GB1525434A - Anti-inflammatory thiophene derivatives - Google Patents

Anti-inflammatory thiophene derivatives

Info

Publication number
GB1525434A
GB1525434A GB31852/76A GB3185276A GB1525434A GB 1525434 A GB1525434 A GB 1525434A GB 31852/76 A GB31852/76 A GB 31852/76A GB 3185276 A GB3185276 A GB 3185276A GB 1525434 A GB1525434 A GB 1525434A
Authority
GB
United Kingdom
Prior art keywords
inflammatory
formula
thiophene derivatives
compounds
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB31852/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA283,755A priority Critical patent/CA1078400A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Priority to GB31852/76A priority patent/GB1525434A/en
Priority to IL52503A priority patent/IL52503A/xx
Priority to ZA00774222A priority patent/ZA774222B/xx
Priority to NL7708062A priority patent/NL7708062A/xx
Priority to CH919577A priority patent/CH636613A5/de
Priority to FR7722739A priority patent/FR2359837A1/fr
Priority to BE179615A priority patent/BE857128A/xx
Priority to DE19772733683 priority patent/DE2733683A1/de
Priority to SE7708591A priority patent/SE7708591L/xx
Priority to ES461037A priority patent/ES461037A1/es
Priority to DK339877A priority patent/DK339877A/da
Priority to JP9053877A priority patent/JPS5318558A/ja
Priority to AT560477A priority patent/AT361466B/de
Priority to AU27471/77A priority patent/AU507121B2/en
Priority to IE1585/77A priority patent/IE45325B1/en
Priority to US05/927,394 priority patent/US4153718A/en
Publication of GB1525434A publication Critical patent/GB1525434A/en
Priority to US05/952,390 priority patent/US4198519A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Rheumatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB31852/76A 1976-07-30 1976-07-30 Anti-inflammatory thiophene derivatives Expired GB1525434A (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
CA283,755A CA1078400A (en) 1976-07-30 1976-07-29 Anti-inflammatory compounds
GB31852/76A GB1525434A (en) 1976-07-30 1976-07-30 Anti-inflammatory thiophene derivatives
IL52503A IL52503A (en) 1976-07-30 1977-07-11 4-(thienoyl)phenyl alkanone derivatives,their preparation and pharmaceutical compositions containing them
ZA00774222A ZA774222B (en) 1976-07-30 1977-07-14 Anti-inflammatory compounds
NL7708062A NL7708062A (nl) 1976-07-30 1977-07-20 Werkwijze voor het bereiden van nieuwe thio- feenderivaten met anti-inflammatoire werking, alsmede gedoseerde farmaceutische preparaten die deze verbindingen bevatten.
CH919577A CH636613A5 (en) 1976-07-30 1977-07-25 Process for preparing thiophene derivatives
FR7722739A FR2359837A1 (fr) 1976-07-30 1977-07-25 Nouveaux derives du thiophene ayant une activite anti-inflammatoire
BE179615A BE857128A (fr) 1976-07-30 1977-07-25 Nouveaux derives du thiophene
SE7708591A SE7708591L (sv) 1976-07-30 1977-07-26 Foreningar med antiinflammatorisk verkan
DE19772733683 DE2733683A1 (de) 1976-07-30 1977-07-26 Thiophen-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate
ES461037A ES461037A1 (es) 1976-07-30 1977-07-26 Un procedimiento para la preparacion de derivados tiofeno.
DK339877A DK339877A (da) 1976-07-30 1977-07-27 Fremgangsmade til fremstilling af antiinflammatorisk virksomme forbindeler
JP9053877A JPS5318558A (en) 1976-07-30 1977-07-29 Thiophene derivatives* their preparation and medical composition containing same
AT560477A AT361466B (de) 1976-07-30 1977-07-29 Verfahren zur herstellung von neuen tiophen- derivaten
AU27471/77A AU507121B2 (en) 1976-07-30 1977-07-29 Thiophenes
IE1585/77A IE45325B1 (en) 1976-07-30 1977-07-29 Anti-inflammatory thiophene derivatives
US05/927,394 US4153718A (en) 1976-07-30 1978-07-24 Anti-inflammatory compounds
US05/952,390 US4198519A (en) 1976-07-30 1978-10-18 Anti-inflammatory compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB31852/76A GB1525434A (en) 1976-07-30 1976-07-30 Anti-inflammatory thiophene derivatives

Publications (1)

Publication Number Publication Date
GB1525434A true GB1525434A (en) 1978-09-20

Family

ID=10329363

Family Applications (1)

Application Number Title Priority Date Filing Date
GB31852/76A Expired GB1525434A (en) 1976-07-30 1976-07-30 Anti-inflammatory thiophene derivatives

Country Status (16)

Country Link
JP (1) JPS5318558A (enrdf_load_stackoverflow)
AT (1) AT361466B (enrdf_load_stackoverflow)
AU (1) AU507121B2 (enrdf_load_stackoverflow)
BE (1) BE857128A (enrdf_load_stackoverflow)
CA (1) CA1078400A (enrdf_load_stackoverflow)
CH (1) CH636613A5 (enrdf_load_stackoverflow)
DE (1) DE2733683A1 (enrdf_load_stackoverflow)
DK (1) DK339877A (enrdf_load_stackoverflow)
ES (1) ES461037A1 (enrdf_load_stackoverflow)
FR (1) FR2359837A1 (enrdf_load_stackoverflow)
GB (1) GB1525434A (enrdf_load_stackoverflow)
IE (1) IE45325B1 (enrdf_load_stackoverflow)
IL (1) IL52503A (enrdf_load_stackoverflow)
NL (1) NL7708062A (enrdf_load_stackoverflow)
SE (1) SE7708591L (enrdf_load_stackoverflow)
ZA (1) ZA774222B (enrdf_load_stackoverflow)

Also Published As

Publication number Publication date
AU507121B2 (en) 1980-02-07
FR2359837A1 (fr) 1978-02-24
NL7708062A (nl) 1978-02-01
DE2733683A1 (de) 1978-02-02
IE45325B1 (en) 1982-07-28
ES461037A1 (es) 1978-12-01
CA1078400A (en) 1980-05-27
IL52503A (en) 1981-06-29
JPS5318558A (en) 1978-02-20
ZA774222B (en) 1978-06-28
BE857128A (fr) 1978-01-25
ATA560477A (de) 1980-08-15
IL52503A0 (en) 1977-10-31
CH636613A5 (en) 1983-06-15
DK339877A (da) 1978-01-31
AU2747177A (en) 1979-02-01
FR2359837B1 (enrdf_load_stackoverflow) 1980-04-04
IE45325L (en) 1978-01-30
SE7708591L (sv) 1978-01-31
AT361466B (de) 1981-03-10

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee