GB1488209A - Nuclease resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid - Google Patents
Nuclease resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acidInfo
- Publication number
- GB1488209A GB1488209A GB38314/75A GB3831475A GB1488209A GB 1488209 A GB1488209 A GB 1488209A GB 38314/75 A GB38314/75 A GB 38314/75A GB 3831475 A GB3831475 A GB 3831475A GB 1488209 A GB1488209 A GB 1488209A
- Authority
- GB
- United Kingdom
- Prior art keywords
- complex
- polyriboinosinic
- poly
- polyribocytidylic acid
- lysine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 5
- 101710163270 Nuclease Proteins 0.000 title abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 4
- 229920002134 Carboxymethyl cellulose Polymers 0.000 abstract 3
- 239000004472 Lysine Substances 0.000 abstract 3
- 239000001768 carboxy methyl cellulose Substances 0.000 abstract 3
- 239000008112 carboxymethyl-cellulose Substances 0.000 abstract 3
- 235000010948 carboxy methyl cellulose Nutrition 0.000 abstract 2
- 238000003756 stirring Methods 0.000 abstract 2
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/509,966 US3952097A (en) | 1974-09-27 | 1974-09-27 | Nuclease-resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1488209A true GB1488209A (en) | 1977-10-12 |
Family
ID=24028821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB38314/75A Expired GB1488209A (en) | 1974-09-27 | 1975-09-18 | Nuclease resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3952097A (https=) |
| JP (1) | JPS5186484A (https=) |
| BE (1) | BE833838A (https=) |
| CA (2) | CA1038375A (https=) |
| CH (1) | CH616432A5 (https=) |
| DE (1) | DE2543214A1 (https=) |
| FR (1) | FR2285893A1 (https=) |
| GB (1) | GB1488209A (https=) |
| HU (1) | HU174918B (https=) |
| IL (1) | IL48099A (https=) |
| NL (1) | NL7511370A (https=) |
| SE (1) | SE403783B (https=) |
| ZA (1) | ZA755865B (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4024241A (en) * | 1974-09-27 | 1977-05-17 | The United States Of America As Represented By The Secretary Of Health, Education And Welfare | Nuclease-resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid |
| FR2475900A1 (fr) * | 1980-02-20 | 1981-08-21 | Fabre Sa Pierre | Complexe vaccinal contenant un antigene specifique et vaccin le contenant |
| US4388306A (en) * | 1980-06-04 | 1983-06-14 | Merck & Co., Inc. | Pharmaceutical composition comprising modified polyriboinosinic-polyribocytidylic acid, for induction of interferon in primates |
| US4389395A (en) * | 1981-01-09 | 1983-06-21 | Lerner A Martin | Low molecular weight complex of polyriboinosinic-polyribocytidylic acid and method of inducing interferon |
| US7229822B1 (en) * | 2000-02-29 | 2007-06-12 | Univ Columbia | Melanoma differentation associated gene-5 and vectors and cells containing same |
| AU2005332599B2 (en) * | 2005-06-08 | 2012-02-16 | Yisheng Biopharma (Singapore) Pte. Ltd. | Polyinosinic acid-polycytidylic acid-based adjuvant |
| US20070166800A1 (en) * | 2006-01-13 | 2007-07-19 | Haixiang Lin | Immunogenic substances comprising a polyinosinic acid-polycytidilic acid based adjuvant |
| US20070166239A1 (en) * | 2006-01-13 | 2007-07-19 | Haixiang Lin | Mucosal immunogenic substances comprising a polyinosinic acid - polycytidilic acid based adjuvant |
| KR20100051041A (ko) * | 2007-03-07 | 2010-05-14 | 엔벤타 바이오파마슈티칼스 코퍼레이션 | 이중-가닥 봉쇄형 핵산 조성물 |
| WO2009155489A2 (en) | 2008-06-19 | 2009-12-23 | Variation Biotechnologies, Inc. | Compositions and methods for treating influenza |
| US20110097418A1 (en) * | 2009-05-29 | 2011-04-28 | Variation Biotechnologies, Inc. | Compositions and methods for treating influenza |
| AU2010270722B2 (en) | 2009-07-06 | 2015-06-04 | Variation Biotechnologies, Inc. | Methods for preparing vesicles and formulations produced therefrom |
| US9907746B2 (en) | 2009-07-06 | 2018-03-06 | Variation Biotechnologies, Inc. | Methods for preparing vesicles and formulations produced therefrom |
| MX342138B (es) | 2010-07-06 | 2016-09-14 | Variation Biotechnologies Inc | Composiciones y metodos para el tratamiento de influenza. |
| CA2862871C (en) | 2011-01-13 | 2020-09-22 | Variation Biotechnologies Inc. | Methods for preparing vesicles and formulations produced therefrom |
| CA2862864C (en) | 2011-01-13 | 2018-12-11 | Variation Biotechnologies Inc. | Compositions and methods for treating viral infections |
| US20140356399A1 (en) | 2012-01-12 | 2014-12-04 | Variation Biotechnologies, Inc. | Compositions and methods for treating viral infections |
| US20150079077A1 (en) | 2012-01-27 | 2015-03-19 | Variation Biotechnologies, Inc. | Methods and compositions for therapeutic agents |
| RU2678981C2 (ru) | 2014-12-23 | 2019-02-05 | Йишенг Байофарма (Сингапур) Пте Лтд | Композиция от бешенства, содержащая адъювант pika |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2851453A (en) * | 1954-08-09 | 1958-09-09 | Smith Kline French Lab | Cellulose derivative product, compositions comprising the same and their preparation |
| US3066075A (en) * | 1960-07-25 | 1962-11-27 | G W Carnrick Co | Compositions comprising amphetamine and carboxymethyl cellulose in chemically combined form |
| US3493559A (en) * | 1967-05-29 | 1970-02-03 | Upjohn Co | 2-thiocytosine ribofuranosides |
| BE757291A (fr) * | 1969-10-10 | 1971-04-09 | Smith Kline French Lab | Complexe antiviral de arn et d'un polysaccharide |
| GB1364987A (en) * | 1971-06-19 | 1974-08-29 | Merck Patent Gmbh | Biologically active two component complexes |
| BE790953A (fr) * | 1971-11-05 | 1973-05-03 | Beecham Group Ltd | Matiere biologiquement active |
| US3853846A (en) * | 1973-02-12 | 1974-12-10 | Abbott Lab | INOSINE-5 -Carboxylates |
-
1974
- 1974-09-27 US US05/509,966 patent/US3952097A/en not_active Expired - Lifetime
-
1975
- 1975-09-12 IL IL48099A patent/IL48099A/xx unknown
- 1975-09-15 ZA ZA00755865A patent/ZA755865B/xx unknown
- 1975-09-18 GB GB38314/75A patent/GB1488209A/en not_active Expired
- 1975-09-22 HU HU75GO1322A patent/HU174918B/hu unknown
- 1975-09-24 CH CH1240375A patent/CH616432A5/de not_active IP Right Cessation
- 1975-09-25 BE BE6045184A patent/BE833838A/xx unknown
- 1975-09-25 FR FR7529368A patent/FR2285893A1/fr active Granted
- 1975-09-26 CA CA236,465A patent/CA1038375A/en not_active Expired
- 1975-09-26 JP JP50117079A patent/JPS5186484A/ja active Pending
- 1975-09-26 SE SE7510812A patent/SE403783B/xx unknown
- 1975-09-26 NL NL7511370A patent/NL7511370A/xx not_active Application Discontinuation
- 1975-09-27 DE DE19752543214 patent/DE2543214A1/de not_active Withdrawn
-
1980
- 1980-08-15 CA CA358,389A patent/CA1091648B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3952097A (en) | 1976-04-20 |
| IL48099A (en) | 1978-04-30 |
| FR2285893A1 (fr) | 1976-04-23 |
| ZA755865B (en) | 1976-08-25 |
| CA1091648B (en) | 1980-12-16 |
| SE7510812L (sv) | 1976-03-29 |
| IL48099A0 (en) | 1975-11-25 |
| DE2543214A1 (de) | 1976-05-20 |
| NL7511370A (nl) | 1976-03-30 |
| CH616432A5 (https=) | 1980-03-31 |
| JPS5186484A (en) | 1976-07-29 |
| BE833838A (fr) | 1976-01-16 |
| CA1038375A (en) | 1978-09-12 |
| FR2285893B1 (https=) | 1980-08-08 |
| SE403783B (sv) | 1978-09-04 |
| HU174918B (hu) | 1980-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 49R | Reference inserted (sect. 9/1949) | ||
| SP | Amendment (slips) printed | ||
| PS | Patent sealed [section 19, patents act 1949] | ||
| 746 | Register noted 'licences of right' (sect. 46/1977) | ||
| PCNP | Patent ceased through non-payment of renewal fee |