FR2297615A1 - Nouvelles perhalogenoalcoylamidines substituees comme stimulants cardiaques - Google Patents

Nouvelles perhalogenoalcoylamidines substituees comme stimulants cardiaques

Info

Publication number
FR2297615A1
FR2297615A1 FR7600562A FR7600562A FR2297615A1 FR 2297615 A1 FR2297615 A1 FR 2297615A1 FR 7600562 A FR7600562 A FR 7600562A FR 7600562 A FR7600562 A FR 7600562A FR 2297615 A1 FR2297615 A1 FR 2297615A1
Authority
FR
France
Prior art keywords
perhalogenoalcoylamidines
substituted
new
heart stimulants
stimulants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7600562A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of FR2297615A1 publication Critical patent/FR2297615A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827—X being H
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FR7600562A 1975-01-15 1976-01-12 Nouvelles perhalogenoalcoylamidines substituees comme stimulants cardiaques Withdrawn FR2297615A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54130875A 1975-01-15 1975-01-15
US62973575A 1975-11-10 1975-11-10

Publications (1)

Publication Number Publication Date
FR2297615A1 true FR2297615A1 (fr) 1976-08-13

Family

ID=27066677

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7600562A Withdrawn FR2297615A1 (fr) 1975-01-15 1976-01-12 Nouvelles perhalogenoalcoylamidines substituees comme stimulants cardiaques

Country Status (21)

Country Link
JP (1) JPS51125202A (fr)
AR (1) AR213168A1 (fr)
AU (1) AU499649B2 (fr)
BG (1) BG25074A3 (fr)
CS (1) CS189737B2 (fr)
DD (1) DD124598A5 (fr)
DE (1) DE2601137A1 (fr)
DK (1) DK593975A (fr)
ES (1) ES444259A1 (fr)
FI (1) FI753673A (fr)
FR (1) FR2297615A1 (fr)
GB (1) GB1490671A (fr)
IL (1) IL48784A0 (fr)
LU (1) LU74170A1 (fr)
NL (1) NL7515256A (fr)
NO (1) NO754426L (fr)
NZ (1) NZ179730A (fr)
PL (1) PL101099B1 (fr)
PT (1) PT64673B (fr)
SE (1) SE7514776L (fr)
SU (1) SU633471A3 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0580539A2 (fr) * 1992-07-20 1994-01-26 Vita-Invest, S.A. Amidines, dérivés de 3-aminoéthyl-indoles, pour le traitement de la migraine

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423246A (en) 1982-02-22 1983-12-27 Olin Corporation Selected trichloroacetamidines
US4709052A (en) * 1983-05-31 1987-11-24 Sumitomo Chemical Company, Limited Soil disease-controlling imides
EP0226511B1 (fr) * 1985-12-13 1989-08-02 LABORATOIRE L. LAFON Société anonyme dite: Dérivés de 5-phényl-1,4,5,6-tétrahydropyrimidine, procédé de préparation et utilisation en thérapeutique
CA2089261A1 (fr) * 1990-08-30 1992-03-01 John F.W. Keana Amidines substituees a fort pouvoir liant avec le recepteur sigma
GB9425701D0 (en) 1994-12-20 1995-02-22 Wellcome Found Enzyme inhibitors
EP1586561A1 (fr) * 2004-04-13 2005-10-19 Cephalon, Inc. Dérivés bicycliques aromatiques de sulfinyle
US7423176B2 (en) 2004-04-13 2008-09-09 Cephalon, Inc. Bicyclic aromatic sulfinyl derivatives
CA2687081C (fr) 2007-05-10 2016-09-13 Constar International, Inc. Molecules absorbant l'oxygene, articles contenant celles-ci et procedes d'utilisation de ceux-ci
WO2008144263A1 (fr) * 2007-05-18 2008-11-27 The Ohio State University Research Foundation Agents antitumoraux efficaces dérivés de l'indole-3-carbinole
US8153680B2 (en) 2009-08-25 2012-04-10 The Ohio State University Research Foundation Alkyl indole-3-carbinol-derived antitumor agents
AU2010303748B2 (en) 2009-09-29 2016-09-29 Plastipak Packaging, Inc. Colorant compatible oxygen scavenging polymer compositions and articles made from same
EP2499195B1 (fr) 2009-11-13 2020-12-09 Plastipak Packaging, Inc. Adsorbants d'oxygène, compositions comprenant les adsorbants, et articles réalisés à partir des compositions
AU2010319384B2 (en) 2009-11-13 2016-09-15 Plastipak Packaging, Inc. Oxygen scavengers, composition comprising the scavengers, and articles made from the compositions
NZ723792A (en) 2012-04-30 2017-12-22 Plastipak Packaging Inc Oxygen scavenging compositions
US11338983B2 (en) 2014-08-22 2022-05-24 Plastipak Packaging, Inc. Oxygen scavenging compositions, articles containing same, and methods of their use
US10351692B2 (en) 2014-10-17 2019-07-16 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0580539A2 (fr) * 1992-07-20 1994-01-26 Vita-Invest, S.A. Amidines, dérivés de 3-aminoéthyl-indoles, pour le traitement de la migraine
EP0580539A3 (en) * 1992-07-20 1994-05-18 Vita Invest Sa Amidines derived from 3-aminoethyl indoles for the treatment of migraines

Also Published As

Publication number Publication date
DE2601137A1 (de) 1976-07-22
SE7514776L (sv) 1976-07-16
GB1490671A (en) 1977-11-02
CS189737B2 (en) 1979-04-30
BG25074A3 (en) 1978-07-12
PL101099B1 (pl) 1978-11-30
AR213168A1 (es) 1978-12-29
JPS51125202A (en) 1976-11-01
DK593975A (da) 1976-07-16
DD124598A5 (fr) 1977-03-02
PT64673A (fr) 1976-02-01
FI753673A (fr) 1976-07-16
NZ179730A (en) 1978-07-10
NL7515256A (nl) 1976-07-19
ES444259A1 (es) 1977-10-01
NO754426L (fr) 1976-07-16
IL48784A0 (en) 1976-03-31
SU633471A3 (ru) 1978-11-15
AU1006076A (en) 1977-07-14
LU74170A1 (fr) 1976-12-31
AU499649B2 (en) 1979-04-26
PT64673B (fr) 1978-01-04

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Legal Events

Date Code Title Description
ST Notification of lapse