PT64673B - Procede pour la preparation de nouvelles perhaloalcoylamidines substituees utilisees comme stimulants cardiaques - Google Patents

Procede pour la preparation de nouvelles perhaloalcoylamidines substituees utilisees comme stimulants cardiaques

Info

Publication number
PT64673B
PT64673B PT64673A PT6467376A PT64673B PT 64673 B PT64673 B PT 64673B PT 64673 A PT64673 A PT 64673A PT 6467376 A PT6467376 A PT 6467376A PT 64673 B PT64673 B PT 64673B
Authority
PT
Portugal
Prior art keywords
perhaloalcoylamidines
preparation
new substituted
cardiac stimulants
stimulants
Prior art date
Application number
PT64673A
Other languages
English (en)
French (fr)
Other versions
PT64673A (fr
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PT64673A publication Critical patent/PT64673A/pt
Publication of PT64673B publication Critical patent/PT64673B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827X being H
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/42Oxygen atoms attached in position 3 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/203Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PT64673A 1975-01-15 1976-01-05 Procede pour la preparation de nouvelles perhaloalcoylamidines substituees utilisees comme stimulants cardiaques PT64673B (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54130875A 1975-01-15 1975-01-15
US62973575A 1975-11-10 1975-11-10

Publications (2)

Publication Number Publication Date
PT64673A PT64673A (fr) 1976-02-01
PT64673B true PT64673B (fr) 1978-01-04

Family

ID=27066677

Family Applications (1)

Application Number Title Priority Date Filing Date
PT64673A PT64673B (fr) 1975-01-15 1976-01-05 Procede pour la preparation de nouvelles perhaloalcoylamidines substituees utilisees comme stimulants cardiaques

Country Status (21)

Country Link
JP (1) JPS51125202A (pt)
AR (1) AR213168A1 (pt)
AU (1) AU499649B2 (pt)
BG (1) BG25074A3 (pt)
CS (1) CS189737B2 (pt)
DD (1) DD124598A5 (pt)
DE (1) DE2601137A1 (pt)
DK (1) DK593975A (pt)
ES (1) ES444259A1 (pt)
FI (1) FI753673A (pt)
FR (1) FR2297615A1 (pt)
GB (1) GB1490671A (pt)
IL (1) IL48784A0 (pt)
LU (1) LU74170A1 (pt)
NL (1) NL7515256A (pt)
NO (1) NO754426L (pt)
NZ (1) NZ179730A (pt)
PL (1) PL101099B1 (pt)
PT (1) PT64673B (pt)
SE (1) SE7514776L (pt)
SU (1) SU633471A3 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423246A (en) 1982-02-22 1983-12-27 Olin Corporation Selected trichloroacetamidines
US4709052A (en) * 1983-05-31 1987-11-24 Sumitomo Chemical Company, Limited Soil disease-controlling imides
DE3664768D1 (en) * 1985-12-13 1989-09-07 Lafon Labor 5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives, preparation process and medicinal use
WO1992004054A1 (en) * 1990-08-30 1992-03-19 STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALTH SCIENCES UNIVERSITY, PORTLAND, OREGON, and THE UNIVERSITY OF OREGON, EUGENE, OREGON, Johnson Hall, University of Oregon Substituted amidines having high binding to the sigma receptor and the use thereof
ES2055651B1 (es) * 1992-07-20 1995-03-01 Vita Invest Sa Procedimiento para la obtencion de nuevas amidinas derivadas de 3-aminoetilindoles.
GB9425701D0 (en) * 1994-12-20 1995-02-22 Wellcome Found Enzyme inhibitors
EP1586561A1 (en) * 2004-04-13 2005-10-19 Cephalon, Inc. Bicyclic aromatic sulfinyl derivatives
US7423176B2 (en) * 2004-04-13 2008-09-09 Cephalon, Inc. Bicyclic aromatic sulfinyl derivatives
MX2009012183A (es) 2007-05-10 2010-04-27 Constar Int Inc Moleculas depuradoras del oxigeno, articulos que contienen las mismas y sus metodos de uso.
US7807705B2 (en) 2007-05-18 2010-10-05 The Ohio State University Research Foundation Potent indole-3-carbinol-derived antitumor agents
US8153680B2 (en) 2009-08-25 2012-04-10 The Ohio State University Research Foundation Alkyl indole-3-carbinol-derived antitumor agents
PL2483342T3 (pl) 2009-09-29 2017-08-31 Plastipak Packaging, Inc. Kompozycje kompatybilnego ze środkiem barwiącym polimeru zmiatającego tlen i wykonane z nich wyroby
AU2010319298B2 (en) 2009-11-13 2015-11-05 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
WO2011060297A2 (en) 2009-11-13 2011-05-19 Constar International, Inc. Oxygen scavengers, composition comprising the scavengers, and articles made from the compositions
KR20150021031A (ko) 2012-04-30 2015-02-27 프라스틱팩 팩키징, 인코퍼레이티드 산소 제거 조성물
US11338983B2 (en) 2014-08-22 2022-05-24 Plastipak Packaging, Inc. Oxygen scavenging compositions, articles containing same, and methods of their use
US10351692B2 (en) 2014-10-17 2019-07-16 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions

Also Published As

Publication number Publication date
FR2297615A1 (fr) 1976-08-13
FI753673A (pt) 1976-07-16
AU499649B2 (en) 1979-04-26
CS189737B2 (en) 1979-04-30
AR213168A1 (es) 1978-12-29
NL7515256A (nl) 1976-07-19
DK593975A (da) 1976-07-16
IL48784A0 (en) 1976-03-31
SU633471A3 (ru) 1978-11-15
ES444259A1 (es) 1977-10-01
NZ179730A (en) 1978-07-10
NO754426L (pt) 1976-07-16
JPS51125202A (en) 1976-11-01
DE2601137A1 (de) 1976-07-22
PT64673A (fr) 1976-02-01
BG25074A3 (en) 1978-07-12
SE7514776L (sv) 1976-07-16
GB1490671A (en) 1977-11-02
PL101099B1 (pl) 1978-11-30
DD124598A5 (pt) 1977-03-02
LU74170A1 (pt) 1976-12-31
AU1006076A (en) 1977-07-14

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