GB1516947A - Hentricontapeptides - Google Patents
HentricontapeptidesInfo
- Publication number
- GB1516947A GB1516947A GB17691/76A GB1769176A GB1516947A GB 1516947 A GB1516947 A GB 1516947A GB 17691/76 A GB17691/76 A GB 17691/76A GB 1769176 A GB1769176 A GB 1769176A GB 1516947 A GB1516947 A GB 1516947A
- Authority
- GB
- United Kingdom
- Prior art keywords
- bzl
- thr
- boc
- gly
- pro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108010089804 glycyl-threonine Proteins 0.000 abstract 9
- 108010004914 prolylarginine Proteins 0.000 abstract 7
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- DMBKPDOAQVGTST-GFCCVEGCSA-N (2r)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylmethoxypropanoic acid Chemical compound CC(C)(C)OC(=O)N[C@@H](C(O)=O)COCC1=CC=CC=C1 DMBKPDOAQVGTST-GFCCVEGCSA-N 0.000 abstract 3
- CTXPLTPDOISPTE-YPMHNXCESA-N (2s,3r)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylmethoxybutanoic acid Chemical compound CC(C)(C)OC(=O)N[C@H](C(O)=O)[C@@H](C)OCC1=CC=CC=C1 CTXPLTPDOISPTE-YPMHNXCESA-N 0.000 abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- XEJHSOREGRDIEV-IRXDYDNUSA-N (2s)-2-[[(2s)-4-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoyl]amino]-3-phenylmethoxypropanoic acid Chemical compound CC(C)(C)OC(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(O)=O)COCC1=CC=CC=C1 XEJHSOREGRDIEV-IRXDYDNUSA-N 0.000 abstract 1
- CNBUSIJNWNXLQQ-NSHDSACASA-N (2s)-3-(4-hydroxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid Chemical compound CC(C)(C)OC(=O)N[C@H](C(O)=O)CC1=CC=C(O)C=C1 CNBUSIJNWNXLQQ-NSHDSACASA-N 0.000 abstract 1
- PUUABEGDHGDROR-RYUDHWBXSA-N (2s)-4-methyl-2-[[(2s)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoyl]amino]pentanoic acid Chemical compound CC(C)C[C@@H](C(O)=O)NC(=O)[C@H](C(C)C)NC(=O)OC(C)(C)C PUUABEGDHGDROR-RYUDHWBXSA-N 0.000 abstract 1
- PBGVVLQMNSPMKN-LURJTMIESA-N 2-[[(2s)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]acetic acid Chemical compound CC(C)(C)OC(=O)N[C@@H](C)C(=O)NCC(O)=O PBGVVLQMNSPMKN-LURJTMIESA-N 0.000 abstract 1
- -1 Boc Chemical class 0.000 abstract 1
- 108010016626 Dipeptides Proteins 0.000 abstract 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 1
- CIVKXGPFXDIQBV-WDCWCFNPSA-N Leu-Gln-Thr Chemical compound CC(C)C[C@H](N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O CIVKXGPFXDIQBV-WDCWCFNPSA-N 0.000 abstract 1
- HMNSRTLZAJHSIK-YUMQZZPRSA-N Pro-Arg Chemical compound NC(=N)NCCC[C@@H](C(O)=O)NC(=O)[C@@H]1CCCN1 HMNSRTLZAJHSIK-YUMQZZPRSA-N 0.000 abstract 1
- CELJCNRXKZPTCX-XPUUQOCRSA-N Val-Gly-Ala Chemical compound CC(C)[C@H](N)C(=O)NCC(=O)N[C@@H](C)C(O)=O CELJCNRXKZPTCX-XPUUQOCRSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- JNYKZWBVTXFUBQ-LBPRGKRZSA-N benzyl 2-[[(2s)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]acetate Chemical compound CC(C)(C)OC(=O)N[C@@H](C)C(=O)NCC(=O)OCC1=CC=CC=C1 JNYKZWBVTXFUBQ-LBPRGKRZSA-N 0.000 abstract 1
- XWIVIUWAOYMFBI-INIZCTEOSA-N benzyl 2-[[(2s)-4-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoyl]amino]acetate Chemical compound CC(C)(C)OC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)OCC1=CC=CC=C1 XWIVIUWAOYMFBI-INIZCTEOSA-N 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/585—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50052064A JPS51128993A (en) | 1975-05-01 | 1975-05-01 | Process for preparing new polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1516947A true GB1516947A (en) | 1978-07-05 |
Family
ID=12904371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB17691/76A Expired GB1516947A (en) | 1975-05-01 | 1976-04-30 | Hentricontapeptides |
Country Status (15)
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2590902A1 (fr) * | 1985-12-04 | 1987-06-05 | Sandoz Sa | Nouveaux derives de la calcitonine, leur preparation et leur utilisation comme medicaments |
| US5122376A (en) * | 1989-05-12 | 1992-06-16 | Isf Societa Per Azioni | Calcitonin gene related peptide |
| US5183802A (en) * | 1987-11-13 | 1993-02-02 | Isf Societa Per Azioni | Pharmaceutical compositions for intranasal administration of calcitonin |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5359688A (en) * | 1976-11-11 | 1978-05-29 | Tanpakushitsu Kenkiyuu Shiyour | Production of novel polypeptide |
| JPS5850213B2 (ja) * | 1977-06-20 | 1983-11-09 | 株式会社第一ラジオアイソト−プ研究所 | カルチトニンの定量法 |
| US4514331A (en) * | 1983-06-29 | 1985-04-30 | University Patents, Inc. | Peptide hormones with calcitonin-like activity |
| US4663309A (en) * | 1983-06-29 | 1987-05-05 | University Patents, Inc. | Novel peptide hormones with calcitonin-like activity |
| US4528132A (en) * | 1984-01-13 | 1985-07-09 | Armour Pharmaceutical Company | [16-Alanine]calcitonin |
| US4605515A (en) * | 1984-10-24 | 1986-08-12 | Armour Pharmaceutical Company | Calcitonin-(1-23)-peptide amide |
| JPS61112099A (ja) * | 1984-11-06 | 1986-05-30 | Mitsubishi Petrochem Co Ltd | 新規ポリペプチド及びその製造法 |
| US4604237A (en) * | 1984-11-20 | 1986-08-05 | Armour Pharmaceutical Company | Des-21-threonine-calcitonin |
| US4604238A (en) * | 1984-12-10 | 1986-08-05 | Armour Pharmaceutical Company | Analogs of calcitonin |
| US4604236A (en) * | 1985-03-18 | 1986-08-05 | Orlowski Ronald C | Calcitonin analogs |
| US4622387A (en) * | 1985-06-19 | 1986-11-11 | Armour Pharmaceutical Co. | 8-methionine calcitonin |
| US4632978A (en) * | 1985-10-15 | 1986-12-30 | Armour Pharmaceutical Corp. | 6-serine, des-19-leucine calcitonin |
| US4639511A (en) * | 1985-11-12 | 1987-01-27 | Armour Pharmaceutical Company | Des-19-leucine-calcitonin analogs |
| US4658014A (en) * | 1985-12-20 | 1987-04-14 | Kempe Tomas G | Synthetic peptides with calcitonin-like activity |
| US5656723A (en) * | 1985-12-24 | 1997-08-12 | Milhaud; Gerard | Analogues of hypocalcemiant polypeptide compounds sparing the calcium of the organism, their preparation, their use as medicaments and the compositions containing them |
| FR2592049B1 (fr) * | 1985-12-24 | 1988-02-12 | Milhaud Gerard | Nouveaux analogues de composes polypeptidiques hypocalcemiants epargnant le calcium de l'organisme, leur preparation et les medicaments contenant ces principes actifs |
| JPH02262595A (ja) * | 1988-02-29 | 1990-10-25 | Otsuka Pharmaceut Co Ltd | ポリペプチド誘導体 |
| GB2218102B (en) * | 1988-04-08 | 1992-09-16 | Sandoz Ltd | Calcitonin peptide derivatives |
| JPH02174726A (ja) * | 1988-12-23 | 1990-07-06 | Toyo Jozo Co Ltd | エルカトニン水溶液組成物の安定化法 |
| US5204326A (en) * | 1989-03-16 | 1993-04-20 | Otsuka Pharmaceutical Co., Ltd. | Polypeptide derivatives and calcium metabolism improving agent |
| DK0423326T3 (da) * | 1989-04-21 | 1999-05-25 | Tsumura & Co | Hidtil ukendt fysiologisk aktivt peptid og calcium-metabolisme-regulerende middel, der omfatter peptidet som effektiv besta |
| WO1991007433A1 (fr) * | 1989-11-08 | 1991-05-30 | Daicel Chemical Industries, Ltd. | Peptide et procede de preparation d'un peptide cyclique |
| CS89491A3 (en) * | 1990-04-09 | 1992-01-15 | Chugai Pharmaceutical Co Ltd | Hybrid calcitonin |
| ES2055665B1 (es) * | 1993-02-03 | 1995-03-01 | Lipotec Sa | Procedimiento para la obtencion de carbocalcitonina. |
| US5721207A (en) * | 1995-04-18 | 1998-02-24 | Innapharma, Inc. | Method for treatment of pain |
| US5962270A (en) | 1996-02-06 | 1999-10-05 | Bionebraska, Inc. | Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs |
| US6083480A (en) | 1997-05-01 | 2000-07-04 | Diatide, Inc. | Calcitonin receptor binding reagents |
| AU2003272814A1 (en) | 2003-10-02 | 2005-05-19 | Ibrahim Al-Habdan | Peptide for promoting healing of fractures |
| KR101118364B1 (ko) | 2006-09-27 | 2012-06-01 | 아사히 가세이 파마 가부시키가이샤 | 뇌졸중 후의 반사성 교감 신경성 디스트로피 발증 예방제 |
| FR3152435B1 (fr) | 2023-09-04 | 2025-07-18 | Psa Automobiles Sa | Vehicule automobile comprenant des connexions conductrices de courant entre les couvercles et inserts de la batterie de traction, et procede sur la base d’un tel vehicule |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH523868A (de) * | 1969-10-22 | 1972-06-15 | Ciba Geigy Ag | Verfahren zur Herstellung neuer Dotriacontapeptidamide und ihrer Derivate |
| JPS4843918A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1971-10-08 | 1973-06-25 | ||
| JPS5716977B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1972-12-07 | 1982-04-08 |
-
1975
- 1975-05-01 JP JP50052064A patent/JPS51128993A/ja active Granted
-
1976
- 1976-04-14 DE DE2616399A patent/DE2616399C2/de not_active Expired
- 1976-04-14 FR FR7610955A patent/FR2309235A1/fr active Granted
- 1976-04-22 CA CA250,777A patent/CA1065856A/en not_active Expired
- 1976-04-23 NZ NZ180675A patent/NZ180675A/xx unknown
- 1976-04-26 SE SE7604761A patent/SE437836B/xx not_active IP Right Cessation
- 1976-04-28 AT AT311476A patent/AT360670B/de not_active IP Right Cessation
- 1976-04-29 HU HU76TO1029A patent/HU176623B/hu unknown
- 1976-04-29 NL NL7604605.A patent/NL164551C/xx not_active IP Right Cessation
- 1976-04-30 DK DK193876A patent/DK149597C/da active
- 1976-04-30 BE BE166656A patent/BE841376A/xx not_active IP Right Cessation
- 1976-04-30 GB GB17691/76A patent/GB1516947A/en not_active Expired
- 1976-04-30 CH CH549076A patent/CH624660A5/de not_active IP Right Cessation
- 1976-05-03 AU AU13565/76A patent/AU508162B2/en not_active Expired
- 1976-05-03 US US05/682,752 patent/US4086221A/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2590902A1 (fr) * | 1985-12-04 | 1987-06-05 | Sandoz Sa | Nouveaux derives de la calcitonine, leur preparation et leur utilisation comme medicaments |
| GB2184729A (en) * | 1985-12-04 | 1987-07-01 | Sandoz Ltd | Calcitonin derivatives |
| GB2184729B (en) * | 1985-12-04 | 1990-07-25 | Sandoz Ltd | "new calcitonin derivatives" |
| US5183802A (en) * | 1987-11-13 | 1993-02-02 | Isf Societa Per Azioni | Pharmaceutical compositions for intranasal administration of calcitonin |
| US5122376A (en) * | 1989-05-12 | 1992-06-16 | Isf Societa Per Azioni | Calcitonin gene related peptide |
Also Published As
| Publication number | Publication date |
|---|---|
| AU1356576A (en) | 1977-11-10 |
| US4086221A (en) | 1978-04-25 |
| NL164551B (nl) | 1980-08-15 |
| DE2616399C2 (de) | 1986-03-27 |
| ATA311476A (de) | 1980-06-15 |
| DK193876A (da) | 1976-11-02 |
| SE437836B (sv) | 1985-03-18 |
| SE7604761L (sv) | 1976-11-02 |
| JPS51128993A (en) | 1976-11-10 |
| DK149597C (da) | 1987-01-05 |
| NL7604605A (nl) | 1976-11-03 |
| JPS5341677B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-11-06 |
| CH624660A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1981-08-14 |
| FR2309235B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-11-17 |
| NZ180675A (en) | 1978-09-20 |
| DK149597B (da) | 1986-08-04 |
| DE2616399A1 (de) | 1976-11-11 |
| BE841376A (fr) | 1976-11-03 |
| HU176623B (en) | 1981-03-28 |
| CA1065856A (en) | 1979-11-06 |
| NL164551C (nl) | 1981-01-15 |
| AT360670B (de) | 1981-01-26 |
| FR2309235A1 (fr) | 1976-11-26 |
| AU508162B2 (en) | 1980-03-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| 704A | Declaration that licence is not available as of right for an excepted use (par. 4a/1977) | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19960429 |