ES8300735A1 - Un procedimiento para la preparacion de derivados de acidos fenil-alcanoicos. - Google Patents

Un procedimiento para la preparacion de derivados de acidos fenil-alcanoicos.

Info

Publication number
ES8300735A1
ES8300735A1 ES508806A ES508806A ES8300735A1 ES 8300735 A1 ES8300735 A1 ES 8300735A1 ES 508806 A ES508806 A ES 508806A ES 508806 A ES508806 A ES 508806A ES 8300735 A1 ES8300735 A1 ES 8300735A1
Authority
ES
Spain
Prior art keywords
formula
processes
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES508806A
Other languages
English (en)
Other versions
ES508806A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of ES508806A0 publication Critical patent/ES508806A0/es
Publication of ES8300735A1 publication Critical patent/ES8300735A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/40—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with ozone; by ozonolysis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86—Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE ACIDOS FENILALCANOICOS, DE FORMULA (I), EN LA QUE R ES HIDROGENO, ALQUILO INFERIOR O ACILO; R ES ALCANONITRILO O ALQUENO INFERIOR-TRIILO; R ES ALQUILO; X ES O, S, SO O SO ; Y R PUEDE SER VARIOS RADICALES CONSISTE EN LA REACCION DE UM COMPUESTO DE FORMULA (II), EN LA R'' ES ALQUILENO O ALQUENILENO INFERIOR, Y R , R Y X TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), CON DIALQUILCARBONATO, EN PRESENCIA DE UNA BASE; SEGUIDA DE HIDROLISIS DEL PRODUCTO RESULTANTE; DESCARBOXILACION Y TRATAMIENTO CON UN ACILO O SU EQUIVALENTE REACTIVO. >ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS ACTIVIDADES ANTIINFLAMATORIAS, ANALGESICAS Y ANTIPIRETICAS.
ES508806A 1980-01-28 1982-01-15 Un procedimiento para la preparacion de derivados de acidos fenil-alcanoicos. Expired ES8300735A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8002790 1980-01-28
GB8039308 1980-12-08

Publications (2)

Publication Number Publication Date
ES508806A0 ES508806A0 (es) 1982-11-16
ES8300735A1 true ES8300735A1 (es) 1982-11-16

Family

ID=26274313

Family Applications (2)

Application Number Title Priority Date Filing Date
ES508806A Expired ES8300735A1 (es) 1980-01-28 1982-01-15 Un procedimiento para la preparacion de derivados de acidos fenil-alcanoicos.
ES82508805A Granted ES508805A0 (es) 1980-01-28 1982-01-15 Un procedimiento para la preparacion de derivados de acidos fenil-alcanoicos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES82508805A Granted ES508805A0 (es) 1980-01-28 1982-01-15 Un procedimiento para la preparacion de derivados de acidos fenil-alcanoicos.

Country Status (10)

Country Link
US (1) US4367238A (es)
EP (1) EP0033614B1 (es)
AR (1) AR228586A1 (es)
AT (1) ATE7782T1 (es)
AU (1) AU537560B2 (es)
CA (1) CA1195691A (es)
DE (1) DE3162626D1 (es)
DK (1) DK34781A (es)
ES (2) ES8300735A1 (es)
GR (1) GR73505B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3110009A1 (de) * 1981-03-11 1982-09-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue benzofuran-derivate, ihre herstellung und verwendung
US4857455A (en) * 1982-11-26 1989-08-15 Syntex (U.S.A) Inc. Method for the determination of peroxidase using fluorogenic substrates
GB8328253D0 (en) * 1983-10-21 1983-11-23 Shell Int Research Substituted azetidine derivatives
US4911754A (en) * 1987-07-16 1990-03-27 American Cyanamid Company Herbicidally active aryloxy saturated 5-membered benzo fused hetero-cyclic compounds
US6001877A (en) * 1989-06-27 1999-12-14 Ono Pharmaceutical Co., Ltd. Phenylalkan(en)oic acid
US5256686A (en) * 1989-06-27 1993-10-26 Ono Pharmaceutical Co., Ltd. Phenylalkan(en)oic acid
ES2163986B1 (es) * 1999-07-13 2003-02-16 Menarini Lab Acidos-alfa-arilpropionicos y arilaceticos como inhibidores de la ciclooxigenasa-ii.
CN1414942A (zh) * 2000-01-04 2003-04-30 韩国化学研究院 2－苯基链烷酸衍生物的制备方法
EP1366763A1 (en) * 2002-05-28 2003-12-03 Ciba SC Holding AG Hydroxy diphenyl ether compounds as anti-inflammatory agents
EP1481959A1 (de) * 2003-05-22 2004-12-01 DSM Fine Chemicals Austria Nfg GmbH & Co KG Verfahren zur Herstellung von Lactonen und von aromatischen Hydroxycarbonsäuren
GB201118876D0 (en) * 2011-11-01 2011-12-14 Astex Therapeutics Ltd Pharmaceutical compounds
EP3816155A1 (en) * 2013-08-23 2021-05-05 Virginia Commonwealth University Ester nitrates derivatives of aromatic aldehydes with multiple pharmalogic properties to treat sickle cell disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2838522A (en) * 1956-04-30 1958-06-10 Dow Chemical Co Phthalides
SE363818B (es) * 1968-08-15 1974-02-04 Lilly Co Eli
US4120871A (en) * 1975-05-06 1978-10-17 Fisons Limited 5-Organosulfonyl, 5-organosulfinyl or 5-haloalkanoyl-benzofuran-2-ones

Also Published As

Publication number Publication date
ES8300734A1 (es) 1982-11-16
ATE7782T1 (de) 1984-06-15
CA1195691A (en) 1985-10-22
ES508806A0 (es) 1982-11-16
EP0033614B1 (en) 1984-06-06
AR228586A1 (es) 1983-03-30
US4367238A (en) 1983-01-04
AU6668781A (en) 1981-08-06
DK34781A (da) 1981-07-29
ES508805A0 (es) 1982-11-16
EP0033614A1 (en) 1981-08-12
DE3162626D1 (en) 1984-07-12
GR73505B (es) 1984-03-06
AU537560B2 (en) 1984-06-28

Similar Documents

Publication Publication Date Title
ES8301925A1 (es) Un procedimiento para la obtencion de un derivado acilico sustituido del compuesto acido 1,2,3,4-tetrahidro-3-isoqui- nolein-carboxilico
ES8301876A1 (es) Un procedimiento para preparar esteres piretroides de 1,1'-bifenil-3-ilmetilo.
ES8800272A1 (es) Un procedimiento para la preparacion de polipeptidos.
ES8300735A1 (es) Un procedimiento para la preparacion de derivados de acidos fenil-alcanoicos.
ES8704153A1 (es) Un procedimiento para preparar derivados de pirimidina
JPS5781411A (en) Medicinal composition having antiviral action
JPS5227721A (en) Process for preparation of substituted phosphonic acid derivatives
JPS56103168A (en) Thiazole derivative, its preparation, and antihistaminic agent containing the same
IL75116A (en) Ethyl substituted-beta-carboxylates,process for the preparation thereof and pharmaceutical compositions containing the same
ES8106482A1 (es) Un procedimiento para la preparacion de nuevos acidos feni- lalcanoicos
JPS5455565A (en) Novel thiazolidine derivative
ATE56707T1 (de) Imidazolverbindungen, verfahren zu deren herstellung und deren pharmazeutische zusammensetzungen.
JPS57118555A (en) Leucotriene-analog compound, its preparation, and leucotriene-biosynthesis inhibiting agent containing said compound as active component
SE8207480D0 (sv) New bicyclic compounds and a process for the preparation thereof
JPS55151555A (en) Proline derivatives and their production
JPS5455544A (en) Pheylacetamide derivatives
JPS5699480A (en) Preparation of pyridopyrimidine derivative
JPS5427546A (en) Liquid crystal compound
JPS55129265A (en) Interferon-inducing agent
JPS5592363A (en) New 2-azetidinone derivative
JPS55108883A (en) Ethyl-(gamma-acetamino-gamma-ethoxycarbonyl-gamma-cyanopropyl- methyl) phosphinate and its preparation
ES8500227A1 (es) Procedimiento para la preparacion de alquileteres de acido 1-alquil- o 1,4-dialquil-1h--pirrol-2-acetico.
JPS56125385A (en) Novel piperidine derivative
JPS56127378A (en) 2-alkoxyindolizine derivative and its preparation
JPS5759848A (en) Cyclohexanecarboxylic acid derivative