IE40985B1 - Insulin preparations having antidiabetic activity and process for their manufacture - Google Patents

Insulin preparations having antidiabetic activity and process for their manufacture

Info

Publication number
IE40985B1
IE40985B1 IE832/75A IE83275A IE40985B1 IE 40985 B1 IE40985 B1 IE 40985B1 IE 832/75 A IE832/75 A IE 832/75A IE 83275 A IE83275 A IE 83275A IE 40985 B1 IE40985 B1 IE 40985B1
Authority
IE
Ireland
Prior art keywords
insulin
manufacture
insulin preparations
zinc ion
phenylalanine
Prior art date
Application number
IE832/75A
Other versions
IE40985L (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2418218A external-priority patent/DE2418218A1/en
Priority claimed from DE19742459515 external-priority patent/DE2459515C3/en
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IE40985L publication Critical patent/IE40985L/en
Publication of IE40985B1 publication Critical patent/IE40985B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

1492837 Sustained release insulin preparations HOECHST AG 7 April 1975 [13 April 1974 17 Dec 1974] 14079/75 Heading A5B Sustained release insulin preparations comprise (1) an aqueous medium, (2) a crystalline insulin, (3) dissolved des-phenylalanine <SP>B1</SP>-insulin of the same species and (4) 25 to 80 meg of zinc ion per 100 I.U. of insulin. The insulin and insulin derivative may be bovine or porcine. The zinc ion may be present as zinc chloride. The preparation may be made by mixing a suspension of insulin crystals containing zinc ion with a solution of des-phenylalanine-insulin also containing zinc ions and adjusting the pH to the required range. [GB1492837A]
IE832/75A 1974-04-13 1975-04-11 Insulin preparations having antidiabetic activity and process for their manufacture IE40985B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2418218A DE2418218A1 (en) 1974-04-13 1974-04-13 Long acting insulin compstns - contg. a crystalline insulin suspension and des phenyl alanine insulin soln.
DE19742459515 DE2459515C3 (en) 1974-12-17 1974-12-17 Medicinal preparations with an antidiabetic effect

Publications (2)

Publication Number Publication Date
IE40985L IE40985L (en) 1975-10-13
IE40985B1 true IE40985B1 (en) 1979-09-26

Family

ID=25766977

Family Applications (1)

Application Number Title Priority Date Filing Date
IE832/75A IE40985B1 (en) 1974-04-13 1975-04-11 Insulin preparations having antidiabetic activity and process for their manufacture

Country Status (11)

Country Link
AU (1) AU500430B2 (en)
CA (1) CA1047919A (en)
EG (1) EG12098A (en)
ES (1) ES436398A1 (en)
FI (1) FI751084A (en)
FR (1) FR2267116B1 (en)
GB (1) GB1492837A (en)
IE (1) IE40985B1 (en)
IL (1) IL47043A (en)
LU (1) LU72269A1 (en)
NL (1) NL7504165A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1560232A (en) * 1977-02-01 1980-01-30 Novo Industri As Biphasic insulin preparations comprising crystalline insulin and monodesamido insulin
DE3717370A1 (en) * 1987-05-22 1988-12-01 Hoechst Ag MIXED CRYSTALS FROM INSULIN AND INSULINE DERIVATIVES, METHOD FOR THE PRODUCTION OF THESE MIXED CRYSTALS, PHARMACEUTICAL AGENTS CONTAINING THESE MIXED CRYSTALS AND THEIR USE FOR TREATING DIABETES MELLITUS
WO1997005166A1 (en) 1995-07-25 1997-02-13 Novartis Ag Transforming growth factor beta crystals

Also Published As

Publication number Publication date
CA1047919A (en) 1979-02-06
AU8007375A (en) 1976-10-14
IL47043A0 (en) 1975-06-25
NL7504165A (en) 1975-10-15
IE40985L (en) 1975-10-13
FI751084A (en) 1975-10-14
FR2267116A1 (en) 1975-11-07
IL47043A (en) 1978-06-15
EG12098A (en) 1980-12-31
GB1492837A (en) 1977-11-23
ES436398A1 (en) 1977-05-01
AU500430B2 (en) 1979-05-24
FR2267116B1 (en) 1978-10-06
LU72269A1 (en) 1977-02-03

Similar Documents

Publication Publication Date Title
AU580355B2 (en) N-((4,6-dimethoxypyrimidin-2-YL)Aminocarbonyl)-3- trifluoromethylpridine-2-sulfonamide or salts thereof, herbicidal composition containing the same, and process for the production of the compound
EP0178665A3 (en) Stable erythropoietin preparation and process for formulating the same
ES8106564A1 (en) Electrolytic production of certain trichloropicolinic acids and/or 3,6-dichloropicolinic acid.
GB1495692A (en) Zinc sulphadiazine as a medicament
GB1323000A (en) Method of recovering proteins from microbial cells
AU7054087A (en) Process for preparing high-purity dermatan sulphate, and pharmaceutical compositions which contain it
AU587251B2 (en) 2,6-Bis(N-loweralkylcarbamoyl) pyridine-4-carboxylic acid derivatives
IE40985B1 (en) Insulin preparations having antidiabetic activity and process for their manufacture
EP0288907A3 (en) Method for inhibiting loss of cognitive functions employing an ace inhibitor
GB1533906A (en) Process for reducing the water sensitivity of polyvinyl alcohol
EP0158233A3 (en) Process for the manufacture of liquid, aqueous dyestuff preparations with a low salt content
GB1492530A (en) Process for keeping constant the activity of alkaline phosphatase
GB1499480A (en) Process for the manufacture of pure substituted 2,5-diarylaminoterephthalates and the corresponding free acids
EP0106448A3 (en) Process for the preparation of oxide materials, consisting of or containing tin oxide
AU539091B2 (en) Stabilized insulin crystal
GB1067253A (en) Process for the preparation of enzymes
IE38514B1 (en) Improvements in or relating to insulin preparations
AU5842186A (en) Process for the preparation of an aqueous solution of a heteropolysaccharide
EP0311999A3 (en) Method for producing calcium 5&#39;-ribonucleotide
ES424617A3 (en) A procedure for the preparation of insulinic preparations with a prolonged effect. (Machine-translation by Google Translate, not legally binding)
GB1464647A (en) Process for the preparation of choleragen
AU4591589A (en) Doxorubicin aqueous solutions
DE2112727A1 (en) Preservation of the neutral protease activity in alkaline protease containing enzyme mixtures using natural competitive protein substrates
JPS57171997A (en) Tetrocarcin and its preparation
GB1471178A (en) Process for preparing lead chromate pigment