GB2001644A - Preparation of Tobias Acid - Google Patents

Preparation of Tobias Acid

Info

Publication number
GB2001644A
GB2001644A GB787830888A GB7830888A GB2001644A GB 2001644 A GB2001644 A GB 2001644A GB 787830888 A GB787830888 A GB 787830888A GB 7830888 A GB7830888 A GB 7830888A GB 2001644 A GB2001644 A GB 2001644A
Authority
GB
United Kingdom
Prior art keywords
acid
tobias
tobias acid
reaction mixture
armstrong
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB787830888A
Other versions
GB2001644B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of GB2001644A publication Critical patent/GB2001644A/en
Application granted granted Critical
Publication of GB2001644B publication Critical patent/GB2001644B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/32—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of salts of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/42—Separation; Purification; Stabilisation; Use of additives
    • C07C303/44—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

A process for the preparing Tobias Acid (2-amino-1-naphthalene- sulfonic acid) from beta-naphthol is disclosed in which an intermediate reaction mixture containing Armstrong Acid (2-hydroxy-1-naphthalenesulfonic acid) is transferred to a holding vessel at about 0 DEG -10 DEG C. for about 5-60 minutes prior to carrying out the amination reaction which converts the Armstrong Acid to Tobias Acid, and in which also, later in the process after amination and extraction of the reaction mixture with a water-immiscible organic solvent, an extracted aqueous phase of alkali metal and ammonium salts of Tobias Acid is acidified to pH about 1.8-2.5 at about 20 DEG -80 DEG C. to form a slurry from which Tobias Acid can be recovered by cooling to about 20 to 45 DEG C.
GB787830888A 1977-07-29 1978-07-24 Process for the preparation of tobias acid Expired GB2001644B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82005777A 1977-07-29 1977-07-29

Publications (2)

Publication Number Publication Date
GB2001644A true GB2001644A (en) 1979-02-07
GB2001644B GB2001644B (en) 1982-02-10

Family

ID=25229775

Family Applications (1)

Application Number Title Priority Date Filing Date
GB787830888A Expired GB2001644B (en) 1977-07-29 1978-07-24 Process for the preparation of tobias acid

Country Status (4)

Country Link
JP (1) JPS5427554A (en)
DE (1) DE2831992A1 (en)
FR (1) FR2398724A1 (en)
GB (1) GB2001644B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4510100A (en) * 1979-12-20 1985-04-09 Ciba Geigy Ag Process for the production of 2-amino-1-naphthalenesulfonic acid

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2831993A1 (en) * 1977-07-29 1979-02-08 American Cyanamid Co PROCESS FOR THE PREPARATION OF 2-AMINO-1NAPHTHALINE SULPHONIC ACID
DE2831956A1 (en) * 1977-07-29 1979-02-15 American Cyanamid Co Process for the preparation of an aqueous solution of an alkali metal salt of 2-Hydroxy-1-NAPHTHALINE-SULPHONIC ACID
DE2831995A1 (en) * 1977-07-29 1979-02-08 American Cyanamid Co PROCESS FOR THE PREPARATION OF AN AQUATIC SOLUTION OF AN ALKALINE SALT OF 2-HYDROXY-1-NAPHTHALINE SULPHONIC ACID
DE2831994A1 (en) * 1977-07-29 1979-02-08 American Cyanamid Co PROCESS FOR PRODUCTION OF TOBIAC ACID
DE2831965A1 (en) * 1977-07-29 1979-02-08 American Cyanamid Co PROCESS FOR THE PREPARATION OF 2-AMINO- 1-NAPHTHALINE SULFONIC ACID

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2058911A (en) * 1931-12-08 1936-10-27 Nat Aniline & Chem Co Inc Process for the purification of naphthylamine sulphonic acid
FR1182010A (en) * 1956-09-05 1959-06-22 Gen Aniline & Film Corp Process for preparing beta-naphthol-sulfonic acid
DD103390A1 (en) * 1973-01-12 1974-01-20
CA1051023A (en) * 1975-03-14 1979-03-20 Henry X. Kaempfen Method for tobias acid manufacture
DE2831956A1 (en) * 1977-07-29 1979-02-15 American Cyanamid Co Process for the preparation of an aqueous solution of an alkali metal salt of 2-Hydroxy-1-NAPHTHALINE-SULPHONIC ACID
DE2831966A1 (en) * 1977-07-29 1979-02-08 American Cyanamid Co PROCESS FOR THE PREPARATION OF 2-AMINO- 1-NAPHTHALINE SULFONIC ACID
DE2831995A1 (en) * 1977-07-29 1979-02-08 American Cyanamid Co PROCESS FOR THE PREPARATION OF AN AQUATIC SOLUTION OF AN ALKALINE SALT OF 2-HYDROXY-1-NAPHTHALINE SULPHONIC ACID
DE2831994A1 (en) * 1977-07-29 1979-02-08 American Cyanamid Co PROCESS FOR PRODUCTION OF TOBIAC ACID
DE2831965A1 (en) * 1977-07-29 1979-02-08 American Cyanamid Co PROCESS FOR THE PREPARATION OF 2-AMINO- 1-NAPHTHALINE SULFONIC ACID

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4510100A (en) * 1979-12-20 1985-04-09 Ciba Geigy Ag Process for the production of 2-amino-1-naphthalenesulfonic acid

Also Published As

Publication number Publication date
FR2398724A1 (en) 1979-02-23
JPS5427554A (en) 1979-03-01
DE2831992A1 (en) 1979-02-08
GB2001644B (en) 1982-02-10

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee