GB1577670A - 1-aryloxy-2 - hydroxy - 3 - aminopropanes and process for their preparation - Google Patents

1-aryloxy-2 - hydroxy - 3 - aminopropanes and process for their preparation Download PDF

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Publication number
GB1577670A
GB1577670A GB22051/77A GB2205177A GB1577670A GB 1577670 A GB1577670 A GB 1577670A GB 22051/77 A GB22051/77 A GB 22051/77A GB 2205177 A GB2205177 A GB 2205177A GB 1577670 A GB1577670 A GB 1577670A
Authority
GB
United Kingdom
Prior art keywords
phenyl
radical
grams
propoxy
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB22051/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of GB1577670A publication Critical patent/GB1577670A/en
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyridine Compounds (AREA)
GB22051/77A 1976-05-25 1977-05-25 1-aryloxy-2 - hydroxy - 3 - aminopropanes and process for their preparation Expired GB1577670A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2623314A DE2623314C2 (de) 1976-05-25 1976-05-25 1-Aryloxy-2-Hydroxy-3-aminopropane, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
GB1577670A true GB1577670A (en) 1980-10-29

Family

ID=5978907

Family Applications (1)

Application Number Title Priority Date Filing Date
GB22051/77A Expired GB1577670A (en) 1976-05-25 1977-05-25 1-aryloxy-2 - hydroxy - 3 - aminopropanes and process for their preparation

Country Status (18)

Country Link
JP (1) JPS5312827A (no)
AT (1) AT354421B (no)
AU (1) AU511704B2 (no)
BE (1) BE855041A (no)
CA (1) CA1108633A (no)
CH (5) CH637105A5 (no)
DE (1) DE2623314C2 (no)
DK (1) DK227177A (no)
ES (1) ES458957A1 (no)
FI (1) FI67698C (no)
FR (1) FR2353520A1 (no)
GB (1) GB1577670A (no)
HU (1) HU179198B (no)
IL (1) IL52148A (no)
IT (1) IT1077193B (no)
NL (1) NL7705587A (no)
SE (1) SE440903B (no)
ZA (1) ZA773120B (no)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001016124A1 (de) * 1999-09-01 2001-03-08 Dr. Willmar Schwabe Gmbh & Co. Zimtsäurenitrile, verfahren zu ihrer herstellung und verwendung

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2415622A1 (fr) * 1978-01-25 1979-08-24 Lipha Amino alcools derives de l'ortho-hydroxy cinnamate de methyle applicables notamment comme medicaments
DE2824764A1 (de) * 1978-06-06 1979-12-20 Hoechst Ag Neue pyridylpiperazinderivate und verfahren zu ihrer herstellung
IT1118835B (it) * 1978-08-15 1986-03-03 Smithkline Corp Procedimento per introdurre catene laterali di bloccaggio in nuclei aromatici contenenti un gruppo fenolico
FR2459235A1 (fr) * 1979-06-14 1981-01-09 Sanofi Sa Nouveaux derives de sulfonyl-aniline, leur procede de preparation et leur application therapeutique
JPH0629833B2 (ja) * 1984-06-15 1994-04-20 株式会社島津製作所 疲労試験機
GB8603120D0 (en) * 1986-02-07 1986-03-12 Pfizer Ltd Anti-dysrhythmia agents
CA2716369C (en) 1999-05-24 2013-05-14 Mitsubishi Tanabe Pharma Corporation Phenoxypropylamine compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA945172A (en) * 1969-02-21 1974-04-09 Imperial Chemical Industries Limited Alkanolamine derivatives
FR2132570B1 (no) * 1971-04-09 1974-08-02 Lipha
BE791650R (fr) * 1971-11-18 1973-05-21 Ici Ltd Derives d'alkanolamines.
ES411826A1 (es) * 1973-02-20 1976-01-01 Liade Sa Lab Procedimiento de obtencion de 1-ariloxi - 2 - propanolami- nas farmacologicamente activos.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001016124A1 (de) * 1999-09-01 2001-03-08 Dr. Willmar Schwabe Gmbh & Co. Zimtsäurenitrile, verfahren zu ihrer herstellung und verwendung

Also Published As

Publication number Publication date
CH637108A5 (en) 1983-07-15
AU511704B2 (en) 1980-09-04
BE855041A (fr) 1977-11-25
FR2353520A1 (fr) 1977-12-30
FR2353520B1 (no) 1980-07-25
AT354421B (de) 1979-01-10
CH637105A5 (en) 1983-07-15
FI771630A (no) 1977-11-26
SE440903B (sv) 1985-08-26
CH640507A5 (en) 1984-01-13
JPS5312827A (en) 1978-02-04
AU2543477A (en) 1978-11-30
CH637109A5 (en) 1983-07-15
CA1108633A (en) 1981-09-08
ZA773120B (en) 1978-04-26
FI67698B (fi) 1985-01-31
IL52148A0 (en) 1977-07-31
DE2623314A1 (de) 1977-12-08
JPS6214545B2 (no) 1987-04-02
ATA370177A (de) 1979-06-15
NL7705587A (nl) 1977-11-29
DE2623314C2 (de) 1984-08-02
ES458957A1 (es) 1978-07-16
FI67698C (fi) 1985-05-10
SE7706059L (sv) 1977-11-26
HU179198B (en) 1982-09-28
IT1077193B (it) 1985-05-04
DK227177A (da) 1977-11-26
CH637107A5 (en) 1983-07-15
IL52148A (en) 1982-07-30

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
746 Register noted 'licences of right' (sect. 46/1977)
PCNP Patent ceased through non-payment of renewal fee