GB1491390A - Production of an n-(substituted)piperazine compound - Google Patents
Production of an n-(substituted)piperazine compoundInfo
- Publication number
- GB1491390A GB1491390A GB19962/76A GB1996276A GB1491390A GB 1491390 A GB1491390 A GB 1491390A GB 19962/76 A GB19962/76 A GB 19962/76A GB 1996276 A GB1996276 A GB 1996276A GB 1491390 A GB1491390 A GB 1491390A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compound
- dialkanolamine
- cycloalkyl
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- GLUUGHFHXGJENI-UHFFFAOYSA-N diethylenediamine Natural products C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 1
- -1 piperazine compound Chemical class 0.000 title 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 150000005840 aryl radicals Chemical class 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000003018 phosphorus compounds Chemical class 0.000 abstract 2
- 150000004885 piperazines Chemical class 0.000 abstract 2
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 2
- 229940066771 systemic antihistamines piperazine derivative Drugs 0.000 abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000007791 liquid phase Substances 0.000 abstract 1
- OJMIONKXNSYLSR-UHFFFAOYSA-N phosphorous acid Chemical class OP(O)O OJMIONKXNSYLSR-UHFFFAOYSA-N 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/023—Preparation; Separation; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58300575A | 1975-06-02 | 1975-06-02 | |
| US58300675A | 1975-06-02 | 1975-06-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1491390A true GB1491390A (en) | 1977-11-09 |
Family
ID=27078704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB19962/76A Expired GB1491390A (en) | 1975-06-02 | 1976-05-14 | Production of an n-(substituted)piperazine compound |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS51149290A (enrdf_load_stackoverflow) |
| DE (1) | DE2624042A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2313369A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1491390A (enrdf_load_stackoverflow) |
| IT (1) | IT1063087B (enrdf_load_stackoverflow) |
| NL (1) | NL7605640A (enrdf_load_stackoverflow) |
| NO (1) | NO761856L (enrdf_load_stackoverflow) |
| SE (1) | SE7606174L (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4845218A (en) * | 1986-02-18 | 1989-07-04 | Basf Aktiengesellschaft | Preparation of n-methylpiperazine |
| US5110928A (en) * | 1990-03-15 | 1992-05-05 | Basf Aktiengesellschaft | Preparation of n-aryl-substituted 2-aminoalkyl-2-hydroxyalkylamines and n-aryl-substituted piperazines |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5742679A (en) * | 1980-08-29 | 1982-03-10 | Otsuka Pharmaceut Co Ltd | Preparation of phenylpiperazine derivative |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2636033A (en) | 1950-06-01 | 1953-04-21 | Colgate Palmolive Peet Co | Process for preparing n-n' dialkanol piperazine |
| DE1002359B (de) | 1954-01-30 | 1957-02-14 | Hoechst Ag | Verfahren zur Herstellung von N,N'-Dioxyaethylpiperazin |
| US2910477A (en) | 1956-10-18 | 1959-10-27 | Dow Chemical Co | Preparation of piperazine |
| US3869527A (en) | 1971-08-17 | 1975-03-04 | Leo Ab | Secondary phosphate esters |
| GB1424513A (en) | 1972-06-13 | 1976-02-11 | Ciba Geigy Ag | Organic phosphates |
-
1976
- 1976-05-14 GB GB19962/76A patent/GB1491390A/en not_active Expired
- 1976-05-26 NL NL7605640A patent/NL7605640A/xx not_active Application Discontinuation
- 1976-05-28 DE DE19762624042 patent/DE2624042A1/de active Pending
- 1976-05-31 FR FR7616316A patent/FR2313369A1/fr active Granted
- 1976-06-01 JP JP51062987A patent/JPS51149290A/ja active Pending
- 1976-06-01 NO NO761856A patent/NO761856L/no unknown
- 1976-06-01 SE SE7606174*7A patent/SE7606174L/xx unknown
- 1976-06-01 IT IT23850/76A patent/IT1063087B/it active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4845218A (en) * | 1986-02-18 | 1989-07-04 | Basf Aktiengesellschaft | Preparation of n-methylpiperazine |
| US5110928A (en) * | 1990-03-15 | 1992-05-05 | Basf Aktiengesellschaft | Preparation of n-aryl-substituted 2-aminoalkyl-2-hydroxyalkylamines and n-aryl-substituted piperazines |
Also Published As
| Publication number | Publication date |
|---|---|
| SE7606174L (sv) | 1976-12-03 |
| NL7605640A (nl) | 1976-12-06 |
| NO761856L (enrdf_load_stackoverflow) | 1976-12-03 |
| DE2624042A1 (de) | 1976-12-23 |
| FR2313369A1 (fr) | 1976-12-31 |
| IT1063087B (it) | 1985-02-11 |
| FR2313369B3 (enrdf_load_stackoverflow) | 1979-02-16 |
| JPS51149290A (en) | 1976-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |