IE45606L - Prostanoic acid derivatives - Google Patents
Prostanoic acid derivativesInfo
- Publication number
- IE45606L IE45606L IE771305A IE130577A IE45606L IE 45606 L IE45606 L IE 45606L IE 771305 A IE771305 A IE 771305A IE 130577 A IE130577 A IE 130577A IE 45606 L IE45606 L IE 45606L
- Authority
- IE
- Ireland
- Prior art keywords
- acid derivatives
- prostanoic acid
- compounds
- prostane
- gb1588157a
- Prior art date
Links
- WGJJROVFWIXTPA-OALUTQOASA-N prostanoic acid Chemical class CCCCCCCC[C@H]1CCC[C@@H]1CCCCCCC(O)=O WGJJROVFWIXTPA-OALUTQOASA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- UKVVPDHLUHAJNZ-PMACEKPBSA-N prostane Chemical class CCCCCCCC[C@H]1CCC[C@@H]1CCCCCCC UKVVPDHLUHAJNZ-PMACEKPBSA-N 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
Abstract
Novel prostane derivatives of the formula <IMAGE> in which the substituents are defined in Claim 1, are prepared. These compounds are obtained by reacting a corresponding prostane derivative, which has the carboxyl group in the 1 position, with an isocyanate, resulting in the introduction of the radical -NHR1. The compounds which are obtained can be used for the same pharmacological purposes as the natural prostaglandins.
[GB1588157A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762629834 DE2629834A1 (en) | 1976-06-30 | 1976-06-30 | NEW PROSTANIC ACID DERIVATIVES AND METHOD FOR THEIR PRODUCTION |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE45606L true IE45606L (en) | 1977-12-30 |
| IE45606B1 IE45606B1 (en) | 1982-10-06 |
Family
ID=5982096
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1305/77A IE45606B1 (en) | 1976-06-30 | 1977-06-27 | Prostanoic acid derivatives and processes for their preparation |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS537648A (en) |
| BE (1) | BE856326A (en) |
| CH (2) | CH632492A5 (en) |
| DE (1) | DE2629834A1 (en) |
| DK (1) | DK292777A (en) |
| FR (1) | FR2356636A1 (en) |
| GB (1) | GB1588157A (en) |
| IE (1) | IE45606B1 (en) |
| IT (1) | IT1114813B (en) |
| LU (1) | LU77648A1 (en) |
| NL (1) | NL7706588A (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0022443B1 (en) * | 1979-07-17 | 1984-09-26 | Pfizer Inc. | N-alkanesulfonyl 16,16-dimethyl-17-oxaprostaglandin carboxamides |
| US4292445A (en) * | 1980-04-28 | 1981-09-29 | The Upjohn Company | Amide and sulfonamide derivatives of 2-decarboxy-2-aminomethyl-PG-type compounds |
| JPS6033429B2 (en) * | 1980-04-28 | 1985-08-02 | 小野薬品工業株式会社 | Prostaglandin-like compounds |
| JPS6127087A (en) * | 1984-07-16 | 1986-02-06 | 株式会社東芝 | Induction heating cooking device |
| US5385945A (en) * | 1992-10-21 | 1995-01-31 | Allergan, Inc. | 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amides, and method of lowering intraocular pressure in the eye of a mammal by administration of these novel compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1440361A (en) | 1972-07-24 | 1976-06-23 | American Cyanamid Co | 11-deoxyprostaglandins of the e and f series and the preparation thereof |
| IE43462B1 (en) * | 1975-06-23 | 1981-03-11 | Pfizer | Substituted tetranorprostaglandins |
-
1976
- 1976-06-30 DE DE19762629834 patent/DE2629834A1/en not_active Withdrawn
-
1977
- 1977-06-15 NL NL7706588A patent/NL7706588A/en not_active Application Discontinuation
- 1977-06-27 IE IE1305/77A patent/IE45606B1/en unknown
- 1977-06-28 IT IT7725122A patent/IT1114813B/en active
- 1977-06-28 CH CH794777A patent/CH632492A5/en not_active IP Right Cessation
- 1977-06-28 LU LU77648A patent/LU77648A1/xx unknown
- 1977-06-29 GB GB27188/77A patent/GB1588157A/en not_active Expired
- 1977-06-30 FR FR7720092A patent/FR2356636A1/en active Granted
- 1977-06-30 JP JP7845177A patent/JPS537648A/en active Pending
- 1977-06-30 BE BE178963A patent/BE856326A/en not_active IP Right Cessation
- 1977-06-30 DK DK292777A patent/DK292777A/en not_active Application Discontinuation
-
1981
- 1981-10-16 CH CH664281A patent/CH632493A5/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2356636A1 (en) | 1978-01-27 |
| NL7706588A (en) | 1978-01-03 |
| FR2356636B1 (en) | 1980-04-25 |
| JPS537648A (en) | 1978-01-24 |
| IT1114813B (en) | 1986-01-27 |
| CH632493A5 (en) | 1982-10-15 |
| IE45606B1 (en) | 1982-10-06 |
| BE856326A (en) | 1977-12-30 |
| LU77648A1 (en) | 1977-10-10 |
| CH632492A5 (en) | 1982-10-15 |
| DE2629834A1 (en) | 1978-01-12 |
| GB1588157A (en) | 1981-04-15 |
| DK292777A (en) | 1977-12-31 |
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