IE45631L - 4-hydroxyphenylalkanolamine derivatives. - Google Patents

4-hydroxyphenylalkanolamine derivatives.

Info

Publication number
IE45631L
IE45631L IE771297A IE129777A IE45631L IE 45631 L IE45631 L IE 45631L IE 771297 A IE771297 A IE 771297A IE 129777 A IE129777 A IE 129777A IE 45631 L IE45631 L IE 45631L
Authority
IE
Ireland
Prior art keywords
hydroxyphenylalkanolamine
derivatives
compounds
gb1544872a
substituents
Prior art date
Application number
IE771297A
Other versions
IE45631B1 (en
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of IE45631L publication Critical patent/IE45631L/en
Publication of IE45631B1 publication Critical patent/IE45631B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The compounds of formula <IMAGE> in which the substituents have the meaning as defined in Claim 1, are prepared by reducing a corresponding compound having a keto group. The compounds thus produced are particularly useful as antihypertensive agent. [GB1544872A]
IE1297/77A 1976-06-25 1977-06-24 4-hydroxyphenylalkanolamine derivatives and preparation thereof IE45631B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69985676A 1976-06-25 1976-06-25
US80337277A 1977-06-03 1977-06-03

Publications (2)

Publication Number Publication Date
IE45631L true IE45631L (en) 1977-12-25
IE45631B1 IE45631B1 (en) 1982-10-20

Family

ID=27106508

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1297/77A IE45631B1 (en) 1976-06-25 1977-06-24 4-hydroxyphenylalkanolamine derivatives and preparation thereof

Country Status (21)

Country Link
JP (1) JPS5321134A (en)
AR (2) AR220896A1 (en)
AT (1) AT354420B (en)
AU (1) AU512626B2 (en)
CA (1) CA1091245A (en)
CH (2) CH627447A5 (en)
DE (1) DE2728641A1 (en)
DK (1) DK146386C (en)
ES (1) ES460040A1 (en)
FI (1) FI771976A (en)
FR (1) FR2366272A1 (en)
GB (1) GB1544872A (en)
HK (1) HK60184A (en)
IE (1) IE45631B1 (en)
IL (1) IL52353A (en)
LU (1) LU77604A1 (en)
NL (1) NL7707128A (en)
NO (1) NO144848C (en)
PH (2) PH15041A (en)
PT (1) PT66713B (en)
SE (1) SE7707341L (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4410548A (en) 1980-07-09 1983-10-18 Reckitt & Colman Products Limited Propanolamine derivatives
DE3128117A1 (en) * 1980-07-29 1982-03-11 Yamanouchi Pharmaceutical Co., Ltd., Tokyo NEW PHENYL-AETHYLAMINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF
FR2623804B1 (en) * 1987-11-27 1990-03-23 Elf Aquitaine PHENOL ACYLATION
AU620573B2 (en) * 1987-11-27 1992-02-20 Societe Nationale Elf Aquitaine Process for phenol alkylthiolation and its application to the synthesis of 4-acyl-2-alkylthiophenols
US5101065A (en) * 1991-02-04 1992-03-31 Imperial Chemical Industries Plc Acetophenone intermediates
ES2146709T3 (en) 1991-08-21 2000-08-16 Smith & Nephew Inc FLUID CONTROL SYSTEM.
WO1999037294A2 (en) 1998-01-26 1999-07-29 Mitokor Mitochondria protecting agents for treating mitochondria associated diseases
DE60008697T2 (en) * 2000-03-28 2005-02-10 Council Of Scientific And Industrial Research Process for the preparation of 4- (P-methoxyphenyl) -2-amino-butanes and insecticides
ES2362998T3 (en) 2002-08-19 2011-07-18 Pfizer Inc. COMBINATION THERAPY FOR HYPERPROLIFERATIVE DISEASES.
GT200600381A (en) 2005-08-25 2007-03-28 ORGANIC COMPOUNDS
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
CN101663262B (en) 2006-12-01 2014-03-26 百时美施贵宝公司 N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases
TWI545109B (en) * 2009-05-19 2016-08-11 本州化學工業有限公司 4-acylarakylphenol and derivatives thereof
EP2986599A1 (en) 2013-04-17 2016-02-24 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
CN104324977A (en) * 2014-10-22 2015-02-04 无锡市得力手机械有限公司 Wire unloading trolley of inverted wire drawing machine
HU231124B1 (en) * 2016-02-10 2020-12-28 Egis Gyógyszergyár Zrt. Method for producing morphologically homogenous mirabegron and mirabegron monohydrochloride
CA3125765A1 (en) 2019-01-18 2020-07-23 Astrazeneca Ab Pcsk9 inhibitors and methods of use thereof

Also Published As

Publication number Publication date
PH15041A (en) 1982-05-20
AT354420B (en) 1979-01-10
DE2728641A1 (en) 1978-01-05
LU77604A1 (en) 1978-02-01
AR220896A1 (en) 1980-12-15
PT66713A (en) 1977-07-01
AU512626B2 (en) 1980-10-23
JPS5321134A (en) 1978-02-27
DK146386B (en) 1983-09-26
IE45631B1 (en) 1982-10-20
PH14332A (en) 1981-05-29
NL7707128A (en) 1977-12-28
FR2366272A1 (en) 1978-04-28
NO144848C (en) 1981-11-25
PT66713B (en) 1978-11-21
DK281777A (en) 1977-12-26
NO144848B (en) 1981-08-17
IL52353A0 (en) 1977-08-31
CA1091245A (en) 1980-12-09
AR227126A1 (en) 1982-09-30
DK146386C (en) 1984-03-12
AU2636877A (en) 1979-01-04
ATA449377A (en) 1979-06-15
CH630068A5 (en) 1982-05-28
IL52353A (en) 1981-07-31
FI771976A (en) 1977-12-26
FR2366272B1 (en) 1981-03-06
ES460040A1 (en) 1978-05-01
SE7707341L (en) 1978-02-13
CH627447A5 (en) 1982-01-15
NO772245L (en) 1977-12-28
HK60184A (en) 1984-08-10
GB1544872A (en) 1979-04-25

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