GB1460377A - Antibacterial guanylhydrazones - Google Patents

Antibacterial guanylhydrazones

Info

Publication number
GB1460377A
GB1460377A GB4611174A GB4611174A GB1460377A GB 1460377 A GB1460377 A GB 1460377A GB 4611174 A GB4611174 A GB 4611174A GB 4611174 A GB4611174 A GB 4611174A GB 1460377 A GB1460377 A GB 1460377A
Authority
GB
United Kingdom
Prior art keywords
hydrogen
group
gram
guanylhydrazones
antibacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4611174A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of GB1460377A publication Critical patent/GB1460377A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB4611174A 1973-10-25 1974-10-24 Antibacterial guanylhydrazones Expired GB1460377A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP48120328A JPS5093989A (en:Method) 1973-10-25 1973-10-25

Publications (1)

Publication Number Publication Date
GB1460377A true GB1460377A (en) 1977-01-06

Family

ID=14783524

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4611174A Expired GB1460377A (en) 1973-10-25 1974-10-24 Antibacterial guanylhydrazones

Country Status (6)

Country Link
US (1) US3997528A (en:Method)
JP (1) JPS5093989A (en:Method)
CH (1) CH608809A5 (en:Method)
DE (1) DE2450618A1 (en:Method)
FR (1) FR2248845B1 (en:Method)
GB (1) GB1460377A (en:Method)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004007505A1 (en) * 2002-07-15 2004-01-22 Sandoz Ag Cephalosporins

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2620094A1 (de) * 1975-05-12 1976-12-02 Takeda Chemical Industries Ltd Cephalosporinverbindungen und verfahren zu ihrer herstellung
US4101658A (en) * 1975-06-04 1978-07-18 Shionogi & Co., Ltd. Antibacterial hydrazono cephalosporins
JPS5941999B2 (ja) * 1975-07-24 1984-10-11 武田薬品工業株式会社 セフエムまたはベナム化合物の製造法
JPS5946953B2 (ja) 1976-04-05 1984-11-15 三共株式会社 β−ラクタム化合物及びその製法
IL51092A0 (en) * 1976-12-10 1977-02-28 Abic Ltd Naphthyridine derivatives and their preparation
JPS53103493A (en) * 1977-02-18 1978-09-08 Takeda Chem Ind Ltd Cephalosporin derivatives and process for their preparation
EP0339496A3 (en) * 1988-04-26 1991-05-08 Ono Pharmaceutical Co., Ltd. Aminoguanidine derivatives
US5856474A (en) * 1994-04-25 1999-01-05 Biochemie Gesellschaft, M.B.H. Cephalosporin synthesis
AT402929B (de) * 1994-05-25 1997-09-25 Biochemie Gmbh Neue cephalosporinderivate, verfahren zu ihrer herstellung und ihre verwendung
AT402927B (de) * 1994-04-25 1997-09-25 Biochemie Gmbh Neue cefalosporinderivate, verfahren zu ihrer herstellung und ihre verwendung
RU2183212C2 (ru) * 1995-05-11 2002-06-10 Биохеми Гезельшафт Мбх Антибактериальные цефалоспорины, фармацевтическая композиция на их основе и способ лечения
US6693095B2 (en) * 1997-04-01 2004-02-17 Biochemie Gesellschaft M.B.H. Antibacterial substituted 7-acylamino-3-(methylhydrazono) methyl-cephalosporins and intermediates
CN113072567B (zh) * 2021-03-26 2022-10-14 海南海灵化学制药有限公司 一种拉氧头孢钠合成工艺

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH557381A (de) * 1967-04-15 1974-12-31 Fujisawa Pharmaceutical Co Verfahren zur herstellung von (delta)3-cephemverbindungen.
JPS5116436B1 (en:Method) * 1971-05-31 1976-05-24

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004007505A1 (en) * 2002-07-15 2004-01-22 Sandoz Ag Cephalosporins
US7485632B2 (en) 2002-07-15 2009-02-03 Nabriva Therapeutics Forschungs Gmbh Cephalosporins

Also Published As

Publication number Publication date
US3997528A (en) 1976-12-14
FR2248845A1 (en:Method) 1975-05-23
JPS5093989A (en:Method) 1975-07-26
FR2248845B1 (en:Method) 1977-11-04
DE2450618A1 (de) 1975-04-30
CH608809A5 (en) 1979-01-31

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee