GB1507340A - Hydroxypolyhaloisopropyl substituted ureido-compounds - Google Patents
Hydroxypolyhaloisopropyl substituted ureido-compoundsInfo
- Publication number
- GB1507340A GB1507340A GB48640/75A GB4864075A GB1507340A GB 1507340 A GB1507340 A GB 1507340A GB 48640/75 A GB48640/75 A GB 48640/75A GB 4864075 A GB4864075 A GB 4864075A GB 1507340 A GB1507340 A GB 1507340A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- hydroxypolyhaloisopropyl
- substituted ureido
- image
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- CIDMUJMGDBSMQW-UHFFFAOYSA-N n-phenyl-4,5-dihydro-1,3-oxazol-2-amine Chemical class O1CCN=C1NC1=CC=CC=C1 CIDMUJMGDBSMQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/42—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
- C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/28—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52860374A | 1974-12-02 | 1974-12-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1507340A true GB1507340A (en) | 1978-04-12 |
Family
ID=24106378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB48640/75A Expired GB1507340A (en) | 1974-12-02 | 1975-11-26 | Hydroxypolyhaloisopropyl substituted ureido-compounds |
Country Status (26)
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000054759A3 (en) * | 1999-03-15 | 2001-02-15 | Tularik Inc | Lxr modulators |
| WO2003089404A1 (en) * | 2002-04-19 | 2003-10-30 | Abbott Laboratories | Naphthalene amides as potassium channel openers |
| US7071358B2 (en) | 2002-01-30 | 2006-07-04 | Amgen Inc. | Arylsulfonamidobenzylic compounds |
| US7112606B2 (en) | 2002-01-30 | 2006-09-26 | Amgen Inc. | Heterocyclic arylsulfonamidobenzylic compounds |
| CN107108485A (zh) * | 2014-10-24 | 2017-08-29 | 小野药品工业株式会社 | Kcnq2～5通道活化剂 |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52111541A (en) * | 1976-02-19 | 1977-09-19 | Scherico Ltd | Substituted ureido compound and medical composition containing it as active ingredient |
| US4107303A (en) | 1976-06-24 | 1978-08-15 | E. I. Du Pont De Nemours And Company | Antihypertensive hexafluorohydroxyisopropyl benzazepines and benzazocines |
| DE2839462A1 (de) * | 1978-09-11 | 1980-03-27 | Basf Ag | Aroylharnstoffe |
| CN1972897A (zh) * | 2004-06-28 | 2007-05-30 | 霍夫曼-拉罗奇有限公司 | 新型六氟异丙醇衍生物 |
| JP6197971B1 (ja) * | 2016-04-22 | 2017-09-20 | 小野薬品工業株式会社 | Ｋｃｎｑ２〜５チャネル関連疾患の予防および／または治療剤 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3453284A (en) * | 1966-01-19 | 1969-07-01 | Du Pont | Certain 2-(substituted-anilino)-2-oxazolines |
| DE1670752A1 (de) * | 1966-09-27 | 1970-12-23 | Bayer Ag | Verfahren zur Herstellung von 2-Phenylamino-oxazolinen |
| DE1670751A1 (de) * | 1966-09-27 | 1970-12-23 | Bayer Ag | Verfahren zur Herstellung von 2-Phenylamino-2-oxazolinen |
| FR1543534A (fr) * | 1966-09-27 | 1968-10-25 | Bayer Ag | Procédé de fabrication de 2-phénylimino-oxazolidines |
| FR1543535A (fr) * | 1966-09-27 | 1968-10-25 | Bayer Ag | Procédé de fabrication de 2-phénylamino-2-oxazolines |
-
1975
- 1975-11-21 CH CH1516475A patent/CH623044A5/de not_active IP Right Cessation
- 1975-11-25 BE BE162139A patent/BE835899A/xx unknown
- 1975-11-26 AT AT898575A patent/AT357557B/de not_active IP Right Cessation
- 1975-11-26 IE IE2578/75A patent/IE42759B1/en unknown
- 1975-11-26 AU AU86989/75A patent/AU501512B2/en not_active Ceased
- 1975-11-26 DE DE19752552933 patent/DE2552933A1/de not_active Withdrawn
- 1975-11-26 GB GB48640/75A patent/GB1507340A/en not_active Expired
- 1975-11-26 NL NL7513804A patent/NL7513804A/xx not_active Application Discontinuation
- 1975-11-26 ZA ZA757457A patent/ZA757457B/xx unknown
- 1975-11-26 NO NO753984A patent/NO146497C/no unknown
- 1975-11-26 FI FI753332A patent/FI753332A7/fi not_active Application Discontinuation
- 1975-11-26 AR AR261362A patent/AR219478A1/es active
- 1975-11-26 CA CA240,512A patent/CA1063112A/en not_active Expired
- 1975-11-26 FR FR7536178A patent/FR2346000A1/fr active Granted
- 1975-11-26 SE SE7513331A patent/SE7513331L/xx not_active Application Discontinuation
- 1975-11-26 PH PH17810A patent/PH14474A/en unknown
- 1975-11-27 IL IL48557A patent/IL48557A/xx unknown
- 1975-11-27 JP JP50141811A patent/JPS5182239A/ja active Pending
- 1975-11-27 DK DK535275A patent/DK535275A/da not_active Application Discontinuation
- 1975-11-27 LU LU73888A patent/LU73888A1/xx unknown
- 1975-12-01 PL PL1975185156A patent/PL99122B1/pl unknown
- 1975-12-01 SU SU752194050A patent/SU655311A3/ru active
- 1975-12-01 PL PL1975193580A patent/PL102327B1/pl unknown
- 1975-12-01 CS CS758133A patent/CS188259B2/cs unknown
- 1975-12-01 HU HU75SCHE549A patent/HU175541B/hu unknown
- 1975-12-01 DD DD189793A patent/DD124730A5/xx unknown
- 1975-12-02 IT IT29923/75A patent/IT1051024B/it active
-
1976
- 1976-10-20 AR AR265154A patent/AR218436A1/es active
- 1976-10-26 SU SU762414458A patent/SU685146A3/ru active
-
1980
- 1980-06-11 SE SE8004364A patent/SE8004364L/sv unknown
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000054759A3 (en) * | 1999-03-15 | 2001-02-15 | Tularik Inc | Lxr modulators |
| US6316503B1 (en) | 1999-03-15 | 2001-11-13 | Tularik Inc. | LXR modulators |
| US7071358B2 (en) | 2002-01-30 | 2006-07-04 | Amgen Inc. | Arylsulfonamidobenzylic compounds |
| US7112606B2 (en) | 2002-01-30 | 2006-09-26 | Amgen Inc. | Heterocyclic arylsulfonamidobenzylic compounds |
| US7326812B2 (en) | 2002-01-30 | 2008-02-05 | Amgen Inc. | Arylsulfonamidobenzylic compounds |
| US7473703B2 (en) | 2002-01-30 | 2009-01-06 | Amgen Inc. | Heterocyclic arylsulfonamidobenzylic compounds |
| WO2003089404A1 (en) * | 2002-04-19 | 2003-10-30 | Abbott Laboratories | Naphthalene amides as potassium channel openers |
| CN107108485A (zh) * | 2014-10-24 | 2017-08-29 | 小野药品工业株式会社 | Kcnq2～5通道活化剂 |
| US9809544B2 (en) | 2014-10-24 | 2017-11-07 | Ono Pharmaceutical Co., Ltd. | KCNQ2-5 channel activator |
| US10196358B2 (en) | 2014-10-24 | 2019-02-05 | Ono Pharmaceutical Co., Ltd. | KCNQ2-5 channel activator |
| US10676438B2 (en) | 2014-10-24 | 2020-06-09 | Ono Pharmaceutical Co., Ltd. | KCNQ2-5 channel activator |
| CN107108485B (zh) * | 2014-10-24 | 2020-06-12 | 小野药品工业株式会社 | Kcnq2～5通道活化剂 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |