GB1492837A - Insulin preparations having antidiabetic activity and process for their manufacture - Google Patents
Insulin preparations having antidiabetic activity and process for their manufactureInfo
- Publication number
- GB1492837A GB1492837A GB14079/75A GB1407975A GB1492837A GB 1492837 A GB1492837 A GB 1492837A GB 14079/75 A GB14079/75 A GB 14079/75A GB 1407975 A GB1407975 A GB 1407975A GB 1492837 A GB1492837 A GB 1492837A
- Authority
- GB
- United Kingdom
- Prior art keywords
- insulin
- manufacture
- insulin preparations
- zinc ion
- phenylalanine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
1492837 Sustained release insulin preparations HOECHST AG 7 April 1975 [13 April 1974 17 Dec 1974] 14079/75 Heading A5B Sustained release insulin preparations comprise (1) an aqueous medium, (2) a crystalline insulin, (3) dissolved des-phenylalanine <SP>B1</SP>-insulin of the same species and (4) 25 to 80 meg of zinc ion per 100 I.U. of insulin. The insulin and insulin derivative may be bovine or porcine. The zinc ion may be present as zinc chloride. The preparation may be made by mixing a suspension of insulin crystals containing zinc ion with a solution of des-phenylalanine-insulin also containing zinc ions and adjusting the pH to the required range.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2418218A DE2418218A1 (en) | 1974-04-13 | 1974-04-13 | Long acting insulin compstns - contg. a crystalline insulin suspension and des phenyl alanine insulin soln. |
DE19742459515 DE2459515C3 (en) | 1974-12-17 | 1974-12-17 | Medicinal preparations with an antidiabetic effect |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1492837A true GB1492837A (en) | 1977-11-23 |
Family
ID=25766977
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB14079/75A Expired GB1492837A (en) | 1974-04-13 | 1975-04-07 | Insulin preparations having antidiabetic activity and process for their manufacture |
Country Status (11)
Country | Link |
---|---|
AU (1) | AU500430B2 (en) |
CA (1) | CA1047919A (en) |
EG (1) | EG12098A (en) |
ES (1) | ES436398A1 (en) |
FI (1) | FI751084A (en) |
FR (1) | FR2267116B1 (en) |
GB (1) | GB1492837A (en) |
IE (1) | IE40985B1 (en) |
IL (1) | IL47043A (en) |
LU (1) | LU72269A1 (en) |
NL (1) | NL7504165A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5028587A (en) * | 1987-05-22 | 1991-07-02 | Hoechst Aktiengesellschaft | Mixed crystals of insulin and insulin derivatives |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1560232A (en) * | 1977-02-01 | 1980-01-30 | Novo Industri As | Biphasic insulin preparations comprising crystalline insulin and monodesamido insulin |
WO1997005166A1 (en) | 1995-07-25 | 1997-02-13 | Novartis Ag | Transforming growth factor beta crystals |
-
1975
- 1975-03-31 EG EG178/75A patent/EG12098A/en active
- 1975-04-07 GB GB14079/75A patent/GB1492837A/en not_active Expired
- 1975-04-07 IL IL47043A patent/IL47043A/en unknown
- 1975-04-08 ES ES436398A patent/ES436398A1/en not_active Expired
- 1975-04-08 NL NL7504165A patent/NL7504165A/en not_active Application Discontinuation
- 1975-04-10 FI FI751084A patent/FI751084A/fi not_active Application Discontinuation
- 1975-04-11 LU LU72269A patent/LU72269A1/xx unknown
- 1975-04-11 AU AU80073/75A patent/AU500430B2/en not_active Expired
- 1975-04-11 IE IE832/75A patent/IE40985B1/en unknown
- 1975-04-11 CA CA224,590A patent/CA1047919A/en not_active Expired
- 1975-04-14 FR FR7511535A patent/FR2267116B1/fr not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5028587A (en) * | 1987-05-22 | 1991-07-02 | Hoechst Aktiengesellschaft | Mixed crystals of insulin and insulin derivatives |
Also Published As
Publication number | Publication date |
---|---|
CA1047919A (en) | 1979-02-06 |
AU8007375A (en) | 1976-10-14 |
IE40985B1 (en) | 1979-09-26 |
IL47043A0 (en) | 1975-06-25 |
NL7504165A (en) | 1975-10-15 |
IE40985L (en) | 1975-10-13 |
FI751084A (en) | 1975-10-14 |
FR2267116A1 (en) | 1975-11-07 |
IL47043A (en) | 1978-06-15 |
EG12098A (en) | 1980-12-31 |
ES436398A1 (en) | 1977-05-01 |
AU500430B2 (en) | 1979-05-24 |
FR2267116B1 (en) | 1978-10-06 |
LU72269A1 (en) | 1977-02-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |