GB1555890A - Optically active n substituted pyrrolidines - Google Patents

Optically active n substituted pyrrolidines

Info

Publication number
GB1555890A
GB1555890A GB32790/77A GB3279077A GB1555890A GB 1555890 A GB1555890 A GB 1555890A GB 32790/77 A GB32790/77 A GB 32790/77A GB 3279077 A GB3279077 A GB 3279077A GB 1555890 A GB1555890 A GB 1555890A
Authority
GB
United Kingdom
Prior art keywords
optically active
reduction
formula
image
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB32790/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7623910A external-priority patent/FR2360572A1/fr
Priority claimed from FR7635476A external-priority patent/FR2372157A1/fr
Priority claimed from FR7719391A external-priority patent/FR2395261A2/fr
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of GB1555890A publication Critical patent/GB1555890A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB32790/77A 1976-08-05 1977-08-04 Optically active n substituted pyrrolidines Expired GB1555890A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7623910A FR2360572A1 (fr) 1976-08-05 1976-08-05 Pyrrolidines substituees et leur preparation
FR7635476A FR2372157A1 (fr) 1976-11-25 1976-11-25 Procede de synthese stereospecifique de n-alkyl- pyrrolidines optiquement actives
FR7719391A FR2395261A2 (fr) 1977-06-24 1977-06-24 Pyrrolidines substituees et leur preparation

Publications (1)

Publication Number Publication Date
GB1555890A true GB1555890A (en) 1979-11-14

Family

ID=27250658

Family Applications (1)

Application Number Title Priority Date Filing Date
GB32790/77A Expired GB1555890A (en) 1976-08-05 1977-08-04 Optically active n substituted pyrrolidines

Country Status (20)

Country Link
JP (1) JPS5325563A (enrdf_load_stackoverflow)
AT (1) AT364818B (enrdf_load_stackoverflow)
AU (1) AU510454B2 (enrdf_load_stackoverflow)
CA (1) CA1083586A (enrdf_load_stackoverflow)
CH (2) CH624933A5 (enrdf_load_stackoverflow)
DE (1) DE2735036C2 (enrdf_load_stackoverflow)
DK (1) DK350377A (enrdf_load_stackoverflow)
ES (1) ES461342A1 (enrdf_load_stackoverflow)
FI (1) FI772363A7 (enrdf_load_stackoverflow)
GB (1) GB1555890A (enrdf_load_stackoverflow)
GR (1) GR63594B (enrdf_load_stackoverflow)
IE (1) IE45544B1 (enrdf_load_stackoverflow)
IL (1) IL52645A (enrdf_load_stackoverflow)
IT (1) IT1085696B (enrdf_load_stackoverflow)
LU (1) LU77917A1 (enrdf_load_stackoverflow)
NL (1) NL7708571A (enrdf_load_stackoverflow)
NO (2) NO772745L (enrdf_load_stackoverflow)
NZ (1) NZ184832A (enrdf_load_stackoverflow)
PT (1) PT66894B (enrdf_load_stackoverflow)
SE (2) SE7708902L (enrdf_load_stackoverflow)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0053584A1 (en) * 1980-11-27 1982-06-09 RAVIZZA S.p.A. Raceme sulpiride resolution process
EP0253785B1 (en) * 1986-05-22 1992-11-11 Astra Lakemedel Aktiebolag Efficient stereoconservative syntheses of 1-substituted (s)- and (r)-2-aminomethylpyrrolidines and intermediates therein
EP1566376A1 (en) * 2004-02-18 2005-08-24 Dr. Reddy's Laboratories Limited Preparation of amino acid amides
CN106045869A (zh) * 2016-06-30 2016-10-26 宜兴市前成生物有限公司 一种制备dl‑谷氨酸的方法
CN117185977A (zh) * 2023-09-20 2023-12-08 江苏阿尔法药业股份有限公司 一种氨磺必利中间体的制备方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1095415B (it) * 1978-02-16 1985-08-10 Ravizza Spa Processo per la produzione di una benzamide otticamente attiva,benzamide otticamente attiva cosi'ottenuta e composizioni
DE4425070A1 (de) 1994-07-15 1996-01-18 Degussa Verfahren zur Herstellung optisch aktiver l-substituierter 2-(Aminomethyl)pyrrolidine
CN104086475B (zh) * 2014-07-15 2016-10-05 苏州天马精细化学品股份有限公司 一种n-苄氧羰基-l-脯氨酰胺的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1528014A (fr) * 1967-04-24 1968-06-07 Ile De France Procédé de préparation des isomères optiques de la éthyl-1, aminométhyl-2-pyrrolidine
CH507938A (fr) * 1968-08-01 1971-05-31 Ile De France Procédé de préparation de benzamides hétérocycliques

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0053584A1 (en) * 1980-11-27 1982-06-09 RAVIZZA S.p.A. Raceme sulpiride resolution process
EP0253785B1 (en) * 1986-05-22 1992-11-11 Astra Lakemedel Aktiebolag Efficient stereoconservative syntheses of 1-substituted (s)- and (r)-2-aminomethylpyrrolidines and intermediates therein
EP1566376A1 (en) * 2004-02-18 2005-08-24 Dr. Reddy's Laboratories Limited Preparation of amino acid amides
CN106045869A (zh) * 2016-06-30 2016-10-26 宜兴市前成生物有限公司 一种制备dl‑谷氨酸的方法
CN117185977A (zh) * 2023-09-20 2023-12-08 江苏阿尔法药业股份有限公司 一种氨磺必利中间体的制备方法

Also Published As

Publication number Publication date
AU2764177A (en) 1979-02-08
CA1083586A (en) 1980-08-12
IL52645A (en) 1980-02-29
CH626341A5 (en) 1981-11-13
IT1085696B (it) 1985-05-28
LU77917A1 (enrdf_load_stackoverflow) 1977-11-14
PT66894B (fr) 1979-01-26
FI772363A7 (enrdf_load_stackoverflow) 1978-02-06
ES461342A1 (es) 1978-06-01
DE2735036C2 (de) 1983-10-13
NO772745L (no) 1978-02-07
NO812871L (no) 1978-02-07
DE2735036A1 (de) 1978-02-16
GR63594B (en) 1979-11-26
IE45544B1 (en) 1982-09-22
NL7708571A (nl) 1978-02-07
IE45544L (en) 1978-02-05
ATA577377A (de) 1981-04-15
AT364818B (de) 1981-11-25
SE8009074L (sv) 1980-12-22
AU510454B2 (en) 1980-06-26
IL52645A0 (en) 1977-10-31
DK350377A (da) 1978-02-06
JPS5325563A (en) 1978-03-09
PT66894A (fr) 1977-09-01
CH624933A5 (enrdf_load_stackoverflow) 1981-08-31
NZ184832A (en) 1979-11-01
SE7708902L (sv) 1978-02-06

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee