ES465567A1 - 2-amino-cyclopent-1-ene-1-thiocarboxylic acid-disulphides and a process for the preparation thereof - Google Patents

2-amino-cyclopent-1-ene-1-thiocarboxylic acid-disulphides and a process for the preparation thereof

Info

Publication number
ES465567A1
ES465567A1 ES465567A ES465567A ES465567A1 ES 465567 A1 ES465567 A1 ES 465567A1 ES 465567 A ES465567 A ES 465567A ES 465567 A ES465567 A ES 465567A ES 465567 A1 ES465567 A1 ES 465567A1
Authority
ES
Spain
Prior art keywords
amino
carbon atoms
cyclopent
ene
disulphides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES465567A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES465567A1 publication Critical patent/ES465567A1/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel N-substituted 2-amino-cyclopent-1-ene-1-dithiocarboxylic acids of the general formula < IMAGE > in which R denotes an unsubstituted straight or branched alkyl group having 5 or 6 carbon atoms, an alkyl group having 1 to 6 carbon atoms, which is substituted by alkoxy groups having 1 to 4 carbon atoms, or by hydroxyl, carboxyl and/or amino groups, an alkenyl group having 2 to 4 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, or a phenyl group, are prepared by reacting 2-amino-cyclopent-1-ene-1-dithiocarboxylic acid with amines of the general formula NH2-R. The novel compounds have a dopamine- beta -hydroxylase-inhibiting effect.
ES465567A 1976-12-30 1977-12-29 2-amino-cyclopent-1-ene-1-thiocarboxylic acid-disulphides and a process for the preparation thereof Expired ES465567A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU76RI610A HU175526B (en) 1976-12-30 1976-12-30 Process for producing 2-amino-cyclopent-1-2n2-1-dithiocarboxylic acid -disulfides

Publications (1)

Publication Number Publication Date
ES465567A1 true ES465567A1 (en) 1979-01-01

Family

ID=11001014

Family Applications (1)

Application Number Title Priority Date Filing Date
ES465567A Expired ES465567A1 (en) 1976-12-30 1977-12-29 2-amino-cyclopent-1-ene-1-thiocarboxylic acid-disulphides and a process for the preparation thereof

Country Status (21)

Country Link
JP (1) JPS5384949A (en)
AR (1) AR216308A1 (en)
AT (1) AT351501B (en)
AU (1) AU516353B2 (en)
BE (1) BE862408A (en)
CH (1) CH631701A5 (en)
DE (1) DE2758809A1 (en)
ES (1) ES465567A1 (en)
FI (1) FI66595C (en)
FR (1) FR2376132A1 (en)
GB (1) GB1582716A (en)
HU (1) HU175526B (en)
IL (1) IL53646A (en)
IN (1) IN146470B (en)
NL (1) NL7714514A (en)
NO (1) NO145237C (en)
PT (1) PT67482B (en)
SE (1) SE7714526L (en)
SU (1) SU743580A3 (en)
YU (1) YU309677A (en)
ZA (1) ZA777573B (en)

Also Published As

Publication number Publication date
AR216308A1 (en) 1979-12-14
AU3197977A (en) 1979-06-28
BE862408A (en) 1978-04-14
PT67482A (en) 1978-01-01
ZA777573B (en) 1978-10-25
SE7714526L (en) 1978-07-01
ATA912077A (en) 1979-01-15
HU175526B (en) 1980-08-28
IN146470B (en) 1979-06-09
PT67482B (en) 1979-05-30
FI773967A (en) 1978-07-01
FR2376132B1 (en) 1979-10-19
AU516353B2 (en) 1981-05-28
NO145237B (en) 1981-11-02
DE2758809A1 (en) 1978-07-06
YU309677A (en) 1983-01-21
IL53646A (en) 1982-03-31
NO774502L (en) 1978-07-03
SU743580A3 (en) 1980-06-25
NL7714514A (en) 1978-07-04
AT351501B (en) 1979-07-25
GB1582716A (en) 1981-01-14
JPS5384949A (en) 1978-07-26
FI66595B (en) 1984-07-31
FR2376132A1 (en) 1978-07-28
NO145237C (en) 1982-02-10
CH631701A5 (en) 1982-08-31
IL53646A0 (en) 1978-03-10
FI66595C (en) 1984-11-12

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