GB1494886A - Method of producing morpholine compounds - Google Patents

Method of producing morpholine compounds

Info

Publication number
GB1494886A
GB1494886A GB2080776A GB2080776A GB1494886A GB 1494886 A GB1494886 A GB 1494886A GB 2080776 A GB2080776 A GB 2080776A GB 2080776 A GB2080776 A GB 2080776A GB 1494886 A GB1494886 A GB 1494886A
Authority
GB
United Kingdom
Prior art keywords
alkyl
formula
aryl
phosphorus compound
phosphoric acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2080776A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Texaco Development Corp
Original Assignee
Texaco Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Texaco Development Corp filed Critical Texaco Development Corp
Publication of GB1494886A publication Critical patent/GB1494886A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/023—Preparation; Separation; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Abstract

1494886 Morpholine derivatives TEXACO DEVELOPMENT CORP 20 May 1976 [2 June 1975 (2)] 20807/76 Heading C2C A process for the production of a morpholine derivative of the formula wherein R<SP>1</SP>, R<SP>2</SP>and R<SP>3</SP> are independently hydrogen or alkyl, and R<SP>4</SP> is hydrogen or an optionally substituted alkyl, cycloalkyl, saturated heterocyclic or aryl radical, comprises contacting a glycol of the formula with ammonia or an amine of the formula R<SP>4</SP>.NH 2 in the presence of a phosphorus compound at a temperature of from 220‹ to 350‹ C. under a pressure sufficient to maintain the reactants in the liquid phase. The phosphorus compound is suitably an acidic metal phosphate, a phosphoric or phosphorous acid or anhydride, an alkyl or aryl phosphate or phosphite ester, an alkyl- or aryl-substituted phosphorous or phosphoric acid, an alkali metal salt of phosphoric acid, a thioanalogue of the foregoing, or a mixture thereof.
GB2080776A 1975-06-02 1976-05-20 Method of producing morpholine compounds Expired GB1494886A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58300475A 1975-06-02 1975-06-02
US58302475A 1975-06-02 1975-06-02

Publications (1)

Publication Number Publication Date
GB1494886A true GB1494886A (en) 1977-12-14

Family

ID=27078703

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2080776A Expired GB1494886A (en) 1975-06-02 1976-05-20 Method of producing morpholine compounds

Country Status (6)

Country Link
JP (1) JPS51149286A (en)
DE (1) DE2624043A1 (en)
FR (1) FR2313374A1 (en)
GB (1) GB1494886A (en)
IT (1) IT1063420B (en)
NL (1) NL7605641A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405784A (en) 1981-06-29 1983-09-20 Air Products And Chemicals, Inc. Method of making triethylenediamine
US4514567A (en) * 1981-06-29 1985-04-30 Air Products And Chemicals, Inc. Process for preparing triethylenediamine

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1530570A (en) * 1977-09-30 1978-11-01 Texaco Development Corp Process for the simultaneous production of 2-(2-aminoalkoxy)alkanol and morpholine
SE439011B (en) * 1980-03-21 1985-05-28 Ferrosan Ab MORPHOLINO SOCIETIES, COMPOSITIONS CONTAINING THESE AND USE THEREOF

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR804193A (en) * 1934-07-12 1936-10-17 Carbide & Carbon Chem Corp Morpholine manufacturing process
US3154544A (en) * 1956-05-02 1964-10-27 Wyandotte Chemicals Corp Substituted morpholines
US3151112A (en) * 1956-05-21 1964-09-29 Jefferson Chem Co Inc Process for the preparation of morpholines

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405784A (en) 1981-06-29 1983-09-20 Air Products And Chemicals, Inc. Method of making triethylenediamine
US4514567A (en) * 1981-06-29 1985-04-30 Air Products And Chemicals, Inc. Process for preparing triethylenediamine

Also Published As

Publication number Publication date
DE2624043A1 (en) 1976-12-23
JPS5335951B2 (en) 1978-09-29
FR2313374B1 (en) 1980-08-01
IT1063420B (en) 1985-02-11
FR2313374A1 (en) 1976-12-31
AU1444176A (en) 1977-12-08
NL7605641A (en) 1976-12-06
JPS51149286A (en) 1976-12-22

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee