ES452786A3 - A procedure for the production of insulin preparations with a prolonged effect. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the production of insulin preparations with a prolonged effect. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES452786A3 ES452786A3 ES452786A ES452786A ES452786A3 ES 452786 A3 ES452786 A3 ES 452786A3 ES 452786 A ES452786 A ES 452786A ES 452786 A ES452786 A ES 452786A ES 452786 A3 ES452786 A3 ES 452786A3
- Authority
- ES
- Spain
- Prior art keywords
- insulin
- metals
- crystals
- crystallization
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Abstract
A method for the production of insulin preparations with prolonged effect, consisting of suspending crystals of insulin in the form of rhombohedrons of defined edges limited by flat crystalline faces in an aqueous injectable medium which, if desired, contains metals that cause the crystallization of the insulin or substances, for example buffer substances, whose anions are combined with the promoter metals of the neutral reaction crystallization or which, if desired, contain said metals as well as said substances, whose process is characterized by using insulin crystals originating from bovine pancreatic glands, adjust the suspension to a ph of 6.5 to 7.5 and add ions of one or more crystallization promoting metals in a proportion such that the insulin crystals suspended at ph 7.0 contain a maximum of 0, 25 milliequival metal entities promoter of crystallization per gram of crystals. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES452786A ES452786A3 (en) | 1976-10-27 | 1976-10-27 | A procedure for the production of insulin preparations with a prolonged effect. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES452786A ES452786A3 (en) | 1976-10-27 | 1976-10-27 | A procedure for the production of insulin preparations with a prolonged effect. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES452786A3 true ES452786A3 (en) | 1977-10-16 |
Family
ID=8472484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES452786A Expired ES452786A3 (en) | 1976-10-27 | 1976-10-27 | A procedure for the production of insulin preparations with a prolonged effect. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES452786A3 (en) |
-
1976
- 1976-10-27 ES ES452786A patent/ES452786A3/en not_active Expired
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980202 |