GB1466637A - Process for the preparation of d- - 2-p-hydroxyphenyl- glycyl chloride hydrochlorides - Google Patents
Process for the preparation of d- - 2-p-hydroxyphenyl- glycyl chloride hydrochloridesInfo
- Publication number
- GB1466637A GB1466637A GB2612975A GB2612975A GB1466637A GB 1466637 A GB1466637 A GB 1466637A GB 2612975 A GB2612975 A GB 2612975A GB 2612975 A GB2612975 A GB 2612975A GB 1466637 A GB1466637 A GB 1466637A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hydroxyphenyl
- glycyl chloride
- reaction mixture
- crystalline
- chloride hydrochloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- MRFJAULKKHVIGF-OGFXRTJISA-N (2r)-2-amino-2-(4-hydroxyphenyl)acetyl chloride;hydrochloride Chemical class Cl.ClC(=O)[C@H](N)C1=CC=C(O)C=C1 MRFJAULKKHVIGF-OGFXRTJISA-N 0.000 title 1
- 239000011541 reaction mixture Substances 0.000 abstract 5
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 4
- 239000012453 solvate Substances 0.000 abstract 4
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- LJCWONGJFPCTTL-SSDOTTSWSA-N D-4-hydroxyphenylglycine Chemical compound [O-]C(=O)[C@H]([NH3+])C1=CC=C(O)C=C1 LJCWONGJFPCTTL-SSDOTTSWSA-N 0.000 abstract 3
- 150000008064 anhydrides Chemical class 0.000 abstract 3
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 2
- ZAKRZZDABWCUGW-UHFFFAOYSA-N 2-aminoacetyl chloride;hydrochloride Chemical compound Cl.NCC(Cl)=O ZAKRZZDABWCUGW-UHFFFAOYSA-N 0.000 abstract 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- 238000010438 heat treatment Methods 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000010899 nucleation Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/44—Two oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US480895A US3925418A (en) | 1974-06-19 | 1974-06-19 | Hemisolvate of D-(-)-2-(p-hydroxyphenyl)glycyl chloride hydrochloride and process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1466637A true GB1466637A (en) | 1977-03-09 |
Family
ID=23909785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2612975A Expired GB1466637A (en) | 1974-06-19 | 1975-06-19 | Process for the preparation of d- - 2-p-hydroxyphenyl- glycyl chloride hydrochlorides |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3925418A (enExample) |
| JP (1) | JPS5858341B2 (enExample) |
| CH (1) | CH614189A5 (enExample) |
| DE (1) | DE2527235C2 (enExample) |
| FR (1) | FR2275445A1 (enExample) |
| GB (1) | GB1466637A (enExample) |
| IL (1) | IL47488A (enExample) |
| NL (1) | NL183030C (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1096213B (it) * | 1978-05-16 | 1985-08-26 | Chimica Bulciago Srl | Procedimento di clorurazione di alfa-amminoacidi |
| DE3065012D1 (en) * | 1979-04-25 | 1983-11-03 | Biochemie Gmbh | Process for the production of phenylglycyl chloride hydrochlorides |
| IT1113934B (it) * | 1979-05-03 | 1986-01-27 | Chimica Bulciago Srl | Procedimento perfezionato di clorurazione del gruppo carbossilico di alfa-amminoacidi |
| US4464307A (en) * | 1982-11-08 | 1984-08-07 | Zoecon Corporation | Substituted acid chloride process |
| JP6526209B2 (ja) | 2015-01-13 | 2019-06-05 | デ ルーカ オーブン テクノロジーズ、 エルエルシー | ワイヤメッシュ・ヒータ用の電気エネルギー伝達システム |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3341607A (en) * | 1965-12-16 | 1967-09-12 | Koppers Co Inc | Process for separation of monotertiary-butylated cresols |
| GB1241844A (en) * | 1968-08-23 | 1971-08-04 | Beecham Group Ltd | Penicillins |
| JPS5318515B2 (enExample) * | 1971-12-17 | 1978-06-15 |
-
1974
- 1974-06-19 US US480895A patent/US3925418A/en not_active Expired - Lifetime
-
1975
- 1975-06-16 NL NLAANVRAGE7507144,A patent/NL183030C/xx not_active IP Right Cessation
- 1975-06-16 IL IL47488A patent/IL47488A/xx unknown
- 1975-06-17 FR FR7518857A patent/FR2275445A1/fr active Granted
- 1975-06-19 GB GB2612975A patent/GB1466637A/en not_active Expired
- 1975-06-19 JP JP50073810A patent/JPS5858341B2/ja not_active Expired
- 1975-06-19 CH CH802075A patent/CH614189A5/xx not_active IP Right Cessation
- 1975-06-19 DE DE2527235A patent/DE2527235C2/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH614189A5 (enExample) | 1979-11-15 |
| FR2275445A1 (fr) | 1976-01-16 |
| NL183030C (nl) | 1988-07-01 |
| DE2527235A1 (de) | 1976-01-08 |
| NL7507144A (nl) | 1975-12-23 |
| IL47488A0 (en) | 1975-08-31 |
| NL183030B (nl) | 1988-02-01 |
| DE2527235C2 (de) | 1985-05-09 |
| US3925418A (en) | 1975-12-09 |
| IL47488A (en) | 1979-09-30 |
| FR2275445B1 (enExample) | 1978-09-01 |
| JPS5858341B2 (ja) | 1983-12-24 |
| JPS5119738A (enExample) | 1976-02-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19950618 |