JP6309508B2 - 前駆イオンの同定方法 - Google Patents

前駆イオンの同定方法 Download PDF

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Publication number
JP6309508B2
JP6309508B2 JP2015512116A JP2015512116A JP6309508B2 JP 6309508 B2 JP6309508 B2 JP 6309508B2 JP 2015512116 A JP2015512116 A JP 2015512116A JP 2015512116 A JP2015512116 A JP 2015512116A JP 6309508 B2 JP6309508 B2 JP 6309508B2
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mass
ion
fragment
ions
precursor
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Japanese (ja)
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JP2015523550A5 (https=
JP2015523550A (ja
Inventor
ジェイソン リー ワイルドグース，
ジェイソン リー ワイルドグース，
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マイクロマス ユーケー リミテッド
マイクロマス ユーケー リミテッド
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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0031—Step by step routines describing the use of the apparatus
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H01J49/005—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction by collision with gas, e.g. by introducing gas or by accelerating ions with an electric field
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/40—Time-of-flight spectrometers

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
JP2015512116A 2012-05-18 2013-05-09 前駆イオンの同定方法 Active JP6309508B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB1208961.1 2012-05-18
GBGB1208961.1A GB201208961D0 (en) 2012-05-18 2012-05-18 2 dimensional MSMS
US201261649998P 2012-05-22 2012-05-22
US61/649,998 2012-05-22
PCT/GB2013/051199 WO2013171459A2 (en) 2012-05-18 2013-05-09 Method of identifying precursor ions

Publications (3)

Publication Number Publication Date
JP2015523550A JP2015523550A (ja) 2015-08-13
JP2015523550A5 JP2015523550A5 (https=) 2017-03-16
JP6309508B2 true JP6309508B2 (ja) 2018-04-11

Family

ID=46546450

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015512116A Active JP6309508B2 (ja) 2012-05-18 2013-05-09 前駆イオンの同定方法

Country Status (6)

Country Link
US (2) US9460902B2 (https=)
EP (2) EP2850636B1 (https=)
JP (1) JP6309508B2 (https=)
CA (1) CA2873610C (https=)
GB (2) GB201208961D0 (https=)
WO (1) WO2013171459A2 (https=)

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WO2015193946A1 (ja) * 2014-06-16 2015-12-23 株式会社島津製作所 Ｍｓ／ｍｓ型質量分析方法及びｍｓ／ｍｓ型質量分析装置
CN106796654A (zh) * 2014-10-08 2017-05-31 Dh科技发展私人贸易有限公司 改进ida光谱输出用于数据库检索
JP6698668B2 (ja) * 2015-02-05 2020-05-27 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 断片化エネルギーを切り替えながらの幅広い四重極ｒｆ窓の高速スキャニング
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WO2018020363A1 (en) 2016-07-25 2018-02-01 Dh Technologies Development Pte. Ltd. Systems and methods for identifying precursor and product ion pairs in scanning swath data
US11069517B2 (en) * 2017-02-22 2021-07-20 Dh Technologies Development Pte. Ltd. Physical isolation of adducts and other complicating factors in precursor ion selection for IDA
GB2563565B (en) 2017-04-13 2022-05-11 Micromass Ltd Mass spectrometry with increased duty cycle
CN112640034B (zh) * 2018-09-06 2024-10-11 株式会社岛津制作所 四极质量分析装置
US10832897B2 (en) * 2018-10-19 2020-11-10 Thermo Finnigan Llc Methods and devices for high-throughput data independent analysis for mass spectrometry using parallel arrays of cells
CN113631920B (zh) 2019-05-31 2024-04-26 Dh科技发展私人贸易有限公司 用于前体推理的扫描带数据和概率框架的实时编码的方法
WO2022107026A2 (en) 2020-11-19 2022-05-27 Dh Technologies Development Pte. Ltd. Method of performing ms/ms of high intensity ion beams using a bandpass filtering collision cell to enhance mass spectrometry robustness
EP4352776A1 (en) 2021-06-09 2024-04-17 DH Technologies Development Pte. Ltd. Enhanced q1 mass segregation in scanning swath
US20250125133A1 (en) 2021-07-23 2025-04-17 Dh Technologies Development Pte. Ltd. Preventing Errors in Processing and Interpreting Mass Spectrometry Results
CN117795643A (zh) 2021-08-05 2024-03-29 Dh科技发展私人贸易有限公司 Tof-ms中的空间电荷减少
CN118043938A (zh) 2021-08-26 2024-05-14 Dh科技发展私人贸易有限公司 用于增强dda质谱法中的信息的方法
WO2023037248A1 (en) 2021-09-08 2023-03-16 Dh Technologies Development Pte. Ltd. Identification of changing pathways or disease indicators through cluster analysis
CN118525336A (zh) 2021-10-05 2024-08-20 Dh科技发展私人贸易有限公司 用于增强对dia数据的完整数据提取的方法
CN118556276A (zh) 2021-11-19 2024-08-27 Dh科技发展私人贸易有限公司 用于使用模拟检测系统进行降噪和离子速率估计的方法
EP4473537A1 (en) 2022-02-04 2024-12-11 DH Technologies Development Pte. Ltd. Compound identification using a mass spectrum
EP4508650A1 (en) 2022-04-12 2025-02-19 DH Technologies Development Pte. Ltd. Library search using deep learning based spectral compression
EP4508646A1 (en) 2022-04-12 2025-02-19 DH Technologies Development Pte. Ltd. Scoring of whole protein msms spectra based on a bond relevance score
US20250259697A1 (en) 2022-04-12 2025-08-14 Dh Technologies Development Pte. Ltd. Single Panel Representation of Multiple Charge Evidence Linked to a Bond in the Protein
US20260079140A1 (en) 2022-10-06 2026-03-19 Dh Technologies Development Pte. Ltd. Reducing Data Complexity for Subsequent RT Alignment
WO2024075065A1 (en) 2022-10-06 2024-04-11 Dh Technologies Development Pte. Ltd. Creation of realistic ms/ms spectra for putative designer drugs
WO2024121697A1 (en) 2022-12-07 2024-06-13 Dh Technologies Development Pte. Ltd. De novo sequencing of dna
WO2024150129A1 (en) 2023-01-09 2024-07-18 Dh Technologies Development Pte. Ltd. Sequencing of morpholino oligomers using electron capture dissociation
WO2024194801A1 (en) * 2023-03-22 2024-09-26 Dh Technologies Development Pte. Ltd. Multidimensional variable scanning swath mass spectrometry

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JP5454484B2 (ja) * 2011-01-31 2014-03-26 株式会社島津製作所 三連四重極型質量分析装置
GB201208961D0 (en) * 2012-05-18 2012-07-04 Micromass Ltd 2 dimensional MSMS
US10615014B2 (en) * 2013-11-12 2020-04-07 Micromass Uk Limited Data dependent MS/MS analysis

Also Published As

Publication number Publication date
GB2504373B (en) 2017-01-25
US10068754B2 (en) 2018-09-04
US20150136969A1 (en) 2015-05-21
CA2873610A1 (en) 2013-11-21
GB201208961D0 (en) 2012-07-04
US20170125224A1 (en) 2017-05-04
GB2504373A (en) 2014-01-29
EP3926659B1 (en) 2025-07-30
EP2850636B1 (en) 2021-09-01
CA2873610C (en) 2020-03-24
EP3926659A1 (en) 2021-12-22
GB201308297D0 (en) 2013-06-12
WO2013171459A3 (en) 2014-06-26
WO2013171459A2 (en) 2013-11-21
EP2850636A2 (en) 2015-03-25
JP2015523550A (ja) 2015-08-13
US9460902B2 (en) 2016-10-04

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