GB1496561A - Microbial amylase-inhibitor and preparation thereof - Google Patents
Microbial amylase-inhibitor and preparation thereofInfo
- Publication number
- GB1496561A GB1496561A GB10967/75A GB1096775A GB1496561A GB 1496561 A GB1496561 A GB 1496561A GB 10967/75 A GB10967/75 A GB 10967/75A GB 1096775 A GB1096775 A GB 1096775A GB 1496561 A GB1496561 A GB 1496561A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amylase
- range
- diastaticus
- march
- aqueous solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003392 amylase inhibitor Substances 0.000 title abstract 5
- 229940122816 Amylase inhibitor Drugs 0.000 title abstract 3
- 230000000813 microbial effect Effects 0.000 title 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 229910052799 carbon Inorganic materials 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
- 241000187091 Streptomyces diastaticus Species 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 2
- 238000002523 gelfiltration Methods 0.000 abstract 2
- IOLCXVTUBQKXJR-UHFFFAOYSA-M potassium bromide Chemical compound [K+].[Br-] IOLCXVTUBQKXJR-UHFFFAOYSA-M 0.000 abstract 2
- 239000004382 Amylase Substances 0.000 abstract 1
- 108090000317 Chymotrypsin Proteins 0.000 abstract 1
- 108010073178 Glucan 1,4-alpha-Glucosidase Proteins 0.000 abstract 1
- 102100022624 Glucoamylase Human genes 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 108010028688 Isoamylase Proteins 0.000 abstract 1
- 108090000526 Papain Proteins 0.000 abstract 1
- 108090000284 Pepsin A Proteins 0.000 abstract 1
- 102000057297 Pepsin A Human genes 0.000 abstract 1
- 239000001888 Peptone Substances 0.000 abstract 1
- 108010080698 Peptones Proteins 0.000 abstract 1
- 239000004365 Protease Substances 0.000 abstract 1
- 229920002472 Starch Polymers 0.000 abstract 1
- 108090000631 Trypsin Proteins 0.000 abstract 1
- 102000004142 Trypsin Human genes 0.000 abstract 1
- 238000000862 absorption spectrum Methods 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 102000004139 alpha-Amylases Human genes 0.000 abstract 1
- 108090000637 alpha-Amylases Proteins 0.000 abstract 1
- 229940024171 alpha-amylase Drugs 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 229960002376 chymotrypsin Drugs 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000000415 inactivating effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 235000013372 meat Nutrition 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 229940055729 papain Drugs 0.000 abstract 1
- 235000019834 papain Nutrition 0.000 abstract 1
- 229940111202 pepsin Drugs 0.000 abstract 1
- 235000019319 peptone Nutrition 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
- 229960001322 trypsin Drugs 0.000 abstract 1
- 239000012588 trypsin Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP49029646A JPS5221596B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-03-15 | 1974-03-15 | |
JP49029647A JPS5221597B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-03-15 | 1974-03-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1496561A true GB1496561A (en) | 1977-12-30 |
Family
ID=26367871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB10967/75A Expired GB1496561A (en) | 1974-03-15 | 1975-03-17 | Microbial amylase-inhibitor and preparation thereof |
Country Status (3)
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4226764A (en) | 1977-01-19 | 1980-10-07 | Hoechst Aktiengesellschaft | α-Amylase inhibitor from a streptomycete and process for its preparation |
RU2355755C1 (ru) * | 2008-01-09 | 2009-05-20 | Государственное учреждение Всероссийский научно-исследовательский институт пищевых ароматизаторов, кислот и красителей Российской академии сельскохозяйственных наук (ГУ ВНИИПАКК) | ШТАММ АКТИНОМИЦЕТА Streptomyces lucensis - ПРОДУЦЕНТ ИНГИБИТОРА ГЛИКОЗИДАЗ |
RU2495930C1 (ru) * | 2012-06-27 | 2013-10-20 | Государственное научное учреждение Всероссийский научно-исследовательский институт пищевых ароматизаторов, кислот и красителей Российской академии сельскохозяйственных наук (ГНУ ВНИИПАКК Россельхозакадемии) | Способ получения ингибитора гликозидаз |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5953920B2 (ja) * | 1977-12-28 | 1984-12-27 | 東洋醸造株式会社 | 新規なアミノ糖化合物およびその製法 |
GB2016497A (en) * | 1978-02-10 | 1979-09-26 | Taisho Pharmaceutical Co Ltd | Microbiological production of amylase inhibitor |
JPS5910193B2 (ja) * | 1980-06-04 | 1984-03-07 | 富士レビオ株式会社 | アミラ−ゼ阻害物質ai−bの製造法 |
US4757001A (en) * | 1984-02-16 | 1988-07-12 | Fujirebio Kabushiki Kaisha | Method of measuring biological ligand by utilizing amylase |
JP2920402B2 (ja) * | 1990-04-06 | 1999-07-19 | 協同乳業株式会社 | 大豆由来アミラーゼインヒビター及びその製造法 |
JPH05279374A (ja) * | 1992-03-31 | 1993-10-26 | Sawao Murao | スイダトレスチン及びその製造方法 |
CA2236641C (en) * | 1997-05-07 | 2008-07-15 | Cornell Research Foundation, Inc. | Preparation of fagopyritols and uses therefor |
US6492341B1 (en) | 1997-05-07 | 2002-12-10 | Cornell Research Foundation, Inc. | Preparation of fagopyritols and uses therefor |
GB9921229D0 (en) * | 1999-09-08 | 1999-11-10 | Med Eq As | Compositions |
US7713546B1 (en) * | 2001-04-03 | 2010-05-11 | Soft Gel Technologies, Inc. | Corosolic acid formulation and its application for weight-loss management and blood sugar balance |
CA2483550C (en) | 2002-05-09 | 2016-06-28 | Cornell Research Foundation, Inc. | Fagopyrum esculentum fagopyritol synthase gene and use thereof |
US7108869B2 (en) * | 2002-11-07 | 2006-09-19 | Access Business Group International Llc | Nutritional supplement containing alpha-glucosidase and alpha-amylase inhibitors |
US20060051435A1 (en) * | 2004-08-19 | 2006-03-09 | Udell Ronald G | Nutritional supplement for body fat reduction |
US20070104805A1 (en) * | 2005-11-01 | 2007-05-10 | Udell Ronald G | Compositions of Hoodia Gordonii and Pinolenic Acid Derivatives |
RU2346042C2 (ru) * | 2006-10-30 | 2009-02-10 | Государственное учреждение Всероссийский научно-исследовательский институт пищевых ароматизаторов, кислот и красителей Российской академии сельскохозяйственных наук (ГУ ВНИИПАКК) | Штамм актиномицета streptomyces violaceus - продуцент ингибитора гликозидаз |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2064092C2 (de) * | 1970-12-28 | 1983-06-01 | Bayer Ag, 5090 Leverkusen | Inhibitoren für Glykosidhydrolasen aus Actinomyceten |
JPS5111197B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1971-05-31 | 1976-04-09 | ||
DE2209832C3 (de) * | 1972-03-01 | 1979-03-29 | Bayer Ag, 5090 Leverkusen | Herstellung von Saccharaseinhibitoren |
DE2209833C3 (de) * | 1972-03-01 | 1978-06-01 | Bayer Ag, 5090 Leverkusen | Herstellung eines Amylaseinhibitors |
-
1975
- 1975-03-12 US US05/557,555 patent/US4010258A/en not_active Expired - Lifetime
- 1975-03-13 FR FR7507942A patent/FR2263785B1/fr not_active Expired
- 1975-03-17 GB GB10967/75A patent/GB1496561A/en not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4226764A (en) | 1977-01-19 | 1980-10-07 | Hoechst Aktiengesellschaft | α-Amylase inhibitor from a streptomycete and process for its preparation |
RU2355755C1 (ru) * | 2008-01-09 | 2009-05-20 | Государственное учреждение Всероссийский научно-исследовательский институт пищевых ароматизаторов, кислот и красителей Российской академии сельскохозяйственных наук (ГУ ВНИИПАКК) | ШТАММ АКТИНОМИЦЕТА Streptomyces lucensis - ПРОДУЦЕНТ ИНГИБИТОРА ГЛИКОЗИДАЗ |
RU2495930C1 (ru) * | 2012-06-27 | 2013-10-20 | Государственное научное учреждение Всероссийский научно-исследовательский институт пищевых ароматизаторов, кислот и красителей Российской академии сельскохозяйственных наук (ГНУ ВНИИПАКК Россельхозакадемии) | Способ получения ингибитора гликозидаз |
Also Published As
Publication number | Publication date |
---|---|
US4010258A (en) | 1977-03-01 |
FR2263785A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-10-10 |
FR2263785B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1978-12-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |