GB1501153A - Pharmaceutically active amines - Google Patents
Pharmaceutically active aminesInfo
- Publication number
- GB1501153A GB1501153A GB15514/75A GB1551475A GB1501153A GB 1501153 A GB1501153 A GB 1501153A GB 15514/75 A GB15514/75 A GB 15514/75A GB 1551475 A GB1551475 A GB 1551475A GB 1501153 A GB1501153 A GB 1501153A
- Authority
- GB
- United Kingdom
- Prior art keywords
- trimethoxybenzyl
- trimethyl
- chloride
- compound
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001412 amines Chemical class 0.000 title 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- UMVJFCZSLLVFMI-UHFFFAOYSA-N 1,4,5-trimethyl-3,6-dihydro-2h-pyridine Chemical compound CN1CCC(C)=C(C)C1 UMVJFCZSLLVFMI-UHFFFAOYSA-N 0.000 abstract 1
- XXRUQNNAKXZSOS-UHFFFAOYSA-N 5-(chloromethyl)-1,2,3-trimethoxybenzene Chemical compound COC1=CC(CCl)=CC(OC)=C1OC XXRUQNNAKXZSOS-UHFFFAOYSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 229910000000 metal hydroxide Inorganic materials 0.000 abstract 1
- 150000004692 metal hydroxides Chemical class 0.000 abstract 1
- MJFWGIGCSSZKIY-UHFFFAOYSA-N n,2,3-trimethyl-n-[(3,4,5-trimethoxyphenyl)methyl]penta-2,4-dien-1-amine Chemical compound COC1=CC(CN(C)CC(C)=C(C)C=C)=CC(OC)=C1OC MJFWGIGCSSZKIY-UHFFFAOYSA-N 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES425970A ES425970A1 (es) | 1974-05-04 | 1974-05-04 | Un procedimiento para la obtencion de n - metil - n-(3,4,5-trimeboxibencil)-2,3-dimetil-2,4-pentadienamina. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1501153A true GB1501153A (en) | 1978-02-15 |
Family
ID=8466594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB15514/75A Expired GB1501153A (en) | 1974-05-04 | 1975-04-15 | Pharmaceutically active amines |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5337337B2 (enExample) |
| AR (1) | AR206623A1 (enExample) |
| AT (1) | AT337160B (enExample) |
| AU (1) | AU8050775A (enExample) |
| BE (1) | BE828240A (enExample) |
| CA (1) | CA1052794A (enExample) |
| CH (1) | CH615150A5 (enExample) |
| DE (1) | DE2518534A1 (enExample) |
| ES (1) | ES425970A1 (enExample) |
| FR (1) | FR2269336B1 (enExample) |
| GB (1) | GB1501153A (enExample) |
| NL (1) | NL7505254A (enExample) |
| SE (1) | SE412755B (enExample) |
| SU (1) | SU562192A3 (enExample) |
-
1974
- 1974-05-04 ES ES425970A patent/ES425970A1/es not_active Expired
-
1975
- 1975-01-01 AR AR257859A patent/AR206623A1/es active
- 1975-03-07 AT AT181075A patent/AT337160B/de not_active IP Right Cessation
- 1975-04-15 SE SE7504301A patent/SE412755B/xx unknown
- 1975-04-15 GB GB15514/75A patent/GB1501153A/en not_active Expired
- 1975-04-22 BE BE155654A patent/BE828240A/xx unknown
- 1975-04-24 AU AU80507/75A patent/AU8050775A/en not_active Expired
- 1975-04-25 DE DE19752518534 patent/DE2518534A1/de active Pending
- 1975-04-30 FR FR7513536A patent/FR2269336B1/fr not_active Expired
- 1975-05-01 CA CA226,057A patent/CA1052794A/en not_active Expired
- 1975-05-02 CH CH568075A patent/CH615150A5/de not_active IP Right Cessation
- 1975-05-02 NL NL7505254A patent/NL7505254A/xx not_active Application Discontinuation
- 1975-05-02 JP JP5380075A patent/JPS5337337B2/ja not_active Expired
- 1975-05-04 SU SU2129803A patent/SU562192A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| FR2269336B1 (enExample) | 1977-09-09 |
| SU562192A3 (ru) | 1977-06-15 |
| JPS50151835A (enExample) | 1975-12-06 |
| FR2269336A1 (enExample) | 1975-11-28 |
| DE2518534A1 (de) | 1975-11-13 |
| ATA181075A (de) | 1976-10-15 |
| CA1052794A (en) | 1979-04-17 |
| AU8050775A (en) | 1976-10-28 |
| BE828240A (fr) | 1975-10-22 |
| AT337160B (de) | 1977-06-10 |
| JPS5337337B2 (enExample) | 1978-10-07 |
| ES425970A1 (es) | 1976-09-16 |
| NL7505254A (nl) | 1975-11-06 |
| CH615150A5 (en) | 1980-01-15 |
| SE7504301L (sv) | 1975-11-05 |
| SE412755B (sv) | 1980-03-17 |
| AR206623A1 (es) | 1976-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |