ES425970A1 - Un procedimiento para la obtencion de n - metil - n-(3,4,5-trimeboxibencil)-2,3-dimetil-2,4-pentadienamina. - Google Patents
Un procedimiento para la obtencion de n - metil - n-(3,4,5-trimeboxibencil)-2,3-dimetil-2,4-pentadienamina.Info
- Publication number
- ES425970A1 ES425970A1 ES425970A ES425970A ES425970A1 ES 425970 A1 ES425970 A1 ES 425970A1 ES 425970 A ES425970 A ES 425970A ES 425970 A ES425970 A ES 425970A ES 425970 A1 ES425970 A1 ES 425970A1
- Authority
- ES
- Spain
- Prior art keywords
- trimethoxybenzyl
- trimethyl
- chloride
- compound
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001412 amines Chemical class 0.000 title 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- UMVJFCZSLLVFMI-UHFFFAOYSA-N 1,4,5-trimethyl-3,6-dihydro-2h-pyridine Chemical compound CN1CCC(C)=C(C)C1 UMVJFCZSLLVFMI-UHFFFAOYSA-N 0.000 abstract 1
- XXRUQNNAKXZSOS-UHFFFAOYSA-N 5-(chloromethyl)-1,2,3-trimethoxybenzene Chemical compound COC1=CC(CCl)=CC(OC)=C1OC XXRUQNNAKXZSOS-UHFFFAOYSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 229910000000 metal hydroxide Inorganic materials 0.000 abstract 1
- 150000004692 metal hydroxides Chemical class 0.000 abstract 1
- MJFWGIGCSSZKIY-UHFFFAOYSA-N n,2,3-trimethyl-n-[(3,4,5-trimethoxyphenyl)methyl]penta-2,4-dien-1-amine Chemical compound COC1=CC(CN(C)CC(C)=C(C)C=C)=CC(OC)=C1OC MJFWGIGCSSZKIY-UHFFFAOYSA-N 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES425970A ES425970A1 (es) | 1974-05-04 | 1974-05-04 | Un procedimiento para la obtencion de n - metil - n-(3,4,5-trimeboxibencil)-2,3-dimetil-2,4-pentadienamina. |
| AR257859A AR206623A1 (es) | 1974-05-04 | 1975-01-01 | Un procedimiento para la obtencion de n-metil n-(3,4,5-trimetoxibencil)-2,3,-dimetil-2,4-pentadienamina |
| AT181075A AT337160B (de) | 1974-05-04 | 1975-03-07 | Verfahren zur herstellung des neuen n-methyl-n-(3,4,5-trimethoxybenzyl)-2,3-dimethyl-2,4-pentadienamins und seinen saureadditionssalzen |
| SE7504301A SE412755B (sv) | 1974-05-04 | 1975-04-15 | Sett att framstella n-metyl-n-(3,4,5-teimetoxibensyl)-2,3-dimetyl-2,4pentadienamin |
| GB15514/75A GB1501153A (en) | 1974-05-04 | 1975-04-15 | Pharmaceutically active amines |
| BE155654A BE828240A (fr) | 1974-05-04 | 1975-04-22 | Preparation de la n-methyl-n- (3,4,5- trimethoxybenzyl)-2,3-dimethyl-2,4-pentadienamine |
| AU80507/75A AU8050775A (en) | 1974-05-04 | 1975-04-24 | A method of producing n-methyl-n-%3,4,5-trimethoxybenzyl<-2,3dimethyl-2,4-pentadienamine |
| DE19752518534 DE2518534A1 (de) | 1974-05-04 | 1975-04-25 | N-methyl-n-(3,4,5-trimethoxybenzyl) -2,3-dimethyl-2,4-pentadienamine, verfahren zu ihrer herstellung sowie sie enthaltende arzneimittel |
| FR7513536A FR2269336B1 (enExample) | 1974-05-04 | 1975-04-30 | |
| CA226,057A CA1052794A (en) | 1974-05-04 | 1975-05-01 | Method of producing n-methyl-n-(3,4,5-trimethoxybenzyl)-2,3-dimethyl-2,4-pentadienamine |
| JP5380075A JPS5337337B2 (enExample) | 1974-05-04 | 1975-05-02 | |
| CH568075A CH615150A5 (en) | 1974-05-04 | 1975-05-02 | Process for the preparation of N-methyl-N-(3,4,5-trimethoxybenzyl)-2,3-dimethyl-2,4-pentadiene- amine |
| NL7505254A NL7505254A (nl) | 1974-05-04 | 1975-05-02 | Werkwijze voor het bereiden van geneesmiddelen en werkwijze voor het bereiden van nieuwe trimethoxy- benzylverbindingen. |
| SU2129803A SU562192A3 (ru) | 1974-05-04 | 1975-05-04 | Способ получени -метил- (3,4,5-триметоксибензил)-2,3диметил-2,4-пентадиенамина или его солей |
| US05/662,577 US4028371A (en) | 1974-05-04 | 1976-03-01 | The compound 1,3,4-trimethyl-1-(3,4,5-trimethoxybenzyl)-1,2,5,6-tetrahydropyridine chloride |
| AT479676A AT340924B (de) | 1974-05-04 | 1976-06-30 | Verfahren zur herstellung des neuen 1,3,4-trimethyl-1- (3',4',5'-trimethoxybenzyl)- 1,2,5,6-tetrahydropyridiniumchlorids |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES425970A ES425970A1 (es) | 1974-05-04 | 1974-05-04 | Un procedimiento para la obtencion de n - metil - n-(3,4,5-trimeboxibencil)-2,3-dimetil-2,4-pentadienamina. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES425970A1 true ES425970A1 (es) | 1976-09-16 |
Family
ID=8466594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES425970A Expired ES425970A1 (es) | 1974-05-04 | 1974-05-04 | Un procedimiento para la obtencion de n - metil - n-(3,4,5-trimeboxibencil)-2,3-dimetil-2,4-pentadienamina. |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5337337B2 (enExample) |
| AR (1) | AR206623A1 (enExample) |
| AT (1) | AT337160B (enExample) |
| AU (1) | AU8050775A (enExample) |
| BE (1) | BE828240A (enExample) |
| CA (1) | CA1052794A (enExample) |
| CH (1) | CH615150A5 (enExample) |
| DE (1) | DE2518534A1 (enExample) |
| ES (1) | ES425970A1 (enExample) |
| FR (1) | FR2269336B1 (enExample) |
| GB (1) | GB1501153A (enExample) |
| NL (1) | NL7505254A (enExample) |
| SE (1) | SE412755B (enExample) |
| SU (1) | SU562192A3 (enExample) |
-
1974
- 1974-05-04 ES ES425970A patent/ES425970A1/es not_active Expired
-
1975
- 1975-01-01 AR AR257859A patent/AR206623A1/es active
- 1975-03-07 AT AT181075A patent/AT337160B/de not_active IP Right Cessation
- 1975-04-15 SE SE7504301A patent/SE412755B/xx unknown
- 1975-04-15 GB GB15514/75A patent/GB1501153A/en not_active Expired
- 1975-04-22 BE BE155654A patent/BE828240A/xx unknown
- 1975-04-24 AU AU80507/75A patent/AU8050775A/en not_active Expired
- 1975-04-25 DE DE19752518534 patent/DE2518534A1/de active Pending
- 1975-04-30 FR FR7513536A patent/FR2269336B1/fr not_active Expired
- 1975-05-01 CA CA226,057A patent/CA1052794A/en not_active Expired
- 1975-05-02 CH CH568075A patent/CH615150A5/de not_active IP Right Cessation
- 1975-05-02 NL NL7505254A patent/NL7505254A/xx not_active Application Discontinuation
- 1975-05-02 JP JP5380075A patent/JPS5337337B2/ja not_active Expired
- 1975-05-04 SU SU2129803A patent/SU562192A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| FR2269336B1 (enExample) | 1977-09-09 |
| SU562192A3 (ru) | 1977-06-15 |
| JPS50151835A (enExample) | 1975-12-06 |
| FR2269336A1 (enExample) | 1975-11-28 |
| DE2518534A1 (de) | 1975-11-13 |
| ATA181075A (de) | 1976-10-15 |
| CA1052794A (en) | 1979-04-17 |
| AU8050775A (en) | 1976-10-28 |
| BE828240A (fr) | 1975-10-22 |
| AT337160B (de) | 1977-06-10 |
| JPS5337337B2 (enExample) | 1978-10-07 |
| NL7505254A (nl) | 1975-11-06 |
| CH615150A5 (en) | 1980-01-15 |
| GB1501153A (en) | 1978-02-15 |
| SE7504301L (sv) | 1975-11-05 |
| SE412755B (sv) | 1980-03-17 |
| AR206623A1 (es) | 1976-08-06 |
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