ES401525A1 - A procedure for the production of an antibiotic substance. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the production of an antibiotic substance. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES401525A1 ES401525A1 ES401525A ES401525A ES401525A1 ES 401525 A1 ES401525 A1 ES 401525A1 ES 401525 A ES401525 A ES 401525A ES 401525 A ES401525 A ES 401525A ES 401525 A1 ES401525 A1 ES 401525A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- aryloxy
- aryl
- alkyl
- following general
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Abstract
A procedure for the production of an antibiotic substance of the following general formula: **(See formula)** where Y represents (see formula) R represents a hydrogen atom, a halogen atom or an azido, acyloxy, alkoxy, aryloxy or SR'group (R' represents an alkyl, aryl or heterocyclic group), each of the radicals R1 and R2 represents a hydrogen atom or an alkyl, aryl, aralkyl, aryloxy, cycloalkane or heterocyclic group with or without substituents or R1 and R2 can form a ring together; R3 represents a hydrogen atom, a halogen atom or a hydroxyl, amino, alkylamino, azido, cyano, alkyloxy, alkylthio, aryloxycarbonyl, aralkyloxycarbonyl or alkoxycarbonyl group and n represents the integer 0 or 1; whose procedure consists in reacting the salts of 6-aminopenicilánica acid or 7-aminocefalosporónicos acids of the following general formula: **(See formula)** where the symbol Y has the meaning given above, with trivalent phosphorus compounds of the following general formula: **(See formula)** where R4 represents an alkyl, haloalkyl, aryl, aralkyl, alkyloxy, haloalkyloxy, aryloxy, aralkyloxy or dialkylamino group; R5 represents an alkyl, haloalkyl, aryl, aralkyl, alkyloxy, aryloxy, haloalkyloxy, aralkyloxy or dialkylamino group or a halogen atom or R4 and R5 can form a ring and X represents a halogen atom, reacting the product thus obtained with reactive derivatives of carboxylic acids of the following general formula: **(See formula)** where R1, R2, R3 and n have the meaning described above and then solvolize the product to remove the protecting group. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2414171A JPS5231879B1 (en) | 1971-04-15 | 1971-04-15 | |
| JP2414071A JPS531278B1 (en) | 1971-04-15 | 1971-04-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES401525A1 true ES401525A1 (en) | 1975-09-01 |
Family
ID=26361623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES401525A Expired ES401525A1 (en) | 1971-04-15 | 1972-04-06 | A procedure for the production of an antibiotic substance. (Machine-translation by Google Translate, not legally binding) |
Country Status (19)
| Country | Link |
|---|---|
| AR (2) | AR201419A1 (en) |
| AT (1) | AT320849B (en) |
| BE (1) | BE781934A (en) |
| BR (1) | BR7202225D0 (en) |
| CA (1) | CA1041996A (en) |
| CH (1) | CH547309A (en) |
| CS (1) | CS178106B2 (en) |
| DD (1) | DD97422A5 (en) |
| DE (1) | DE2218209C3 (en) |
| DK (1) | DK142418B (en) |
| ES (1) | ES401525A1 (en) |
| FR (1) | FR2133686A1 (en) |
| HU (1) | HU166324B (en) |
| IE (1) | IE36288B1 (en) |
| IL (1) | IL39062A (en) |
| NL (1) | NL158803B (en) |
| NO (1) | NO146986C (en) |
| PH (1) | PH12645A (en) |
| SE (1) | SE392275C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE791099A (en) * | 1971-11-09 | 1973-05-08 | American Home Prod | INTERMEDIARIES FOR THE PRODUCTION OF SEMI-SYNTHETIC PENICILLINS AND METHODS FOR OBTAINING THEM |
| GB1459999A (en) * | 1972-12-27 | 1976-12-31 | Novo Industri As | Penicillin and cephalosporin intermediates |
| GB2161476B (en) | 1984-05-25 | 1988-01-27 | Toyama Chemical Co Ltd | 2-aminothiazolyl-2-methoxyimino acetamides and their use in preparing cephalosporins |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE34822B1 (en) * | 1969-12-26 | 1975-08-20 | Univ Osaka | Process for producing 6-amino penicillanic acid |
-
1972
- 1972-03-23 IL IL39062A patent/IL39062A/en unknown
- 1972-03-29 SE SE7204191A patent/SE392275C/en unknown
- 1972-04-06 ES ES401525A patent/ES401525A1/en not_active Expired
- 1972-04-11 BE BE781934A patent/BE781934A/en not_active IP Right Cessation
- 1972-04-13 IE IE487/72A patent/IE36288B1/en unknown
- 1972-04-13 HU HUTO874A patent/HU166324B/hu unknown
- 1972-04-13 FR FR7212995A patent/FR2133686A1/en active Granted
- 1972-04-14 DK DK181972AA patent/DK142418B/en not_active IP Right Cessation
- 1972-04-14 DD DD162300A patent/DD97422A5/xx unknown
- 1972-04-14 BR BR2225/72A patent/BR7202225D0/en unknown
- 1972-04-14 NL NL7205083.A patent/NL158803B/en not_active IP Right Cessation
- 1972-04-14 DE DE2218209A patent/DE2218209C3/en not_active Expired
- 1972-04-14 NO NO1299/72A patent/NO146986C/en unknown
- 1972-04-14 AT AT329272A patent/AT320849B/en not_active IP Right Cessation
- 1972-04-14 AR AR241483D patent/AR201419A1/en active
- 1972-04-14 CH CH553872A patent/CH547309A/en not_active IP Right Cessation
- 1972-04-14 CS CS2553A patent/CS178106B2/cs unknown
- 1972-04-17 PH PH13455A patent/PH12645A/en unknown
- 1972-04-17 CA CA139,833A patent/CA1041996A/en not_active Expired
-
1973
- 1973-01-01 AR AR246043A patent/AR204077A1/en active
Also Published As
| Publication number | Publication date |
|---|---|
| AR204077A1 (en) | 1975-11-20 |
| IE36288L (en) | 1972-10-15 |
| SE392275B (en) | 1977-03-21 |
| FR2133686A1 (en) | 1972-12-01 |
| NL7205083A (en) | 1972-10-17 |
| DE2218209C3 (en) | 1980-10-16 |
| IE36288B1 (en) | 1976-09-29 |
| AT320849B (en) | 1975-02-25 |
| CS178106B2 (en) | 1977-08-31 |
| FR2133686B1 (en) | 1975-12-26 |
| BR7202225D0 (en) | 1973-07-17 |
| NO146986B (en) | 1982-10-04 |
| DE2218209A1 (en) | 1972-10-26 |
| PH12645A (en) | 1979-07-11 |
| DK142418B (en) | 1980-10-27 |
| CA1041996A (en) | 1978-11-07 |
| DD97422A5 (en) | 1973-05-05 |
| SE392275C (en) | 1983-11-28 |
| AR201419A1 (en) | 1975-03-14 |
| NO146986C (en) | 1983-01-12 |
| DK142418C (en) | 1982-12-06 |
| CH547309A (en) | 1974-03-29 |
| BE781934A (en) | 1972-10-11 |
| IL39062A (en) | 1975-02-10 |
| IL39062A0 (en) | 1972-05-30 |
| NL158803B (en) | 1978-12-15 |
| HU166324B (en) | 1975-02-28 |
| DE2218209B2 (en) | 1980-02-28 |
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