GB1503551A - 4-piperidylureas - Google Patents

4-piperidylureas

Info

Publication number
GB1503551A
GB1503551A GB20695/75A GB2069575A GB1503551A GB 1503551 A GB1503551 A GB 1503551A GB 20695/75 A GB20695/75 A GB 20695/75A GB 2069575 A GB2069575 A GB 2069575A GB 1503551 A GB1503551 A GB 1503551A
Authority
GB
United Kingdom
Prior art keywords
group
piperidyl
formula
novel
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB20695/75A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Boehringer Ingelheim GmbH
Original Assignee
CH Boehringer Sohn AG and Co KG
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG, Boehringer Ingelheim GmbH filed Critical CH Boehringer Sohn AG and Co KG
Publication of GB1503551A publication Critical patent/GB1503551A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Novel 1-[N-(p-fluorobenzoylpropyl)-4-piperidyl]ureas of the formula I below, in which R is a hydrogen atom, an acetyl group, an alkyl group with 1 to 3 carbon atoms or the phenyl group, are prepared by reacting a correspondingly substituted N-(4-piperidyl)-2-imidazolidinone with a p-fluorobutyrophenone which has in the omega position a group which can be eliminated under the reaction conditions. The products of the process can be converted into their physiologically tolerated acid addition salts. It is additionally possible for resulting compounds of the formula I in which R is hydrogen to be acetylated by reaction with acetyl chloride or acetic anhydride. The novel compounds show the typical range of effects of the neuroleptics and can therefore be employed as CNS-depressant agents, sedatives and tranquillizers. <IMAGE>
GB20695/75A 1974-05-16 1975-05-15 4-piperidylureas Expired GB1503551A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2423896A DE2423896A1 (en) 1974-05-16 1974-05-16 NEW SINGLE SQUARE BRACKETS ON N- (P-FLUOROBENZOYLPROPYL) -4-PIPERIDYL SQUARE BRACKETS FOR -UURA AND METHOD FOR MANUFACTURING IT

Publications (1)

Publication Number Publication Date
GB1503551A true GB1503551A (en) 1978-03-15

Family

ID=5915759

Family Applications (1)

Application Number Title Priority Date Filing Date
GB20695/75A Expired GB1503551A (en) 1974-05-16 1975-05-15 4-piperidylureas

Country Status (13)

Country Link
JP (1) JPS50160280A (en)
AT (1) AT343673B (en)
BE (1) BE829139A (en)
CH (1) CH613448A5 (en)
DE (1) DE2423896A1 (en)
DK (1) DK213575A (en)
ES (2) ES437081A1 (en)
FI (1) FI59407C (en)
FR (1) FR2270876B1 (en)
GB (1) GB1503551A (en)
NL (1) NL7505711A (en)
NO (1) NO142348C (en)
SE (1) SE413504B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001032649A1 (en) * 1999-10-29 2001-05-10 Boehringer Ingelheim Pharma Kg Arylalkane, arylalkene and aryl azaalkane, medicaments containing said compounds and method for the production thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6838858B2 (en) 2001-10-29 2005-01-04 Visteon Global Technologies, Inc. Power management system and method for an automobile

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001032649A1 (en) * 1999-10-29 2001-05-10 Boehringer Ingelheim Pharma Kg Arylalkane, arylalkene and aryl azaalkane, medicaments containing said compounds and method for the production thereof
US7230001B1 (en) 1999-10-29 2007-06-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Arylalkane, arylalkene and aryl azaalkane, medicaments containing said compounds and method for the production thereof

Also Published As

Publication number Publication date
NO142348C (en) 1980-08-06
FI59407C (en) 1981-08-10
ES441439A1 (en) 1977-03-01
NL7505711A (en) 1975-11-18
ATA310375A (en) 1977-10-15
SE413504B (en) 1980-06-02
BE829139A (en) 1975-11-17
FI751333A (en) 1975-11-17
DE2423896A1 (en) 1975-11-27
NO751725L (en) 1975-11-18
FI59407B (en) 1981-04-30
ES437081A1 (en) 1977-01-16
DK213575A (en) 1975-11-17
AT343673B (en) 1978-06-12
AU8119675A (en) 1976-11-18
FR2270876A1 (en) 1975-12-12
JPS50160280A (en) 1975-12-25
FR2270876B1 (en) 1980-01-25
NO142348B (en) 1980-04-28
SE7505586L (en) 1975-11-17
CH613448A5 (en) 1979-09-28

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee