GB1495197A - Process for preparing pyridoxin derivatives - Google Patents
Process for preparing pyridoxin derivativesInfo
- Publication number
- GB1495197A GB1495197A GB46094/75A GB4609475A GB1495197A GB 1495197 A GB1495197 A GB 1495197A GB 46094/75 A GB46094/75 A GB 46094/75A GB 4609475 A GB4609475 A GB 4609475A GB 1495197 A GB1495197 A GB 1495197A
- Authority
- GB
- United Kingdom
- Prior art keywords
- aminobenzoate
- ethyl
- amino
- derivatives
- propyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
- C07D213/67—2-Methyl-3-hydroxy-4,5-bis(hydroxy-methyl)pyridine, i.e. pyridoxine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
1495197 Pyridoxin derivatives LAMBELETTI ESPANA SA 6 Nov 1975 [6 Nov 1974] 46094/75 Heading C2V Pyridoxin derivatives have the formula where Y is n is 2 or 3 and R<SP>1</SP> and R<SP>2</SP> are alkyl or cycloalkyl radicals or R<SP>1</SP> and R<SP>2</SP> together with the nitrogen atom form a heterocyclic ring. The derivatives may be in the form of non-toxic salts with organic and inorganic acids. The derivatives are obtained by reacting basic esters of p-aminobenzoic acid with pyridoxal by elimination of water. In examples pyridoxal hydrochloride is reacted with diethyl-amino-ethyl p-aminobenzoate, with di-n-butyl-amino-propyl-p-aminobenzoate, with di-iso-propyl-amino-ethyl paminobenzoate, with diethyl-amino-propyl paminobenzoate, with di-n-butyl-amino-ethyl paminobenzoate, with pyrrolidin-ethyl p-aminobenzoate, with morpholin-ethyl p-aminobenzoate, with di-iso-butyl-amino-ethyl p-aminobenzoate, with piperidin-propyl p-aminobenzoate, with piperidin-ethyl p-aminobenzoate and with di-methyl-amino-propyl p-aminobenzoate. The derivatives are mixed with pharmaceutically acceptable carriers.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES431712A ES431712A1 (en) | 1974-11-06 | 1974-11-06 | Process for preparing pyridoxin derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1495197A true GB1495197A (en) | 1977-12-14 |
Family
ID=8467910
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB46094/75A Expired GB1495197A (en) | 1974-11-06 | 1975-11-06 | Process for preparing pyridoxin derivatives |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS51125289A (en) |
DE (1) | DE2549863C3 (en) |
ES (1) | ES431712A1 (en) |
FR (1) | FR2290201A1 (en) |
GB (1) | GB1495197A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4233304A (en) * | 1978-07-31 | 1980-11-11 | Crinos Industria Farmacobiologica S.P.A. | Pyridoxine derivatives |
-
1974
- 1974-11-06 ES ES431712A patent/ES431712A1/en not_active Expired
-
1975
- 1975-11-06 JP JP50133926A patent/JPS51125289A/en active Pending
- 1975-11-06 GB GB46094/75A patent/GB1495197A/en not_active Expired
- 1975-11-06 DE DE2549863A patent/DE2549863C3/en not_active Expired
- 1975-11-06 FR FR7533979A patent/FR2290201A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
DE2549863C3 (en) | 1980-01-03 |
DE2549863A1 (en) | 1976-09-23 |
FR2290201A1 (en) | 1976-06-04 |
ES431712A1 (en) | 1976-11-16 |
DE2549863B2 (en) | 1979-05-03 |
JPS51125289A (en) | 1976-11-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |