GB1516458A - Microorganisms and method of preparing and using same - Google Patents

Microorganisms and method of preparing and using same

Info

Publication number
GB1516458A
GB1516458A GB4066476A GB4066476A GB1516458A GB 1516458 A GB1516458 A GB 1516458A GB 4066476 A GB4066476 A GB 4066476A GB 4066476 A GB4066476 A GB 4066476A GB 1516458 A GB1516458 A GB 1516458A
Authority
GB
United Kingdom
Prior art keywords
microorganism
recombinant dna
incorporated
genetic information
foreign genetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4066476A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Corp
Original Assignee
Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp filed Critical Research Corp
Publication of GB1516458A publication Critical patent/GB1516458A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02WCLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
    • Y02W10/00Technologies for wastewater treatment
    • Y02W10/30Wastewater or sewage treatment systems using renewable energies
    • Y02W10/37Wastewater or sewage treatment systems using renewable energies using solar energy
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
GB4066476A 1976-09-27 1976-09-30 Microorganisms and method of preparing and using same Expired GB1516458A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/727,365 US4190495A (en) 1976-09-27 1976-09-27 Modified microorganisms and method of preparing and using same

Publications (1)

Publication Number Publication Date
GB1516458A true GB1516458A (en) 1978-07-05

Family

ID=24922359

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4066476A Expired GB1516458A (en) 1976-09-27 1976-09-30 Microorganisms and method of preparing and using same

Country Status (4)

Country Link
US (1) US4190495A (https=)
JP (1) JPS5341477A (https=)
DE (1) DE2644432A1 (https=)
GB (1) GB1516458A (https=)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0029497A1 (en) * 1979-10-15 1981-06-03 The University Of Rochester Asporogenous mutant of bacillus subtilis and process for the use thereof as host component of a HV1 system
US4337314A (en) 1979-05-23 1982-06-29 Research Corporation Genetically attenuated bacterial vaccines with multiple mutations of the same phenotype
US4338397A (en) 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
US4411994A (en) 1978-06-08 1983-10-25 The President And Fellows Of Harvard College Protein synthesis
US4565785A (en) * 1978-06-08 1986-01-21 The President And Fellows Of Harvard College Recombinant DNA molecule
FR2602792A1 (fr) * 1986-08-05 1988-02-19 Transgene Sa Procede de stabilisation d'un plasmide contenu dans une souche bacterienne et souche obtenue
US6268122B1 (en) 1978-12-22 2001-07-31 Biogen, Inc. Recombinant DNA molecules and their method of production
US7588755B1 (en) 1980-04-03 2009-09-15 Biogen Idec Ma Inc. DNA sequences, recombinant DNA molecules and processes for producing human fibroblast interferon-like polypeptides
US7871604B1 (en) * 1995-06-07 2011-01-18 Washington University Recombinant bacterial vaccine system with environmentally limited viability
GB2473523A (en) * 2009-09-10 2011-03-16 Solus Scient Solutions Ltd Nalidixic acid and lithium in a base medium for the culture of Listeria

Families Citing this family (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583013A (en) * 1977-11-08 1996-12-10 Genentech, Inc. Method and means for microbial polypeptide expression
US5221619A (en) * 1977-11-08 1993-06-22 Genentech, Inc. Method and means for microbial polypeptide expression
US4704362A (en) * 1977-11-08 1987-11-03 Genentech, Inc. Recombinant cloning vehicle microbial polypeptide expression
FR2422685A1 (fr) * 1978-04-14 1979-11-09 Pasteur Institut Vecteurs, derives du bacteriophage lambda, permettant l'insertion et l'expression d'un gene, procaryote ou eucaryote, sous le controle du promoteur et de l'operateur de l'operon lactose de la bacterie escherichia coli
US4322497A (en) * 1978-06-02 1982-03-30 Eli Lilly And Company Process for transducing Escherichia coli K12 χ1776
IE48385B1 (en) * 1978-08-11 1984-12-26 Univ California Synthesis of a eucaryotic protein by a microorganism
JPS55156591A (en) * 1979-05-23 1980-12-05 Ajinomoto Co Inc Method for stabilizing property of bacteria containing plasmid
US4342832A (en) * 1979-07-05 1982-08-03 Genentech, Inc. Method of constructing a replicable cloning vehicle having quasi-synthetic genes
DE2931999A1 (de) * 1979-08-03 1981-02-26 Schering Ag Herstellung und anwendung von neukombinierten plasmiden mit genen fuer alkalische phosphatasen
US4886754A (en) * 1980-01-07 1989-12-12 The University Of Rochester Recombinant bateriophage for heterologous cloning of bacillus microorganisms and method for its production
US6835557B1 (en) 1980-01-08 2004-12-28 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
US4370417A (en) * 1980-04-03 1983-01-25 Abbott Laboratories Recombinant deoxyribonucleic acid which codes for plasminogen activator
US4558010A (en) * 1980-04-03 1985-12-10 Abbott Laboratories Recombinant deoxyribonucleic acid which codes for plasminogen activator and method of making plasminogen activator protein therefrom
US5643771A (en) * 1980-05-19 1997-07-01 The Board Of Trustees Of The Leland Stanford Junior University Non-reverting live bacterial vaccines
US4357298A (en) * 1980-10-10 1982-11-02 General Electric Company Nuclear fuel assembly space arrangement
US4888170A (en) * 1981-10-22 1989-12-19 Research Corporation Vaccines obtained from antigenic gene products of recombinant genes
JPS60137291A (ja) * 1983-12-26 1985-07-20 Takeda Chem Ind Ltd 発現ベクター
US4959463A (en) 1985-10-15 1990-09-25 Genentech, Inc. Intermediates
JPS63264061A (ja) * 1987-04-23 1988-10-31 吉田精工株式会社 歯科用治療椅子の制御装置
US5387744A (en) * 1987-06-04 1995-02-07 Washington University Avirulent microbes and uses therefor: Salmonella typhi
US5855880A (en) * 1987-06-04 1999-01-05 Washington University Avirulent microbes and uses therefor
US5294441A (en) * 1987-06-04 1994-03-15 Washington University Avirulent microbes and uses therefor: salmonella typhi
US5030574A (en) * 1987-06-19 1991-07-09 Vary Patricia S Plasmidless Lac strain of bacilus megaterium QM B1551
US5037757A (en) * 1987-07-20 1991-08-06 Board Of Regents For Northern Illinois University Plasmidless strain of Bacillus megaterium QM B1551
DE3853683T2 (de) * 1987-10-07 1995-08-31 Univ Washington Verfahren zur erhaltung eines erwünschten rekombinanten gens in einer genetischen zellpopulation.
US5082767A (en) * 1989-02-27 1992-01-21 Hatfield G Wesley Codon pair utilization
EP0681025B1 (en) * 1990-01-08 2001-05-09 Stratagene Novel cloning host organisms
GB9206318D0 (en) * 1992-03-24 1992-05-06 Cambridge Antibody Tech Binding substances
ATE177787T1 (de) * 1990-11-21 1999-04-15 Univ Washington Rekombinante avirulente salmonella antifruchtbarkeitsimpfstoffe
US6225447B1 (en) 1991-05-15 2001-05-01 Cambridge Antibody Technology Ltd. Methods for producing members of specific binding pairs
DE69230142T2 (de) 1991-05-15 2000-03-09 Cambridge Antibody Technology Ltd. Verfahren zur herstellung von spezifischen bindungspaargliedern
US6492160B1 (en) 1991-05-15 2002-12-10 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
US5858657A (en) * 1992-05-15 1999-01-12 Medical Research Council Methods for producing members of specific binding pairs
US5962255A (en) * 1992-03-24 1999-10-05 Cambridge Antibody Technology Limited Methods for producing recombinant vectors
US5733743A (en) * 1992-03-24 1998-03-31 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
CA2143299A1 (en) * 1992-09-04 1994-03-17 University Of Saskatchewan Novel bacterial vaccines using vaccine strains of pathogenic bacteria
FR2738842B1 (fr) * 1995-09-15 1997-10-31 Rhone Poulenc Rorer Sa Molecule d'adn circulaire a origine de replication conditionnelle, leur procede de preparation et leur utilisation en therapie genique
US7279313B2 (en) * 1995-09-15 2007-10-09 Centelion Circular DNA molecule having a conditional origin of replication, process for their preparation and their use in gene therapy
US5922583A (en) * 1995-10-17 1999-07-13 Biostar Inc. Methods for production of recombinant plasmids
US5869301A (en) * 1995-11-02 1999-02-09 Lockhead Martin Energy Research Corporation Method for the production of dicarboxylic acids
US5770435A (en) * 1995-11-02 1998-06-23 University Of Chicago Mutant E. coli strain with increased succinic acid production
US5645831A (en) * 1996-03-22 1997-07-08 Biodiscovery New Zealand Ltd. Bacillus thuringiensis strain and metabolite which are active against corn rootworm
US6221364B1 (en) 1996-11-12 2001-04-24 Albert Einstein College Of Medicine Of Yeshiva University Recombinant mycobacteria auxotrophic for diaminopimelate
US5733544A (en) * 1996-11-18 1998-03-31 University Of Saskatchewan Nematicidal bacillus strain and metabolite and methods of use thereof
US6537558B2 (en) 1997-03-31 2003-03-25 Megan Health, Inc. Methods of producing and using virulence attenuated poxR mutant bacteria
US6780405B1 (en) 2000-04-28 2004-08-24 Avant Immunotherapeutics, Inc. Regulated antigen delivery system (RADS)
US6872547B1 (en) 2000-10-11 2005-03-29 Washington University Functional balanced-lethal host-vector systems
US20040137003A1 (en) * 2001-04-30 2004-07-15 Curtiss Iii Roy Regulated antigen delivery system (rads)
US7780961B2 (en) * 2001-05-03 2010-08-24 Actogenix N.V. Self-containing Lactococcus strain
US20030194798A1 (en) * 2001-05-24 2003-10-16 Surber Mark W. Minicell compositions and methods
US7396822B2 (en) 2001-05-24 2008-07-08 Vaxiion Therapeutics, Inc. Immunogenic minicells and methods of use
US6852485B1 (en) 2002-01-22 2005-02-08 California State University Fullerton Foundation Method for identifying a compound for the treatment of microorganism infections by inhibiting energy storage and utilization in pathogens
US20030224369A1 (en) * 2002-02-25 2003-12-04 Surber Mark W. Reverse screening and target identification with minicells
US20030224444A1 (en) * 2002-02-25 2003-12-04 Sabbadini Roger A. Antibodies to native conformations of membrane proteins
US20030207833A1 (en) * 2002-02-25 2003-11-06 Neil Berkley Pharmaceutical compositions with minicells
AU2002318168B2 (en) 2002-02-25 2007-12-13 Vaxiion Therapeutics, Llc Minicell compositions and methods
JP2005529622A (ja) * 2002-06-19 2005-10-06 ヴェーイーベー・ヴェーゼットウェー 腸吸収を促進するための方法および手段
EP1537214B1 (en) * 2002-09-01 2006-03-01 Washington University Regulated bacterial lysis for gene vaccine vector delivery and antigen release
EP1620569B1 (en) * 2003-04-26 2009-12-09 Merck & Co., Inc. A forward mutation assay based on 5-fluorouracil resistance
WO2006055024A2 (en) * 2004-04-05 2006-05-26 Vaxiion Therapeutics, Inc. Minicells as vaccines
EP1616959A1 (en) * 2004-07-07 2006-01-18 Icon Genetics AG Biological safe transient protein expression in plants
AU2006284922B2 (en) 2005-08-30 2012-01-19 University Of Miami Immunomodulating tumor necrosis factor receptor 25 (TNFR25) agonists, antagonists and immunotoxins
CN101300356A (zh) * 2005-09-09 2008-11-05 基因组股份公司 用于琥珀酸盐之生长关联性生产的方法和生物
ES2405552T3 (es) 2005-11-29 2013-05-31 Actogenix N.V. Inducción de tolerancia mucosa a antiantígenos de células beta de islotes pancreáticos
US8673601B2 (en) * 2007-01-22 2014-03-18 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
WO2008090223A2 (en) 2007-01-25 2008-07-31 Actogenix N.V. Treatment of immune disease by mucosal delivery of antigens using genetically modified lactobacillus
AU2008254291B2 (en) 2007-05-01 2015-09-24 Synthetic Genomics, Inc. Methods of genome installation in a recipient host cell
EP2152883A4 (en) * 2007-05-10 2010-10-27 Univ Arizona RECOMBINANT BACTERIA WITH VECTORS FOR THE EXPRESSION OF NUCLEIC ACID SEQUENCES-CODING ANTIGENES
WO2009025888A2 (en) 2007-05-10 2009-02-26 The Arizona Board Of Regents For And On Behalf Of Arizona State University Regulated synthesis of antigen and/or regulated attentuation to enhance vaccine immunogenics and/or safety
US8026386B2 (en) * 2007-08-10 2011-09-27 Genomatica, Inc. Methods for the synthesis of olefins and derivatives
US8465755B2 (en) * 2007-10-05 2013-06-18 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium capable of eliciting an immune response against enteric pathogens
CA2712779C (en) * 2008-01-22 2021-03-16 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
ES2656790T3 (es) * 2008-03-27 2018-02-28 Genomatica, Inc. Microorganismos para la producción de ácido adípico y otros compuestos
WO2009135074A2 (en) * 2008-05-01 2009-11-05 Genomatica, Inc. Microorganisms for the production of methacrylic acid
BRPI0913901A2 (pt) * 2008-06-17 2016-12-13 Genomatica Inc micro-organismos e métodos para a biossíntese de fumarato, malato e acrilato
US20100021978A1 (en) * 2008-07-23 2010-01-28 Genomatica, Inc. Methods and organisms for production of 3-hydroxypropionic acid
US9446227B2 (en) 2008-09-12 2016-09-20 Sonescence, Inc. Ultrasonic dispersion of compositions in tissue
US20100069827A1 (en) 2008-09-12 2010-03-18 Barry Neil Silberg Pre-Surgical Prophylactic Administration of Antibiotics and Therapeutic Agents
WO2010045620A1 (en) 2008-10-17 2010-04-22 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium capable of eliciting an immune response against streptococcus pneumoniae
WO2010057022A1 (en) * 2008-11-14 2010-05-20 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
EP2373781A4 (en) * 2008-12-16 2012-10-10 Genomatica Inc MICRO-ORGANISMS AND METHODS OF CONVERTING SYNGAS AND OTHER CARBON RESOURCES IN USEFUL PRODUCTS
US9163219B2 (en) * 2009-04-14 2015-10-20 Arizona Board Of Regents On Behalf Of Arizona State University Single expression vector for generation of a virus with a segmented genome
MY176050A (en) * 2009-04-30 2020-07-22 Genomatica Inc Organisms for the production of 1,3-butanediol
BRPI1013505A2 (pt) 2009-04-30 2018-02-14 Genomatica Inc organismos para a produção de isopropanol, n-butanol, e isobutanol
EP2427544B1 (en) 2009-05-07 2019-07-17 Genomatica, Inc. Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid
JP2012526561A (ja) * 2009-05-15 2012-11-01 ゲノマチカ, インク. シクロヘキサノンの産生のための生物
GB2483595B (en) 2009-05-22 2017-03-29 The Arizona Board Of Regents For And On Behalf Of Arizona State Univ Recombinant bacterium and methods of antigen and nucleic acid delivery
US9045742B2 (en) * 2009-05-29 2015-06-02 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant Edwardsiella bacterium
EP2440669A4 (en) * 2009-06-10 2013-08-28 Genomatica Inc MICROOGANISMS AND PROCEDURES FOR THE CARBON EFFECTIVE BIOSYNTHESIS MEK AND 2-BUTANOL
SG10201502330TA (en) 2009-08-03 2015-05-28 Univ Miami Method for in vivo expansion of t regulatory cells
EP3190174A1 (en) 2009-08-05 2017-07-12 Genomatica, Inc. Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
US8715971B2 (en) 2009-09-09 2014-05-06 Genomatica, Inc. Microorganisms and methods for the co-production of isopropanol and 1,4-butanediol
KR20120083908A (ko) 2009-10-13 2012-07-26 게노마티카 인코포레이티드 1,4-부탄다이올, 4-하이드록시부탄알, 4-하이드록시부티릴-coa, 푸트레신 및 관련 화합물의 제조를 위한 미생물 및 관련 방법
KR20180014240A (ko) 2009-10-23 2018-02-07 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
KR20120120493A (ko) * 2009-12-10 2012-11-01 게노마티카 인코포레이티드 합성 가스 또는 기타 가스상 탄소원 및 메탄올을 1,3-부탄디올로 변환하는 방법 및 변환용 유기체
US9062297B2 (en) 2010-01-13 2015-06-23 The Arizona Board Of Regents For And On Behalf Of Arizona State University Yersinia pestis vaccine
WO2011091291A1 (en) 2010-01-22 2011-07-28 The Arizona Board Of Regents For And On Behalf Of Arizona State University BACTERIUM COMPRISING A REGULATED rfaH NUCLEIC ACID
JP2013517796A (ja) * 2010-01-29 2013-05-20 ジェノマティカ・インコーポレイテッド p−トルイル酸およびテレフタル酸を生合成するための方法および微生物
US8445244B2 (en) * 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
CA2797409C (en) 2010-05-05 2019-12-24 Genomatica, Inc. Microorganisms and methods for the biosynthesis of butadiene
WO2011150421A2 (en) 2010-05-28 2011-12-01 The Arizona Board Of Regents For And On Behalf Of Arizona State University Recombinant bacterium to decrease tumor growth
US9255283B2 (en) 2010-07-02 2016-02-09 The Arizona Board Of Regents For And On Behalf Of Arizona State University Compositions and methods for bacterial lysis and neutral lipid production
PH12013500158A1 (en) 2010-07-26 2013-03-11 Genomatica Inc Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
CA2827443C (en) 2011-02-15 2021-07-06 Vaxiion Therapeutics, Inc. Therapeutic compositions and methods for antibody and fc-containing targeting molecule-based targeted delivery of bioactive molecules by bacterial minicells
US9303264B2 (en) 2012-05-18 2016-04-05 The Arizona Board Of Regents For And On Behalf Of Arizona State University Photosynthetic microorganisms expressing thermostable lipase
US20140193410A1 (en) 2013-01-09 2014-07-10 University Of Miami Compositions and Methods for the Regulation of T Regulatory Cells Using TL1A-Ig Fusion Protein
US9580718B2 (en) 2013-06-17 2017-02-28 Arizona Board Of Regents On Behalf Of Arizona State University Attenuated live bacteria with increased acid resistance and methods of use thereof
US9956388B2 (en) 2014-06-04 2018-05-01 Sonescence, Inc. Systems and methods for therapeutic agent delivery
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411994A (en) 1978-06-08 1983-10-25 The President And Fellows Of Harvard College Protein synthesis
US4565785A (en) * 1978-06-08 1986-01-21 The President And Fellows Of Harvard College Recombinant DNA molecule
US6268122B1 (en) 1978-12-22 2001-07-31 Biogen, Inc. Recombinant DNA molecules and their method of production
US6270955B1 (en) 1978-12-22 2001-08-07 Biogen, Inc. Pharmaceutical compositions and methods for producing antibodies to hepatitis b virus and kits and methods for detecting antibodies to hepatitis b virus
US6297355B1 (en) 1978-12-22 2001-10-02 Biogen, Inc. Polypeptides displaying HBV antigenicity or hbv antigen specificity
US4337314A (en) 1979-05-23 1982-06-29 Research Corporation Genetically attenuated bacterial vaccines with multiple mutations of the same phenotype
EP0029497A1 (en) * 1979-10-15 1981-06-03 The University Of Rochester Asporogenous mutant of bacillus subtilis and process for the use thereof as host component of a HV1 system
US7588755B1 (en) 1980-04-03 2009-09-15 Biogen Idec Ma Inc. DNA sequences, recombinant DNA molecules and processes for producing human fibroblast interferon-like polypeptides
US4338397A (en) 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
FR2602792A1 (fr) * 1986-08-05 1988-02-19 Transgene Sa Procede de stabilisation d'un plasmide contenu dans une souche bacterienne et souche obtenue
US7871604B1 (en) * 1995-06-07 2011-01-18 Washington University Recombinant bacterial vaccine system with environmentally limited viability
GB2473523A (en) * 2009-09-10 2011-03-16 Solus Scient Solutions Ltd Nalidixic acid and lithium in a base medium for the culture of Listeria

Also Published As

Publication number Publication date
DE2644432A1 (de) 1978-03-30
DE2644432C2 (https=) 1988-12-29
US4190495A (en) 1980-02-26
JPS6246152B2 (https=) 1987-09-30
JPS5341477A (en) 1978-04-14

Similar Documents

Publication Publication Date Title
GB1516458A (en) Microorganisms and method of preparing and using same
Götz et al. Improvements of protoplast transformation in Staphylococcus carnosus
RU94035744A (ru) Днк, микроорганизм, способ получения z-треонина
Allcock et al. Autolytic activity and an autolysis-deficient mutant of Clostridium acetobutylicum
BOWRING et al. Mutagenesis of Clostridium acetobutylicum
US5061625A (en) Process for the preparation of a microorganism which forms α-galactosidase but not invertase, a microorganism thus obtained, and its use
Alačević Interspecific recombination in Streptomyces
Chatterjee et al. Induction of nonpigmented variants of Erwinia herbicola by incubation at supraoptimal temperatures
Boronin et al. Plasmids specifying∈-caprolactam degradation in Pseudomonas strains
GB1352545A (en) Fermentation process
US3063914A (en) Process for the biological preparation of streptokinase
EP0281523B1 (en) Pseudomonas
JP3013008B2 (ja) 無胞子性菌株バシラス・サチリス sms275
António Couto et al. Enhancement of apparent resistance to ethanol in Lactobacillus hilgardii
Halfmann et al. Different sensitivity of autolytic deficient Escherichia coli mutants to the mode of induction
DE3689181T2 (de) Thermostabile Tryptophanase, Verfahren zu deren Herstellung und thermostabile Tryptophanase erzeugender Mikroorganismus.
RU2003689C1 (ru) Рекомбинантна плазмидна ДНК рВА1418, кодирующа альфа-амилазу BACILLUS AMYLOLIQUEFACIENS и штамм-бактерий BACILLUS AMYLOLIQUEFACIENS - продуцент альфа-амилазы BACILLUS AMYLOLIQUEFACIENS
Mead A medium for the isolation of Streptococcus faecalis, sensu strictu
Cheng et al. Predominant growth of α-amylase regulation mutant in continuous culture of Bacillus caldolyticus
RU2103363C1 (ru) Рекомбинантная плазмидная днк рвтn ii, определяющая синтез кристаллического инсектицидного дельта-эндотоксина cry iiia-типа, способ ее конструирования и штамм бактерий pseudomonas putida, содержащий рекомбинантную плазмиду днк рвтn ii-продуцент кристаллического инсектицидного дельта-эндотоксина cry iiia-типа, активного против насекомых отряда coleoptera
Imanaka Host—vector systems in thermophilic Bacilli and their applications
Moore cdc9 ligase-defective mutants of Saccharomyces cerevisiae exhibit lowered resistance to lethal effects of bleomycin
US5037757A (en) Plasmidless strain of Bacillus megaterium QM B1551
US5030574A (en) Plasmidless Lac strain of bacilus megaterium QM B1551
Pavlasová et al. Selection aid properties of hyperproducing D-serine deaminase mutants of Escherichia coli

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee