作所 質量分析計及び質量分析方法
JP5251232B2 (ja) * 2008-04-25 2013-07-31 株式会社島津製作所 質量分析データ処理方法及び質量分析装置
WO2009146345A1 (en) * 2008-05-29 2009-12-03 Waters Technologies Corporation Techniques for performing retention-time matching of precursor and product ions and for constructing precursor and product ion spectra
WO2010089798A1 (ja) * 2009-02-05 2010-08-12 株式会社島津製作所 Ｍｓ／ｍｓ型質量分析装置
EP2436025A1 (en) * 2009-05-27 2012-04-04 DH Technologies Development Pte. Ltd. Linear ion trap for msms
GB0909289D0 (en) * 2009-05-29 2009-07-15 Micromass Ltd Method of processing mass spectral data
GB0915474D0 (en) * 2009-09-04 2009-10-07 Micromass Ltd Multiple reaction monitoring with a time-of-flight based mass spectrometer
JP5454484B2 (ja) * 2011-01-31 2014-03-26 株式会社島津製作所 三連四重極型質量分析装置
GB201208961D0 (en) * 2012-05-18 2012-07-04 Micromass Ltd 2 dimensional MSMS
US10615014B2 (en) * 2013-11-12 2020-04-07 Micromass Uk Limited Data dependent MS/MS analysis

Also Published As

Publication number Publication date
GB2504373B (en) 2017-01-25
JP6309508B2 (ja) 2018-04-11
US10068754B2 (en) 2018-09-04
US20150136969A1 (en) 2015-05-21
CA2873610A1 (en) 2013-11-21
US20170125224A1 (en) 2017-05-04
GB2504373A (en) 2014-01-29
EP3926659B1 (en) 2025-07-30
EP2850636B1 (en) 2021-09-01
CA2873610C (en) 2020-03-24
EP3926659A1 (en) 2021-12-22
GB201308297D0 (en) 2013-06-12
WO2013171459A3 (en) 2014-06-26
WO2013171459A2 (en) 2013-11-21
EP2850636A2 (en) 2015-03-25
JP2015523550A (ja) 2015-08-13
US9460902B2 (en) 2016-10-04

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)