GB1511736A - Amidino-hydrazone derivatives of benzocycloalkanones - Google Patents
Amidino-hydrazone derivatives of benzocycloalkanonesInfo
- Publication number
- GB1511736A GB1511736A GB21786/75A GB2178675A GB1511736A GB 1511736 A GB1511736 A GB 1511736A GB 21786/75 A GB21786/75 A GB 21786/75A GB 2178675 A GB2178675 A GB 2178675A GB 1511736 A GB1511736 A GB 1511736A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- reacting
- acid addition
- prepared
- addition salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 239000002253 acid Substances 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000005530 alkylenedioxy group Chemical group 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- WFJFGMLKAISFOZ-UHFFFAOYSA-N 1-amino-3-iminourea Chemical compound NN=C(O)N=N WFJFGMLKAISFOZ-UHFFFAOYSA-N 0.000 abstract 1
- LWHHDDZFBOKZDJ-UHFFFAOYSA-N 3,5-dimethylbicyclo[4.2.0]octa-1,3,5-trien-7-one Chemical compound CC1=CC(C)=CC2=C1C(=O)C2 LWHHDDZFBOKZDJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- FKLJPTJMIBLJAV-UHFFFAOYSA-N Compound IV Chemical compound O1N=C(C)C=C1CCCCCCCOC1=CC=C(C=2OCCN=2)C=C1 FKLJPTJMIBLJAV-UHFFFAOYSA-N 0.000 abstract 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- ZRALSGWEFCBTJO-UHFFFAOYSA-N anhydrous guanidine Natural products NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 125000005605 benzo group Chemical group 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- RDHPKYGYEGBMSE-UHFFFAOYSA-N bromoethane Chemical compound CCBr RDHPKYGYEGBMSE-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- BRWIZMBXBAOCCF-UHFFFAOYSA-N hydrazinecarbothioamide Chemical compound NNC(N)=S BRWIZMBXBAOCCF-UHFFFAOYSA-N 0.000 abstract 1
- QNXSIUBBGPHDDE-UHFFFAOYSA-N indan-1-one Chemical compound C1=CC=C2C(=O)CCC2=C1 QNXSIUBBGPHDDE-UHFFFAOYSA-N 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- VFIZBHJTOHUOEK-UHFFFAOYSA-N s-ethylisothiourea Chemical compound CCSC(N)=N VFIZBHJTOHUOEK-UHFFFAOYSA-N 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- SRVJKTDHMYAMHA-WUXMJOGZSA-N thioacetazone Chemical compound CC(=O)NC1=CC=C(\C=N\NC(N)=S)C=C1 SRVJKTDHMYAMHA-WUXMJOGZSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
- C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/52—Nitrogen atoms not forming part of a nitro radical with hetero atoms directly attached to said nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7407469A NL7407469A (nl) | 1974-06-01 | 1974-06-01 | Nieuwe amidinohydrazonverbindingen. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1511736A true GB1511736A (en) | 1978-05-24 |
Family
ID=19821484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB21786/75A Expired GB1511736A (en) | 1974-06-01 | 1975-05-21 | Amidino-hydrazone derivatives of benzocycloalkanones |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4076726A (en, 2012) |
| JP (1) | JPS514155A (en, 2012) |
| BE (1) | BE829748A (en, 2012) |
| CA (1) | CA1064503A (en, 2012) |
| DE (1) | DE2524114A1 (en, 2012) |
| DK (1) | DK234475A (en, 2012) |
| ES (1) | ES438102A1 (en, 2012) |
| FI (1) | FI751583A7 (en, 2012) |
| FR (1) | FR2272653B1 (en, 2012) |
| GB (1) | GB1511736A (en, 2012) |
| IE (1) | IE41070B1 (en, 2012) |
| NL (1) | NL7407469A (en, 2012) |
| SE (1) | SE7506196L (en, 2012) |
| ZA (1) | ZA753299B (en, 2012) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3821873A (en) * | 1972-11-14 | 1974-07-02 | Jones & Co Inc R A | Method and apparatus for forming and filling pouches |
| DE3416695A1 (de) * | 1984-05-05 | 1985-11-07 | Bayer Ag, 5090 Leverkusen | Amidinohydrazone von tetralin-, chromon-, thiochromon- und tretrahydrochinolin-derivaten, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
| GB8508588D0 (en) * | 1985-04-02 | 1985-05-09 | Akzo Nv | Indene & napthalene derivatives |
| US5238941A (en) * | 1988-03-25 | 1993-08-24 | Ciba-Geigy Corporation | Arylhydrazones and pharmaceutical compositions thereof |
| US5395855A (en) * | 1990-05-07 | 1995-03-07 | Ciba-Geigy Corporation | Hydrazones |
| AU645799B2 (en) * | 1990-05-07 | 1994-01-27 | Novartis Ag | Hydrazones |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE942627C (de) * | 1952-12-25 | 1956-05-03 | Bayer Ag | Verfahren zur Herstellung von Bishydrazonen |
| US2865961A (en) * | 1955-03-04 | 1958-12-23 | Schenley Ind Inc | N, n' diguanido diimides of quinone-diolefin adducts |
| DE1211176B (de) * | 1964-04-02 | 1966-02-24 | Bayer Ag | Verfahren zur Herstellung von Amidinohydrazonen polycyclischer nichtaromatischer Verbindungen |
| FI48082C (fi) * | 1966-08-05 | 1974-06-10 | Boehringer Sohn Ingelheim | Menetelmä uusien verenpainetta alentavien 2-aryylihydratsino-imidatsol iinien-(2) valmistamiseksi |
| CH495995A (de) * | 1966-09-23 | 1970-09-15 | Ciba Geigy | Verfahren zur Herstellung neuer Hydrazinverbindungen |
| DE1670184A1 (de) * | 1967-01-20 | 1971-01-21 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung heterocyclisch substituierter Hydrazino-imidazoline-(2) |
| NL7011683A (en, 2012) * | 1970-08-07 | 1972-02-09 |
-
1974
- 1974-06-01 NL NL7407469A patent/NL7407469A/xx not_active Application Discontinuation
-
1975
- 1975-05-20 IE IE1130/75A patent/IE41070B1/xx unknown
- 1975-05-21 ZA ZA00753299A patent/ZA753299B/xx unknown
- 1975-05-21 GB GB21786/75A patent/GB1511736A/en not_active Expired
- 1975-05-21 US US05/579,633 patent/US4076726A/en not_active Expired - Lifetime
- 1975-05-27 DK DK234475A patent/DK234475A/da unknown
- 1975-05-29 FI FI751583A patent/FI751583A7/fi not_active Application Discontinuation
- 1975-05-29 JP JP50065207A patent/JPS514155A/ja active Pending
- 1975-05-30 CA CA228,174A patent/CA1064503A/en not_active Expired
- 1975-05-30 FR FR7516945A patent/FR2272653B1/fr not_active Expired
- 1975-05-30 BE BE156923A patent/BE829748A/xx unknown
- 1975-05-30 DE DE19752524114 patent/DE2524114A1/de active Pending
- 1975-05-30 SE SE7506196A patent/SE7506196L/xx unknown
- 1975-05-31 ES ES438102A patent/ES438102A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS514155A (en, 2012) | 1976-01-14 |
| IE41070L (en) | 1975-12-01 |
| BE829748A (fr) | 1975-12-01 |
| US4076726A (en) | 1978-02-28 |
| FR2272653A1 (en, 2012) | 1975-12-26 |
| FI751583A7 (en, 2012) | 1975-12-02 |
| IE41070B1 (en) | 1979-10-10 |
| CA1064503A (en) | 1979-10-16 |
| DE2524114A1 (de) | 1975-12-18 |
| ZA753299B (en) | 1976-04-28 |
| DK234475A (da) | 1975-12-02 |
| NL7407469A (nl) | 1975-12-03 |
| ES438102A1 (es) | 1977-06-16 |
| AU8140575A (en) | 1976-11-25 |
| FR2272653B1 (en, 2012) | 1978-11-10 |
| SE7506196L (sv) | 1975-12-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |