JPS51125202A - Novel substituted perhaloalkylamidines as cardiac agent - Google Patents

Novel substituted perhaloalkylamidines as cardiac agent

Info

Publication number
JPS51125202A
JPS51125202A JP51002897A JP289776A JPS51125202A JP S51125202 A JPS51125202 A JP S51125202A JP 51002897 A JP51002897 A JP 51002897A JP 289776 A JP289776 A JP 289776A JP S51125202 A JPS51125202 A JP S51125202A
Authority
JP
Japan
Prior art keywords
perhaloalkylamidines
novel substituted
cardiac agent
cardiac
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP51002897A
Other languages
Japanese (ja)
Inventor
Esu Saari Uorufuretsudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS51125202A publication Critical patent/JPS51125202A/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827X being H
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/42Oxygen atoms attached in position 3 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
JP51002897A 1975-01-15 1976-01-14 Novel substituted perhaloalkylamidines as cardiac agent Pending JPS51125202A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54130875A 1975-01-15 1975-01-15
US62973575A 1975-11-10 1975-11-10

Publications (1)

Publication Number Publication Date
JPS51125202A true JPS51125202A (en) 1976-11-01

Family

ID=27066677

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51002897A Pending JPS51125202A (en) 1975-01-15 1976-01-14 Novel substituted perhaloalkylamidines as cardiac agent

Country Status (21)

Country Link
JP (1) JPS51125202A (en)
AR (1) AR213168A1 (en)
AU (1) AU499649B2 (en)
BG (1) BG25074A3 (en)
CS (1) CS189737B2 (en)
DD (1) DD124598A5 (en)
DE (1) DE2601137A1 (en)
DK (1) DK593975A (en)
ES (1) ES444259A1 (en)
FI (1) FI753673A (en)
FR (1) FR2297615A1 (en)
GB (1) GB1490671A (en)
IL (1) IL48784A0 (en)
LU (1) LU74170A1 (en)
NL (1) NL7515256A (en)
NO (1) NO754426L (en)
NZ (1) NZ179730A (en)
PL (1) PL101099B1 (en)
PT (1) PT64673B (en)
SE (1) SE7514776L (en)
SU (1) SU633471A3 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007532678A (en) * 2004-04-13 2007-11-15 セフアロン・インコーポレーテツド Bicyclic aromatic sulfinyl derivatives

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423246A (en) 1982-02-22 1983-12-27 Olin Corporation Selected trichloroacetamidines
US4709052A (en) * 1983-05-31 1987-11-24 Sumitomo Chemical Company, Limited Soil disease-controlling imides
ES2010668B3 (en) * 1985-12-13 1989-12-01 Laboratoire L Lafon Soc Anonyme Dite: PROCEDURE FOR THE PREPARATION OF 5-PHENYL-1,4,5,6-TETRAHYDROPYRIMIDINE DERIVATIVES.
WO1992004054A1 (en) * 1990-08-30 1992-03-19 STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALTH SCIENCES UNIVERSITY, PORTLAND, OREGON, and THE UNIVERSITY OF OREGON, EUGENE, OREGON, Johnson Hall, University of Oregon Substituted amidines having high binding to the sigma receptor and the use thereof
ES2055651B1 (en) * 1992-07-20 1995-03-01 Vita Invest Sa PROCEDURE FOR THE OBTAINING OF NEW AMIDINES DERIVED FROM 3-AMINOETILINDOLES.
GB9425701D0 (en) * 1994-12-20 1995-02-22 Wellcome Found Enzyme inhibitors
EP1586561A1 (en) * 2004-04-13 2005-10-19 Cephalon, Inc. Bicyclic aromatic sulfinyl derivatives
ES2456335T3 (en) * 2007-05-10 2014-04-22 Constar International Llc Oxygen capture molecules, articles that contain them and their methods of use
US7807705B2 (en) 2007-05-18 2010-10-05 The Ohio State University Research Foundation Potent indole-3-carbinol-derived antitumor agents
US8153680B2 (en) 2009-08-25 2012-04-10 The Ohio State University Research Foundation Alkyl indole-3-carbinol-derived antitumor agents
PL2483342T3 (en) 2009-09-29 2017-08-31 Plastipak Packaging, Inc. Colorant compatible oxygen scavenging polymer compositions and articles made from same
AU2010319298B2 (en) 2009-11-13 2015-11-05 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
WO2011060297A2 (en) 2009-11-13 2011-05-19 Constar International, Inc. Oxygen scavengers, composition comprising the scavengers, and articles made from the compositions
RU2640536C2 (en) 2012-04-30 2018-01-09 Пластипэк Пэкэджинг Инк. Oxygen absorbing compositions
US11338983B2 (en) 2014-08-22 2022-05-24 Plastipak Packaging, Inc. Oxygen scavenging compositions, articles containing same, and methods of their use
US10351692B2 (en) 2014-10-17 2019-07-16 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007532678A (en) * 2004-04-13 2007-11-15 セフアロン・インコーポレーテツド Bicyclic aromatic sulfinyl derivatives

Also Published As

Publication number Publication date
AU499649B2 (en) 1979-04-26
NO754426L (en) 1976-07-16
CS189737B2 (en) 1979-04-30
NZ179730A (en) 1978-07-10
FI753673A (en) 1976-07-16
IL48784A0 (en) 1976-03-31
NL7515256A (en) 1976-07-19
PT64673B (en) 1978-01-04
PT64673A (en) 1976-02-01
DK593975A (en) 1976-07-16
AU1006076A (en) 1977-07-14
LU74170A1 (en) 1976-12-31
SE7514776L (en) 1976-07-16
FR2297615A1 (en) 1976-08-13
AR213168A1 (en) 1978-12-29
ES444259A1 (en) 1977-10-01
GB1490671A (en) 1977-11-02
SU633471A3 (en) 1978-11-15
DE2601137A1 (en) 1976-07-22
PL101099B1 (en) 1978-11-30
DD124598A5 (en) 1977-03-02
BG25074A3 (en) 1978-07-12

Similar Documents

Publication Publication Date Title
PH11118A (en) Skin composition
JPS51144723A (en) Antiitumor agent
JPS5253851A (en) Novel sterile agent
JPS51122091A (en) Antiibacterial agent
JPS5214798A (en) Antiibacterial agent
ZA764889B (en) Skin composition
JPS51125202A (en) Novel substituted perhaloalkylamidines as cardiac agent
JPS525787A (en) Antiibacterial agent
GB1557482A (en) Substituted tetranorprostaglandins
JPS5261231A (en) Antiitumor agent
JPS51112527A (en) Antiivirus agent
PT65068A (en) Dishwashing composition
JPS5215826A (en) Medical composition
JPS5534285A (en) Solution composition
ZA766967B (en) Smell-removing agent
JPS5268195A (en) Antiibacterial agent
JPS5253844A (en) Novel antiifertile agent
JPS529638A (en) Tinnelectroplating solution
AU1100676A (en) Anti-histomonal composition
JPS527420A (en) Antimelancholia agent
JPS5265276A (en) Substituted tetraalkylpiperidinee44oxime
AU1735076A (en) Substituted sulfoximides
JPS5253845A (en) Novel antiifertile agent
ZA757951B (en) Pyrazoliums as fungicides
JPS51112447A (en) Antiiscale agent