GB1448181A - Phosphoric esters of cholestanol and epicholstanol - Google Patents
Phosphoric esters of cholestanol and epicholstanolInfo
- Publication number
- GB1448181A GB1448181A GB5449974A GB5449974A GB1448181A GB 1448181 A GB1448181 A GB 1448181A GB 5449974 A GB5449974 A GB 5449974A GB 5449974 A GB5449974 A GB 5449974A GB 1448181 A GB1448181 A GB 1448181A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cholestanol
- epicholestanol
- esters
- ion exchange
- product
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- QYIXCDOBOSTCEI-QCYZZNICSA-N (5alpha)-cholestan-3beta-ol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CCCC(C)C)[C@@]2(C)CC1 QYIXCDOBOSTCEI-QCYZZNICSA-N 0.000 title abstract 6
- QYIXCDOBOSTCEI-UHFFFAOYSA-N alpha-cholestanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 QYIXCDOBOSTCEI-UHFFFAOYSA-N 0.000 title abstract 5
- 150000002148 esters Chemical class 0.000 title abstract 5
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 241000282320 Panthera leo Species 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- -1 amino, morpholino, imidazolyl Chemical group 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000002102 aryl alkyloxo group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000005159 cyanoalkoxy group Chemical group 0.000 abstract 1
- 239000000551 dentifrice Substances 0.000 abstract 1
- ASMQGLCHMVWBQR-UHFFFAOYSA-M diphenyl phosphate Chemical compound C=1C=CC=CC=1OP(=O)([O-])OC1=CC=CC=C1 ASMQGLCHMVWBQR-UHFFFAOYSA-M 0.000 abstract 1
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000005342 ion exchange Methods 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- CMPQUABWPXYYSH-UHFFFAOYSA-N phenyl phosphate Chemical compound OP(O)(=O)OC1=CC=CC=C1 CMPQUABWPXYYSH-UHFFFAOYSA-N 0.000 abstract 1
- RLOWWWKZYUNIDI-UHFFFAOYSA-N phosphinic chloride Chemical group ClP=O RLOWWWKZYUNIDI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1176074A JPS537427B2 (https=) | 1974-01-30 | 1974-01-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1448181A true GB1448181A (en) | 1976-09-02 |
Family
ID=11786925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5449974A Expired GB1448181A (en) | 1974-01-30 | 1974-12-17 | Phosphoric esters of cholestanol and epicholstanol |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3974188A (https=) |
| JP (1) | JPS537427B2 (https=) |
| CA (1) | CA1035351A (https=) |
| CH (1) | CH606046A5 (https=) |
| DE (1) | DE2459985C3 (https=) |
| FR (1) | FR2282901A1 (https=) |
| GB (1) | GB1448181A (https=) |
| SE (1) | SE413247B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1553540A (en) * | 1977-02-23 | 1979-09-26 | Green Cross Corp | Medicaments containing cholesterol derivatives |
| EP0448697B1 (fr) * | 1989-10-13 | 1996-04-10 | Neurofit | Analogues de la vitamine a, leurs applications, notamment en tant que molecules cytotrophiques et cytoprotectrices, et compositions pharmaceutiques les contenant |
| FR2653117A1 (fr) * | 1989-10-13 | 1991-04-19 | Medafor | Derives des alcools gras a longue chaine, leurs applications, notamment en tant que molecules cytotrophiques et cytoprotectrices, et compositions pharmaceutiques les contenant. |
| KR20010043558A (ko) | 1998-05-13 | 2001-05-25 | 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 | 감수분열 조절 화합물 |
-
1974
- 1974-01-30 JP JP1176074A patent/JPS537427B2/ja not_active Expired
- 1974-12-12 FR FR7440921A patent/FR2282901A1/fr active Granted
- 1974-12-17 GB GB5449974A patent/GB1448181A/en not_active Expired
- 1974-12-18 DE DE2459985A patent/DE2459985C3/de not_active Expired
- 1974-12-18 US US05/533,834 patent/US3974188A/en not_active Expired - Lifetime
- 1974-12-20 CH CH1735274A patent/CH606046A5/xx not_active IP Right Cessation
- 1974-12-30 SE SE7416392A patent/SE413247B/xx unknown
-
1975
- 1975-01-14 CA CA217,880A patent/CA1035351A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2282901B1 (https=) | 1978-07-21 |
| CA1035351A (en) | 1978-07-25 |
| AU7696074A (en) | 1976-07-01 |
| DE2459985A1 (de) | 1975-08-14 |
| US3974188A (en) | 1976-08-10 |
| DE2459985B2 (de) | 1979-02-15 |
| SE7416392L (https=) | 1975-07-31 |
| JPS537427B2 (https=) | 1978-03-17 |
| JPS50105656A (https=) | 1975-08-20 |
| FR2282901A1 (fr) | 1976-03-26 |
| SE413247B (sv) | 1980-05-12 |
| DE2459985C3 (de) | 1979-10-31 |
| CH606046A5 (https=) | 1978-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |