GB1466991A - A4-1-y-phenylpropyl-piperidinyl-amino coumarin and a method for its preparation - Google Patents
A4-1-y-phenylpropyl-piperidinyl-amino coumarin and a method for its preparationInfo
- Publication number
- GB1466991A GB1466991A GB279074A GB279074A GB1466991A GB 1466991 A GB1466991 A GB 1466991A GB 279074 A GB279074 A GB 279074A GB 279074 A GB279074 A GB 279074A GB 1466991 A GB1466991 A GB 1466991A
- Authority
- GB
- United Kingdom
- Prior art keywords
- phenylpropyl
- piperidinyl
- preparation
- amino
- amino coumarin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ZYGHJZDHTFUPRJ-UHFFFAOYSA-N benzo-alpha-pyrone Natural products C1=CC=C2OC(=O)C=CC2=C1 ZYGHJZDHTFUPRJ-UHFFFAOYSA-N 0.000 title 1
- 229960000956 coumarin Drugs 0.000 title 1
- 235000001671 coumarin Nutrition 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- FTWWEFSFFIMPQU-UHFFFAOYSA-N 1-(3-phenylpropyl)piperidin-4-amine Chemical compound C1CC(N)CCN1CCCC1=CC=CC=C1 FTWWEFSFFIMPQU-UHFFFAOYSA-N 0.000 abstract 1
- BTUHKFHHFOZJBA-UHFFFAOYSA-N 3-amino-4-piperidin-4-ylchromen-2-one Chemical compound N1CCC(CC1)C1=C(C(OC2=CC=CC=C12)=O)N BTUHKFHHFOZJBA-UHFFFAOYSA-N 0.000 abstract 1
- XMZQWZJMTBCUFT-UHFFFAOYSA-N 3-bromopropylbenzene Chemical compound BrCCCC1=CC=CC=C1 XMZQWZJMTBCUFT-UHFFFAOYSA-N 0.000 abstract 1
- NUKYPUAOHBNCPY-UHFFFAOYSA-N 4-aminopyridine Chemical compound NC1=CC=NC=C1 NUKYPUAOHBNCPY-UHFFFAOYSA-N 0.000 abstract 1
- 229960004979 fampridine Drugs 0.000 abstract 1
- 210000000653 nervous system Anatomy 0.000 abstract 1
- 125000004482 piperidin-4-yl group Chemical group N1CCC(CC1)* 0.000 abstract 1
- 230000000506 psychotropic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7222423A FR2189027B1 (enrdf_load_stackoverflow) | 1972-06-21 | 1972-06-21 | |
| FR7312523A FR2224145B2 (enrdf_load_stackoverflow) | 1972-06-21 | 1973-04-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1466991A true GB1466991A (en) | 1977-03-16 |
Family
ID=26217177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB279074A Expired GB1466991A (en) | 1972-06-21 | 1974-01-21 | A4-1-y-phenylpropyl-piperidinyl-amino coumarin and a method for its preparation |
Country Status (3)
| Country | Link |
|---|---|
| DE (2) | DE2331438A1 (enrdf_load_stackoverflow) |
| FR (2) | FR2189027B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1466991A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2156250C2 (ru) * | 1995-04-24 | 2000-09-20 | Новартис Аг | Производные хромона, способ их получения и фармацевтическая композиция |
| US8410271B2 (en) | 2004-09-30 | 2013-04-02 | Neurosearch A/S | Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19730989A1 (de) | 1997-07-18 | 1999-01-21 | Merck Patent Gmbh | Piperazin-Derivate |
| US6921821B2 (en) * | 2002-06-12 | 2005-07-26 | Abbott Laboratories | Antagonists of melanin concentrating hormone receptor |
| JP5001156B2 (ja) * | 2004-09-30 | 2012-08-15 | ノイロサーチ アクティーゼルスカブ | 新規クロメン−２−オン誘導体及びモノアミン神経伝達物質再取込阻害剤としてのその使用 |
| CA2999200C (en) | 2015-09-24 | 2021-03-30 | Guizhou Bailing Group Pharmaceutical Co., Ltd. | 4-substituted coumarin derivatives and preparation methods and uses thereof |
| CN109053705A (zh) * | 2018-09-19 | 2018-12-21 | 南京大学连云港高新技术研究院 | 一种5-氨基吡啶-3-羧酸甲酯衍生物C29H26N3MeO11的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH398637A (de) * | 1960-11-15 | 1966-03-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen Cumarinderivaten |
| BE758328A (fr) * | 1969-10-31 | 1971-04-30 | Beecham Group Ltd | Benzopyranne-5-ols et coumarines intermediaires |
-
1972
- 1972-06-21 FR FR7222423A patent/FR2189027B1/fr not_active Expired
-
1973
- 1973-04-06 FR FR7312523A patent/FR2224145B2/fr not_active Expired
- 1973-06-20 DE DE19732331438 patent/DE2331438A1/de active Pending
-
1974
- 1974-01-21 GB GB279074A patent/GB1466991A/en not_active Expired
- 1974-01-26 DE DE19742403786 patent/DE2403786A1/de active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2156250C2 (ru) * | 1995-04-24 | 2000-09-20 | Новартис Аг | Производные хромона, способ их получения и фармацевтическая композиция |
| US8410271B2 (en) | 2004-09-30 | 2013-04-02 | Neurosearch A/S | Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2189027B1 (enrdf_load_stackoverflow) | 1976-03-05 |
| FR2189027A1 (enrdf_load_stackoverflow) | 1974-01-25 |
| DE2331438A1 (de) | 1974-01-10 |
| DE2403786A1 (de) | 1974-10-24 |
| FR2224145B2 (enrdf_load_stackoverflow) | 1976-04-23 |
| FR2224145A2 (enrdf_load_stackoverflow) | 1974-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |