GB1476262A - 11,12-secoprostaglandins - Google Patents
11,12-secoprostaglandinsInfo
- Publication number
- GB1476262A GB1476262A GB2579775A GB2579775A GB1476262A GB 1476262 A GB1476262 A GB 1476262A GB 2579775 A GB2579775 A GB 2579775A GB 2579775 A GB2579775 A GB 2579775A GB 1476262 A GB1476262 A GB 1476262A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ester
- secoprostaglandins
- dioxothia
- oxothia
- thia
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- UKWHYYKOEPRTIC-UHFFFAOYSA-N mercury(ii) oxide Chemical compound [Hg]=O UKWHYYKOEPRTIC-UHFFFAOYSA-N 0.000 abstract 2
- IYXGSMUGOJNHAZ-UHFFFAOYSA-N Ethyl malonate Chemical class CCOC(=O)CC(=O)OCC IYXGSMUGOJNHAZ-UHFFFAOYSA-N 0.000 abstract 1
- LSDPWZHWYPCBBB-UHFFFAOYSA-N Methanethiol Chemical compound SC LSDPWZHWYPCBBB-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 150000002690 malonic acid derivatives Chemical class 0.000 abstract 1
- 230000002997 prostaglandinlike Effects 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48317874A | 1974-06-25 | 1974-06-25 | |
| US56656675A | 1975-04-09 | 1975-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1476262A true GB1476262A (en) | 1977-06-10 |
Family
ID=27047557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2579775A Expired GB1476262A (en) | 1974-06-25 | 1975-06-17 | 11,12-secoprostaglandins |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS51125020A (en, 2012) |
| CA (1) | CA1064961A (en, 2012) |
| CH (1) | CH614935A5 (en, 2012) |
| DE (1) | DE2528070A1 (en, 2012) |
| DK (1) | DK263775A (en, 2012) |
| ES (1) | ES438765A1 (en, 2012) |
| FI (1) | FI751730A7 (en, 2012) |
| FR (1) | FR2276037A1 (en, 2012) |
| GB (1) | GB1476262A (en, 2012) |
| IE (1) | IE41258B1 (en, 2012) |
| IL (1) | IL47487A (en, 2012) |
| LU (1) | LU72797A1 (en, 2012) |
| NL (1) | NL7507020A (en, 2012) |
| NO (1) | NO142219C (en, 2012) |
| NZ (1) | NZ177843A (en, 2012) |
| SE (1) | SE7506804L (en, 2012) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010518108A (ja) * | 2007-02-06 | 2010-05-27 | ユニバーシティ オブ ルーイビル リサーチ ファウンデーション，インコーポレーテッド | 治療化合物 |
| AU2012225574A1 (en) | 2011-03-07 | 2013-09-26 | University Of Louisville Research Foundation, Inc. | Predictive marker of DNMT1 inhibitor therapeutic efficacy and methods of using the marker |
| WO2014039860A2 (en) | 2012-09-07 | 2014-03-13 | University Of Louisville Research Foundation, Inc. | Compositions and methods for modulating dnmt1 inhibitor activity |
-
1975
- 1975-06-10 FI FI751730A patent/FI751730A7/fi not_active Application Discontinuation
- 1975-06-11 DK DK263775A patent/DK263775A/da unknown
- 1975-06-12 NL NL7507020A patent/NL7507020A/xx not_active Application Discontinuation
- 1975-06-12 NO NO752091A patent/NO142219C/no unknown
- 1975-06-13 SE SE7506804A patent/SE7506804L/xx unknown
- 1975-06-16 IL IL47487A patent/IL47487A/xx unknown
- 1975-06-16 NZ NZ177843A patent/NZ177843A/xx unknown
- 1975-06-17 GB GB2579775A patent/GB1476262A/en not_active Expired
- 1975-06-18 FR FR7519087A patent/FR2276037A1/fr active Granted
- 1975-06-18 CA CA229,586A patent/CA1064961A/en not_active Expired
- 1975-06-19 IE IE1371/75A patent/IE41258B1/xx unknown
- 1975-06-20 ES ES438765A patent/ES438765A1/es not_active Expired
- 1975-06-24 LU LU72797A patent/LU72797A1/xx unknown
- 1975-06-24 DE DE19752528070 patent/DE2528070A1/de not_active Withdrawn
- 1975-06-24 CH CH820875A patent/CH614935A5/xx not_active IP Right Cessation
- 1975-06-25 JP JP50077579A patent/JPS51125020A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NZ177843A (en) | 1978-04-03 |
| ES438765A1 (es) | 1977-07-01 |
| NO752091L (en, 2012) | 1975-12-30 |
| JPS51125020A (en) | 1976-11-01 |
| DK263775A (da) | 1975-12-26 |
| NO142219B (no) | 1980-04-08 |
| AU8221675A (en) | 1976-12-23 |
| NO142219C (no) | 1980-07-16 |
| IE41258B1 (en) | 1979-11-21 |
| NL7507020A (nl) | 1975-12-30 |
| DE2528070A1 (de) | 1976-01-08 |
| FI751730A7 (en, 2012) | 1975-12-26 |
| CH614935A5 (en) | 1979-12-28 |
| SE7506804L (sv) | 1975-12-29 |
| FR2276037A1 (fr) | 1976-01-23 |
| IL47487A0 (en) | 1975-08-31 |
| IE41258L (en) | 1975-12-25 |
| LU72797A1 (en, 2012) | 1976-04-13 |
| IL47487A (en) | 1979-05-31 |
| CA1064961A (en) | 1979-10-23 |
| FR2276037B1 (en, 2012) | 1979-03-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |