GB1476422A - Biological extracts - Google Patents
Biological extractsInfo
- Publication number
- GB1476422A GB1476422A GB914973A GB914973A GB1476422A GB 1476422 A GB1476422 A GB 1476422A GB 914973 A GB914973 A GB 914973A GB 914973 A GB914973 A GB 914973A GB 1476422 A GB1476422 A GB 1476422A
- Authority
- GB
- United Kingdom
- Prior art keywords
- glycopeptide
- infra
- cells
- immunostimulating
- red
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000284 extract Substances 0.000 title 1
- DQJCDTNMLBYVAY-ZXXIYAEKSA-N (2S,5R,10R,13R)-16-{[(2R,3S,4R,5R)-3-{[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-(ethylamino)-6-hydroxy-2-(hydroxymethyl)oxan-4-yl]oxy}-5-(4-aminobutyl)-10-carbamoyl-2,13-dimethyl-4,7,12,15-tetraoxo-3,6,11,14-tetraazaheptadecan-1-oic acid Chemical compound NCCCC[C@H](C(=O)N[C@@H](C)C(O)=O)NC(=O)CC[C@H](C(N)=O)NC(=O)[C@@H](C)NC(=O)C(C)O[C@@H]1[C@@H](NCC)C(O)O[C@H](CO)[C@H]1O[C@H]1[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O1 DQJCDTNMLBYVAY-ZXXIYAEKSA-N 0.000 abstract 6
- 108010015899 Glycopeptides Proteins 0.000 abstract 6
- 102000002068 Glycopeptides Human genes 0.000 abstract 6
- 241000894006 Bacteria Species 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- 210000004027 cell Anatomy 0.000 abstract 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 abstract 3
- 230000003308 immunostimulating effect Effects 0.000 abstract 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 abstract 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 241000699670 Mus sp. Species 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 2
- 230000002051 biphasic effect Effects 0.000 abstract 2
- 238000000605 extraction Methods 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
- 241000203716 Actinomycetaceae Species 0.000 abstract 1
- 241001046548 Anaerobium Species 0.000 abstract 1
- 241001307956 Chorioptes bovis Species 0.000 abstract 1
- 241000186216 Corynebacterium Species 0.000 abstract 1
- 241000186225 Corynebacterium pseudotuberculosis Species 0.000 abstract 1
- 241000186246 Corynebacterium renale Species 0.000 abstract 1
- 241000186427 Cutibacterium acnes Species 0.000 abstract 1
- 241001464975 Cutibacterium granulosum Species 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 241001506004 Porotermes adamsoni Species 0.000 abstract 1
- 241001464976 Propionimicrobium lymphophilum Species 0.000 abstract 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- 241000186064 Trueperella pyogenes Species 0.000 abstract 1
- 235000021258 carbohydrate absorption Nutrition 0.000 abstract 1
- 210000002421 cell wall Anatomy 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 230000009089 cytolysis Effects 0.000 abstract 1
- 238000003306 harvesting Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 239000011780 sodium chloride Substances 0.000 abstract 1
- 210000000952 spleen Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB914973A GB1476422A (en) | 1973-02-23 | 1973-02-23 | Biological extracts |
| FR7406104A FR2218888B1 (enExample) | 1973-02-23 | 1974-02-22 | |
| CH257874A CH602920A5 (enExample) | 1973-02-23 | 1974-02-22 | |
| BE141321A BE811491A (fr) | 1973-02-23 | 1974-02-22 | Extraits biologiques |
| DK96174AA DK141757B (da) | 1973-02-23 | 1974-02-22 | Fremgangsmåde til fremstilling af et immunostimulerende glycopeptid fra Corynebacterium parvum. |
| IE367/74A IE39332B1 (en) | 1973-02-23 | 1974-02-22 | Biological extracts |
| NL7402455A NL7402455A (enExample) | 1973-02-23 | 1974-02-22 | |
| ZA00741189A ZA741189B (en) | 1973-02-23 | 1974-02-22 | Biological extracts |
| IL44267A IL44267A (en) | 1973-02-23 | 1974-02-22 | Glycopeptides, their preparation and pharmaceutical compositions containing them |
| DE19742408724 DE2408724A1 (de) | 1973-02-23 | 1974-02-22 | Biologische extrakte und verfahren zu ihrer herstellung |
| JP49021333A JPS5063196A (enExample) | 1973-02-23 | 1974-02-22 | |
| US05/445,309 US4010257A (en) | 1973-02-23 | 1974-02-22 | Biological extracts |
| AU65910/74A AU6591074A (en) | 1973-02-23 | 1974-02-22 | Glycoprotein from bacteria |
| CA193,265A CA1020460A (en) | 1973-02-23 | 1974-02-22 | Isolation of immunostimulating glycopeptide from bacteria |
| HU74WE501A HU173676B (hu) | 1973-02-23 | 1974-02-22 | Sposob poluchenija glukopeptidov |
| US05/588,313 US4069314A (en) | 1973-02-23 | 1975-06-19 | Glycopeptide extract |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB914973A GB1476422A (en) | 1973-02-23 | 1973-02-23 | Biological extracts |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1476422A true GB1476422A (en) | 1977-06-16 |
Family
ID=9866339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB914973A Expired GB1476422A (en) | 1973-02-23 | 1973-02-23 | Biological extracts |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS5063196A (enExample) |
| AU (1) | AU6591074A (enExample) |
| BE (1) | BE811491A (enExample) |
| DE (1) | DE2408724A1 (enExample) |
| DK (1) | DK141757B (enExample) |
| FR (1) | FR2218888B1 (enExample) |
| GB (1) | GB1476422A (enExample) |
| HU (1) | HU173676B (enExample) |
| IE (1) | IE39332B1 (enExample) |
| IL (1) | IL44267A (enExample) |
| NL (1) | NL7402455A (enExample) |
| ZA (1) | ZA741189B (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0024941A3 (en) * | 1979-08-30 | 1981-12-02 | Yamanouchi Pharmaceutical Co. Ltd. | Water-soluble extract from nonpathogenic aerobic corynebacteria, production thereof and compositions containing the extract |
| WO2016009377A1 (en) * | 2014-07-16 | 2016-01-21 | Depofarma S.P.A. | Propionibacterium acnes and granulosum parietal fraction having immunomodulating action |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2410476B1 (fr) * | 1977-11-30 | 1980-08-22 | Inst Nat Sante Rech Med | Application des peptidoglycanes extraits de bacteries, en particulier des bacillus a titre de medicaments, notamment stimulant l'immunite antitumorale |
| FR2480604A1 (fr) * | 1980-04-22 | 1981-10-23 | Pasteur Institut | Fractions nouvelles extraites de bacteries aerobies, douees de proprietes antitumorales, antibacteriennes et inductrices d'interferon et leur procede de preparation |
| FR2502496A2 (fr) * | 1981-03-30 | 1982-10-01 | Pasteur Institut | Fractions nouvelles extraites de bacteries aerobies, douees de proprietes antitumorales, antibacteriennes et inductrices d'interferon, et leur procede de preparation |
| US4479935A (en) * | 1980-04-22 | 1984-10-30 | Institut Pasteur | Fractions extracted from aerobic bacteria, endowed with antitumoral, antibacterial and interferon inducing properties, and process for their preparation |
| US4871488A (en) * | 1985-04-22 | 1989-10-03 | Albany Medical College Of Union University | Reconstituting viral glycoproteins into large phospholipid vesicles |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3450815A (en) * | 1964-04-24 | 1969-06-17 | Princeton Lab Inc | Method of stimulating a host defense mechanism with an actinovaccine |
| US3529057A (en) * | 1964-08-14 | 1970-09-15 | Takeda Chemical Industries Ltd | Purified periodic acid-oxidized mucopeptide of mycobacteria cell walls constituting a vaccine enhancing nonspecific host resistance against pathogenic bacterial infections |
-
1973
- 1973-02-23 GB GB914973A patent/GB1476422A/en not_active Expired
-
1974
- 1974-02-22 AU AU65910/74A patent/AU6591074A/en not_active Expired
- 1974-02-22 DE DE19742408724 patent/DE2408724A1/de not_active Withdrawn
- 1974-02-22 IE IE367/74A patent/IE39332B1/xx unknown
- 1974-02-22 ZA ZA00741189A patent/ZA741189B/xx unknown
- 1974-02-22 JP JP49021333A patent/JPS5063196A/ja active Pending
- 1974-02-22 HU HU74WE501A patent/HU173676B/hu unknown
- 1974-02-22 IL IL44267A patent/IL44267A/xx unknown
- 1974-02-22 BE BE141321A patent/BE811491A/xx unknown
- 1974-02-22 NL NL7402455A patent/NL7402455A/xx not_active Application Discontinuation
- 1974-02-22 FR FR7406104A patent/FR2218888B1/fr not_active Expired
- 1974-02-22 DK DK96174AA patent/DK141757B/da unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0024941A3 (en) * | 1979-08-30 | 1981-12-02 | Yamanouchi Pharmaceutical Co. Ltd. | Water-soluble extract from nonpathogenic aerobic corynebacteria, production thereof and compositions containing the extract |
| WO2016009377A1 (en) * | 2014-07-16 | 2016-01-21 | Depofarma S.P.A. | Propionibacterium acnes and granulosum parietal fraction having immunomodulating action |
| JP2017526382A (ja) * | 2014-07-16 | 2017-09-14 | デポファルマ ソチエタ ペル アツィオニＤｅｐｏｆａｒｍａ Ｓ．Ｐ．Ａ． | 免疫調節作用を有するプロピオニバクテリウム・アクネスおよびプロピオニバクテリウム・グラヌローサムの細胞壁画分 |
| US10576109B2 (en) | 2014-07-16 | 2020-03-03 | Depofarma S.P.A. | Propionibacterium acnes and granulosum parietal fraction having immunomodulating action |
Also Published As
| Publication number | Publication date |
|---|---|
| IE39332B1 (en) | 1978-09-13 |
| HU173676B (hu) | 1979-07-28 |
| AU6591074A (en) | 1975-08-28 |
| IL44267A (en) | 1978-07-31 |
| NL7402455A (enExample) | 1974-08-27 |
| DK141757B (da) | 1980-06-09 |
| DE2408724A1 (de) | 1974-09-05 |
| JPS5063196A (enExample) | 1975-05-29 |
| BE811491A (fr) | 1974-08-22 |
| FR2218888B1 (enExample) | 1976-12-03 |
| IL44267A0 (en) | 1974-05-16 |
| DK141757C (enExample) | 1980-10-27 |
| FR2218888A1 (enExample) | 1974-09-20 |
| IE39332L (en) | 1974-08-23 |
| ZA741189B (en) | 1975-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |