GB1466991A - A4-1-y-phenylpropyl-piperidinyl-amino coumarin and a method for its preparation - Google Patents

A4-1-y-phenylpropyl-piperidinyl-amino coumarin and a method for its preparation

Info

Publication number
GB1466991A
GB1466991A GB279074A GB279074A GB1466991A GB 1466991 A GB1466991 A GB 1466991A GB 279074 A GB279074 A GB 279074A GB 279074 A GB279074 A GB 279074A GB 1466991 A GB1466991 A GB 1466991A
Authority
GB
United Kingdom
Prior art keywords
phenylpropyl
piperidinyl
preparation
amino
amino coumarin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB279074A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leurquin SA Lab
Original Assignee
Leurquin SA Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leurquin SA Lab filed Critical Leurquin SA Lab
Publication of GB1466991A publication Critical patent/GB1466991A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1466991 4-Piperidin-4-yl amino-coumarin LABORATOIRES LEURQUIN SA 21 Jan 1974 [6 April 1973] 2790/74 Heading C2C Novel 4 - [1 - (y - phenylpropyl)piperidin - 4- yl]aminocoumarin (I) is prepared by reacting a 4-halocoumarin with 4-amino-1-γ-phenylpropylpiperidine (III). Compound (II) is prepared by reacting γ- bromo - phenylpropane with 4 - aminopyridine and reducing the quaternary salt formed with KBH 4 . Compound (I) has psychotropic activity and an action on the responses to the mediators of the autonomous nervous system.
GB279074A 1972-06-21 1974-01-21 A4-1-y-phenylpropyl-piperidinyl-amino coumarin and a method for its preparation Expired GB1466991A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7222423A FR2189027B1 (en) 1972-06-21 1972-06-21
FR7312523A FR2224145B2 (en) 1972-06-21 1973-04-06

Publications (1)

Publication Number Publication Date
GB1466991A true GB1466991A (en) 1977-03-16

Family

ID=26217177

Family Applications (1)

Application Number Title Priority Date Filing Date
GB279074A Expired GB1466991A (en) 1972-06-21 1974-01-21 A4-1-y-phenylpropyl-piperidinyl-amino coumarin and a method for its preparation

Country Status (3)

Country Link
DE (2) DE2331438A1 (en)
FR (2) FR2189027B1 (en)
GB (1) GB1466991A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8410271B2 (en) 2004-09-30 2013-04-02 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19730989A1 (en) 1997-07-18 1999-01-21 Merck Patent Gmbh Piperazine derivatives
JP2005532368A (en) * 2002-06-12 2005-10-27 アボット・ラボラトリーズ Melanin-concentrating hormone receptor antagonist
CN101023081A (en) * 2004-09-30 2007-08-22 神经研究公司 Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
AU2016327715B2 (en) * 2015-09-24 2019-05-16 Chengdu Zenitar Biomedical Technology Co., Ltd. 4-substituted coumarin derivatives and preparation methods and uses thereof
CN109053705A (en) * 2018-09-19 2018-12-21 南京大学连云港高新技术研究院 A kind of 5- aminopyridine-3-carboxylic acid methyl ester derivation C29H26N3MeO11Preparation method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH398637A (en) * 1960-11-15 1966-03-15 Geigy Ag J R Process for the production of new coumarin derivatives
BE758328A (en) * 1969-10-31 1971-04-30 Beecham Group Ltd BENZOPYRANNE-5-OLS AND INTERMEDIATE COUMARINS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8410271B2 (en) 2004-09-30 2013-04-02 Neurosearch A/S Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Also Published As

Publication number Publication date
DE2331438A1 (en) 1974-01-10
DE2403786A1 (en) 1974-10-24
FR2224145B2 (en) 1976-04-23
FR2189027A1 (en) 1974-01-25
FR2189027B1 (en) 1976-03-05
FR2224145A2 (en) 1974-10-31

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee