GB1490671A - Perhalo-alkylamidines - Google Patents

Perhalo-alkylamidines

Info

Publication number
GB1490671A
GB1490671A GB1016/76A GB101676A GB1490671A GB 1490671 A GB1490671 A GB 1490671A GB 1016/76 A GB1016/76 A GB 1016/76A GB 101676 A GB101676 A GB 101676A GB 1490671 A GB1490671 A GB 1490671A
Authority
GB
United Kingdom
Prior art keywords
alkyl
prepared
phenyl
substituted
nitrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1016/76A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1490671A publication Critical patent/GB1490671A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827—X being H
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
GB1016/76A 1975-01-15 1976-01-12 Perhalo-alkylamidines Expired GB1490671A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54130875A 1975-01-15 1975-01-15
US62973575A 1975-11-10 1975-11-10

Publications (1)

Publication Number Publication Date
GB1490671A true GB1490671A (en) 1977-11-02

Family

ID=27066677

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1016/76A Expired GB1490671A (en) 1975-01-15 1976-01-12 Perhalo-alkylamidines

Country Status (21)

Country Link
JP (1) JPS51125202A (cs)
AR (1) AR213168A1 (cs)
AU (1) AU499649B2 (cs)
BG (1) BG25074A3 (cs)
CS (1) CS189737B2 (cs)
DD (1) DD124598A5 (cs)
DE (1) DE2601137A1 (cs)
DK (1) DK593975A (cs)
ES (1) ES444259A1 (cs)
FI (1) FI753673A7 (cs)
FR (1) FR2297615A1 (cs)
GB (1) GB1490671A (cs)
IL (1) IL48784A0 (cs)
LU (1) LU74170A1 (cs)
NL (1) NL7515256A (cs)
NO (1) NO754426L (cs)
NZ (1) NZ179730A (cs)
PL (1) PL101099B1 (cs)
PT (1) PT64673B (cs)
SE (1) SE7514776L (cs)
SU (1) SU633471A3 (cs)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423246A (en) 1982-02-22 1983-12-27 Olin Corporation Selected trichloroacetamidines
EP1586561A1 (en) * 2004-04-13 2005-10-19 Cephalon, Inc. Bicyclic aromatic sulfinyl derivatives
WO2005100311A1 (en) * 2004-04-13 2005-10-27 Cephalon, Inc. Bicyclic aromatic sulfinyl derivatives
WO2008144263A1 (en) * 2007-05-18 2008-11-27 The Ohio State University Research Foundation Potent indole-3-carbinol-derived antitumor agents
US8153680B2 (en) 2009-08-25 2012-04-10 The Ohio State University Research Foundation Alkyl indole-3-carbinol-derived antitumor agents
EP2754690A1 (en) * 2007-05-10 2014-07-16 Constar International LLC Oxygen scavenging molecules, articles containing same, and methods of their use
US9222020B2 (en) 2009-11-13 2015-12-29 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
US9896554B2 (en) 2009-09-29 2018-02-20 Plastipak Packaging, Inc. Colorant compatible oxygen scavenging polymer compositions and articles made from same
US10040922B2 (en) 2009-11-13 2018-08-07 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
US10351692B2 (en) 2014-10-17 2019-07-16 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
US11338983B2 (en) 2014-08-22 2022-05-24 Plastipak Packaging, Inc. Oxygen scavenging compositions, articles containing same, and methods of their use
US11649339B2 (en) 2012-04-30 2023-05-16 Plastipak Packaging, Inc. Oxygen scavenging compositions, articles containing same, and methods of their use
CN117756628A (zh) * 2023-12-29 2024-03-26 江苏兄弟维生素有限公司 利用氨基嘧啶母液游离盐酸乙脒并联产甲酸甲酯的方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4709052A (en) * 1983-05-31 1987-11-24 Sumitomo Chemical Company, Limited Soil disease-controlling imides
EP0226511B1 (fr) * 1985-12-13 1989-08-02 LABORATOIRE L. LAFON Société anonyme dite: Dérivés de 5-phényl-1,4,5,6-tétrahydropyrimidine, procédé de préparation et utilisation en thérapeutique
CA2089261A1 (en) * 1990-08-30 1992-03-01 John F.W. Keana Substituted amidines having high binding to the sigma receptor and the use thereof
ES2055651B1 (es) * 1992-07-20 1995-03-01 Vita Invest Sa Procedimiento para la obtencion de nuevas amidinas derivadas de 3-aminoetilindoles.
GB9425701D0 (en) 1994-12-20 1995-02-22 Wellcome Found Enzyme inhibitors

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423246A (en) 1982-02-22 1983-12-27 Olin Corporation Selected trichloroacetamidines
AU2005233197B2 (en) * 2004-04-13 2012-04-26 Cephalon, Inc. Bicyclic aromatic sulfinyl derivatives
EP1586561A1 (en) * 2004-04-13 2005-10-19 Cephalon, Inc. Bicyclic aromatic sulfinyl derivatives
WO2005100311A1 (en) * 2004-04-13 2005-10-27 Cephalon, Inc. Bicyclic aromatic sulfinyl derivatives
US7423176B2 (en) 2004-04-13 2008-09-09 Cephalon, Inc. Bicyclic aromatic sulfinyl derivatives
US8314155B2 (en) 2004-04-13 2012-11-20 Cephalon, Inc Bicyclic aromatic sulfinyl derivatives
EP2754690A1 (en) * 2007-05-10 2014-07-16 Constar International LLC Oxygen scavenging molecules, articles containing same, and methods of their use
US10125096B2 (en) 2007-05-10 2018-11-13 Plastipak Packaging, Inc. Oxygen scavenging molecules, articles containing same, and methods of their use
US11739059B2 (en) 2007-05-10 2023-08-29 Plastipak Packaging, Inc. Oxygen scavenging molecules, articles containing same, and methods of their use
US10906870B2 (en) 2007-05-10 2021-02-02 Plastipak Packaging, Inc. Oxygen scavenging molecules, articles containing same, and methods of their use
US7807705B2 (en) 2007-05-18 2010-10-05 The Ohio State University Research Foundation Potent indole-3-carbinol-derived antitumor agents
WO2008144263A1 (en) * 2007-05-18 2008-11-27 The Ohio State University Research Foundation Potent indole-3-carbinol-derived antitumor agents
US8153680B2 (en) 2009-08-25 2012-04-10 The Ohio State University Research Foundation Alkyl indole-3-carbinol-derived antitumor agents
US9896554B2 (en) 2009-09-29 2018-02-20 Plastipak Packaging, Inc. Colorant compatible oxygen scavenging polymer compositions and articles made from same
US10040922B2 (en) 2009-11-13 2018-08-07 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
US10059666B2 (en) 2009-11-13 2018-08-28 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
US9222020B2 (en) 2009-11-13 2015-12-29 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
US11649339B2 (en) 2012-04-30 2023-05-16 Plastipak Packaging, Inc. Oxygen scavenging compositions, articles containing same, and methods of their use
US11338983B2 (en) 2014-08-22 2022-05-24 Plastipak Packaging, Inc. Oxygen scavenging compositions, articles containing same, and methods of their use
US11345534B2 (en) 2014-08-22 2022-05-31 Plastipak Packaging, Inc. Oxygen scavenging compositions, articles containing same, and methods of their use
US10351692B2 (en) 2014-10-17 2019-07-16 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
US11066536B2 (en) 2014-10-17 2021-07-20 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
US11753524B2 (en) 2014-10-17 2023-09-12 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
CN117756628A (zh) * 2023-12-29 2024-03-26 江苏兄弟维生素有限公司 利用氨基嘧啶母液游离盐酸乙脒并联产甲酸甲酯的方法

Also Published As

Publication number Publication date
NL7515256A (nl) 1976-07-19
CS189737B2 (en) 1979-04-30
LU74170A1 (cs) 1976-12-31
PT64673B (fr) 1978-01-04
DE2601137A1 (de) 1976-07-22
ES444259A1 (es) 1977-10-01
AR213168A1 (es) 1978-12-29
NO754426L (cs) 1976-07-16
JPS51125202A (en) 1976-11-01
DD124598A5 (cs) 1977-03-02
BG25074A3 (bg) 1978-07-12
SU633471A3 (ru) 1978-11-15
AU499649B2 (en) 1979-04-26
NZ179730A (en) 1978-07-10
DK593975A (da) 1976-07-16
SE7514776L (sv) 1976-07-16
PT64673A (fr) 1976-02-01
PL101099B1 (pl) 1978-11-30
FR2297615A1 (fr) 1976-08-13
IL48784A0 (en) 1976-03-31
AU1006076A (en) 1977-07-14
FI753673A7 (cs) 1976-07-16

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee