ES422873A1 - Method for the production of derivatives of 6-aminopenicillanic acid - Google Patents
Method for the production of derivatives of 6-aminopenicillanic acidInfo
- Publication number
- ES422873A1 ES422873A1 ES422873A ES422873A ES422873A1 ES 422873 A1 ES422873 A1 ES 422873A1 ES 422873 A ES422873 A ES 422873A ES 422873 A ES422873 A ES 422873A ES 422873 A1 ES422873 A1 ES 422873A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- represent
- derivatives
- formula
- ring system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
A method for producing 6-aminopenicillanic acid derivatives and their pharmaceutically acceptable non-toxic salts, the derivatives of which respond to the general formula: ** (See formula) ** wherein R1, R2 and R3 represent the same or different substituents and each represents an unsubstituted or substituted aliphatic hydrocarbon radical, a monocyclic or bicyclic carbocyclic aryl radical, an aralkyl radical, a cycloalkyl radical, a cycloalkylalkyl radical, a heterocyclic radical, or a heterocyclic substituted alkyl radical; R3 can also represent hydrogen; R1 and R2, together with the nitrogen atom, represent a ring system; R1 and R3 together with the N-C atoms represent a ring system; characterized in that a reactive derivative of a compound of formula II is reacted; ** (See formula) ** where R1, R2 and R3 have the same meanings defined above, and R5 represents O or S, with a 6-aminopenicilanic acid salt, preferably a salt with a strong tertiary amine, in an appropriate solvent and at a temperature that is at or below room temperature. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB541473A GB1417099A (en) | 1973-02-02 | 1973-02-02 | Method for the production of derivatives of 6-aminopenicillanic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES422873A1 true ES422873A1 (en) | 1976-05-01 |
Family
ID=9795736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES422873A Expired ES422873A1 (en) | 1973-02-02 | 1974-02-02 | Method for the production of derivatives of 6-aminopenicillanic acid |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS6037117B2 (en) |
| AR (1) | AR202703A1 (en) |
| AT (1) | AT329178B (en) |
| AU (1) | AU475538B2 (en) |
| BG (1) | BG21033A3 (en) |
| CA (1) | CA1014549A (en) |
| CH (1) | CH593979A5 (en) |
| CS (1) | CS182807B2 (en) |
| DD (1) | DD109636A5 (en) |
| DE (1) | DE2404587C2 (en) |
| DK (1) | DK141754B (en) |
| ES (1) | ES422873A1 (en) |
| FI (1) | FI60017C (en) |
| GB (1) | GB1417099A (en) |
| HU (1) | HU167788B (en) |
| NL (1) | NL7400972A (en) |
| NO (1) | NO147565C (en) |
| PL (1) | PL88593B1 (en) |
| SE (1) | SE412392B (en) |
| SU (1) | SU553935A3 (en) |
| YU (1) | YU39649B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU566843A1 (en) * | 1975-01-06 | 1977-07-30 | Ордена Трудового Красного Знамени Институт Органической Синтеза Ан Латвийской Сср | Method of preparing derivatives of 6- -amidino penicillanic acid |
| LU77362A1 (en) * | 1977-05-17 | 1979-01-19 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1293590A (en) * | 1969-11-11 | 1972-10-18 | Leo Pharm Prod Ltd | New penicillanic acid derivatives |
| BE758782A (en) * | 1969-11-11 | 1971-05-10 | Leo Pharm Prod Ltd | NEW DERIVATIVES OF 6-AMIDINO PENICILLANIC ACID, THEIR PREPARATION PROCESS AND THEIR APPLICATIONS AS ANTIBIOTICS |
| GB1315566A (en) * | 1970-11-06 | 1973-05-02 | Leo Pharm Prod Ltd | Penicillanic acid derivatives |
-
1973
- 1973-02-02 GB GB541473A patent/GB1417099A/en not_active Expired
-
1974
- 1974-01-16 AT AT33074*#A patent/AT329178B/en not_active IP Right Cessation
- 1974-01-22 AR AR252017A patent/AR202703A1/en active
- 1974-01-24 NL NL7400972A patent/NL7400972A/xx not_active Application Discontinuation
- 1974-01-25 HU HULE732A patent/HU167788B/hu not_active IP Right Cessation
- 1974-01-28 CS CS7400000539A patent/CS182807B2/en unknown
- 1974-01-28 FI FI224/74A patent/FI60017C/en active
- 1974-01-29 YU YU203/74A patent/YU39649B/en unknown
- 1974-01-29 CA CA191,180A patent/CA1014549A/en not_active Expired
- 1974-01-29 DK DK44474AA patent/DK141754B/en not_active IP Right Cessation
- 1974-01-31 PL PL1974168467A patent/PL88593B1/pl unknown
- 1974-01-31 DD DD176296A patent/DD109636A5/xx unknown
- 1974-01-31 AU AU65055/74A patent/AU475538B2/en not_active Expired
- 1974-01-31 DE DE2404587A patent/DE2404587C2/en not_active Expired
- 1974-02-01 NO NO740341A patent/NO147565C/en unknown
- 1974-02-01 BG BG025676A patent/BG21033A3/en unknown
- 1974-02-01 JP JP49012889A patent/JPS6037117B2/en not_active Expired
- 1974-02-01 CH CH143674A patent/CH593979A5/xx not_active IP Right Cessation
- 1974-02-01 SU SU1993873A patent/SU553935A3/en active
- 1974-02-01 SE SE7401380A patent/SE412392B/en not_active IP Right Cessation
- 1974-02-02 ES ES422873A patent/ES422873A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| HU167788B (en) | 1975-12-25 |
| FI60017C (en) | 1981-11-10 |
| CH593979A5 (en) | 1977-12-30 |
| JPS49102690A (en) | 1974-09-27 |
| AU475538B2 (en) | 1976-08-26 |
| FI60017B (en) | 1981-07-31 |
| DE2404587C2 (en) | 1982-12-23 |
| DD109636A5 (en) | 1974-11-12 |
| GB1417099A (en) | 1975-12-10 |
| AU6505574A (en) | 1975-07-31 |
| NO740341L (en) | 1974-08-05 |
| AR202703A1 (en) | 1975-07-15 |
| DE2404587A1 (en) | 1974-08-15 |
| AT329178B (en) | 1976-04-26 |
| YU39649B (en) | 1985-03-20 |
| NO147565B (en) | 1983-01-24 |
| DK141754C (en) | 1980-11-03 |
| YU20374A (en) | 1982-02-28 |
| SE412392B (en) | 1980-03-03 |
| NO147565C (en) | 1983-05-04 |
| CA1014549A (en) | 1977-07-26 |
| NL7400972A (en) | 1974-08-06 |
| JPS6037117B2 (en) | 1985-08-24 |
| ATA33074A (en) | 1975-07-15 |
| SU553935A3 (en) | 1977-04-05 |
| CS182807B2 (en) | 1978-05-31 |
| BG21033A3 (en) | 1976-01-20 |
| DK141754B (en) | 1980-06-09 |
| PL88593B1 (en) | 1976-09-30 |
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