GB1595020A - 3a-hydroxy steroid derivatives of the cholestane series - Google Patents

3a-hydroxy steroid derivatives of the cholestane series Download PDF

Info

Publication number
GB1595020A
GB1595020A GB25022/78A GB2502278A GB1595020A GB 1595020 A GB1595020 A GB 1595020A GB 25022/78 A GB25022/78 A GB 25022/78A GB 2502278 A GB2502278 A GB 2502278A GB 1595020 A GB1595020 A GB 1595020A
Authority
GB
United Kingdom
Prior art keywords
process according
reaction
carried out
chloride
mercuric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB25022/78A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP7452677A external-priority patent/JPS6039279B2/ja
Priority claimed from JP10059177A external-priority patent/JPS5436250A/ja
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of GB1595020A publication Critical patent/GB1595020A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
GB25022/78A 1977-06-24 1978-05-31 3a-hydroxy steroid derivatives of the cholestane series Expired GB1595020A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7452677A JPS6039279B2 (ja) 1977-06-24 1977-06-24 エピデスモステロ−ル誘導体
JP10059177A JPS5436250A (en) 1977-08-24 1977-08-24 25-hydroxyepicholesterol derivatives

Publications (1)

Publication Number Publication Date
GB1595020A true GB1595020A (en) 1981-08-05

Family

ID=26415681

Family Applications (1)

Application Number Title Priority Date Filing Date
GB25022/78A Expired GB1595020A (en) 1977-06-24 1978-05-31 3a-hydroxy steroid derivatives of the cholestane series

Country Status (4)

Country Link
US (1) US4225524A (enExample)
DE (1) DE2827445A1 (enExample)
FR (1) FR2397427A1 (enExample)
GB (1) GB1595020A (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997042215A1 (en) * 1996-05-06 1997-11-13 Bionumerik Pharmaceuticals, Inc. Process for preparing 27-hydroxy cholesterol and related derivatives
US8399441B2 (en) * 2004-10-25 2013-03-19 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of lipid homeostasis, for therapy of hypercholesterolemia, hypertriglycerides, fatty liver diseases, and atherosclerosis
WO2006047022A1 (en) 2004-10-25 2006-05-04 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of cholesterol homeostasis, for therapy of hypercholesterolemia, hyperlipidemia, and atherosclerosis
US9034859B2 (en) 2011-04-06 2015-05-19 Virginia Commonwealth University Sulfated oxysterol and oxysterol sulfation by hydroxysterol sulfotransferase promote lipid homeostasis and liver proliferation
EP3086793B1 (en) 2013-12-24 2022-05-11 Virginia Commonwealth University Use of oxygenated cholesterol sulfates (ocs) for the treatment of kidney dysfunction
KR102593667B1 (ko) 2016-08-02 2023-10-24 버지니아 커먼웰스 유니버시티 5-콜레스텐-3, 25-디올, 3-술페이트 (25hc3s) 또는 이의 약학적으로 허용 가능한 염, 및 적어도 하나의 시클릭 올리고당을 포함하는 조성물

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846455A (en) * 1972-05-22 1974-11-05 Eisai Co Ltd Process for the preparation of 25-hydroxy-cholesterol and esters thereof
JPS5218700B2 (enExample) * 1973-02-16 1977-05-24
GB1447456A (en) * 1973-06-20 1976-08-25 Teijin Ltd Process for preparing desmosterols
JPS50149662A (enExample) * 1974-05-22 1975-11-29

Also Published As

Publication number Publication date
FR2397427A1 (fr) 1979-02-09
FR2397427B1 (enExample) 1982-03-26
DE2827445A1 (de) 1979-03-22
US4225524A (en) 1980-09-30

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee