GB1433593A - Conjugates - Google Patents
ConjugatesInfo
- Publication number
- GB1433593A GB1433593A GB2704872A GB2704872A GB1433593A GB 1433593 A GB1433593 A GB 1433593A GB 2704872 A GB2704872 A GB 2704872A GB 2704872 A GB2704872 A GB 2704872A GB 1433593 A GB1433593 A GB 1433593A
- Authority
- GB
- United Kingdom
- Prior art keywords
- lectin
- therapeutic agent
- conjugates
- june
- enzyme
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 102000004856 Lectins Human genes 0.000 abstract 5
- 108090001090 Lectins Proteins 0.000 abstract 5
- 239000002523 lectin Substances 0.000 abstract 5
- 239000003814 drug Substances 0.000 abstract 3
- 229940124597 therapeutic agent Drugs 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- REYLLNRLWCBKCM-YFKPBYRVSA-N (2s)-2-acetamido-4-sulfanylbutanoic acid Chemical compound CC(=O)N[C@H](C(O)=O)CCS REYLLNRLWCBKCM-YFKPBYRVSA-N 0.000 abstract 1
- HBOMLICNUCNMMY-KJFJCRTCSA-N 1-[(4s,5s)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Chemical compound O=C1NC(=O)C(C)=CN1C1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-KJFJCRTCSA-N 0.000 abstract 1
- JRBJSXQPQWSCCF-UHFFFAOYSA-N 3,3'-Dimethoxybenzidine Chemical compound C1=C(N)C(OC)=CC(C=2C=C(OC)C(N)=CC=2)=C1 JRBJSXQPQWSCCF-UHFFFAOYSA-N 0.000 abstract 1
- OROGUZVNAFJPHA-UHFFFAOYSA-N 3-hydroxy-2,4-dimethyl-2H-thiophen-5-one Chemical compound CC1SC(=O)C(C)=C1O OROGUZVNAFJPHA-UHFFFAOYSA-N 0.000 abstract 1
- ZKZNWRUUTQNYTH-UHFFFAOYSA-N 4-azidobenzenesulfonic acid Chemical compound OS(=O)(=O)C1=CC=C(N=[N+]=[N-])C=C1 ZKZNWRUUTQNYTH-UHFFFAOYSA-N 0.000 abstract 1
- 239000004382 Amylase Substances 0.000 abstract 1
- 108010065511 Amylases Proteins 0.000 abstract 1
- 102000013142 Amylases Human genes 0.000 abstract 1
- 108010001478 Bacitracin Proteins 0.000 abstract 1
- 102000016938 Catalase Human genes 0.000 abstract 1
- 108010053835 Catalase Proteins 0.000 abstract 1
- 208000002064 Dental Plaque Diseases 0.000 abstract 1
- 108010001682 Dextranase Proteins 0.000 abstract 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 abstract 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 abstract 1
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 abstract 1
- 102000007562 Serum Albumin Human genes 0.000 abstract 1
- 108010071390 Serum Albumin Proteins 0.000 abstract 1
- 208000014151 Stomatognathic disease Diseases 0.000 abstract 1
- 229960004308 acetylcysteine Drugs 0.000 abstract 1
- 229960000723 ampicillin Drugs 0.000 abstract 1
- AVKUERGKIZMTKX-NJBDSQKTSA-N ampicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=CC=C1 AVKUERGKIZMTKX-NJBDSQKTSA-N 0.000 abstract 1
- 235000019418 amylase Nutrition 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229960003071 bacitracin Drugs 0.000 abstract 1
- 229930184125 bacitracin Natural products 0.000 abstract 1
- CLKOFPXJLQSYAH-ABRJDSQDSA-N bacitracin A Chemical compound C1SC([C@@H](N)[C@@H](C)CC)=N[C@@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]1C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2N=CNC=2)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC1 CLKOFPXJLQSYAH-ABRJDSQDSA-N 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 230000001268 conjugating effect Effects 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 239000007822 coupling agent Substances 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 239000012954 diazonium Substances 0.000 abstract 1
- 150000001989 diazonium salts Chemical class 0.000 abstract 1
- -1 e.g. a dextranose Proteins 0.000 abstract 1
- 229960003276 erythromycin Drugs 0.000 abstract 1
- 108010005131 levanase Proteins 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 235000018102 proteins Nutrition 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- DVKJHBMWWAPEIU-UHFFFAOYSA-N toluene 2,4-diisocyanate Chemical compound CC1=CC=C(N=C=O)C=C1N=C=O DVKJHBMWWAPEIU-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/57—Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Birds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2704872A GB1433593A (en) | 1972-06-09 | 1972-06-09 | Conjugates |
| ZA733745A ZA733745B (en) | 1972-06-09 | 1973-06-04 | Oral preparations |
| IE899/73A IE37742B1 (en) | 1972-06-09 | 1973-06-06 | Conjugates |
| AU56594/73A AU5659473A (en) | 1972-06-09 | 1973-06-06 | Anti-caries compound anti-caries compound |
| IL42462A IL42462A0 (en) | 1972-06-09 | 1973-06-07 | Oral preparations |
| NL7307927A NL7307927A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-06-09 | 1973-06-07 | |
| US05/367,892 US3952092A (en) | 1972-06-09 | 1973-06-07 | Oral preparations |
| DE2329253A DE2329253A1 (de) | 1972-06-09 | 1973-06-08 | Mundpraeparat |
| IT50561/73A IT1078724B (it) | 1972-06-09 | 1973-06-08 | Preparati di uso stomatologico per prevenire l'insorgere di malattie nel cavo orale comprendenti almeno un'agglutina associata ad una molecola niologicamente attiva |
| BE132080A BE800695A (fr) | 1972-06-09 | 1973-06-08 | Preparations pharmaceutiques a administrer par voie orale contenant de l'agglutinine |
| ES415753A ES415753A1 (es) | 1972-06-09 | 1973-06-09 | Procedimiento de obtencion de composiciones basadas en mo- leculas biologicamente activas para combatir caries dentalesy enfermedades periodontales. |
| FR7321285A FR2187294B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-06-09 | 1973-06-12 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2704872A GB1433593A (en) | 1972-06-09 | 1972-06-09 | Conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1433593A true GB1433593A (en) | 1976-04-28 |
Family
ID=10253320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2704872A Expired GB1433593A (en) | 1972-06-09 | 1972-06-09 | Conjugates |
Country Status (12)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4217341A (en) * | 1977-12-07 | 1980-08-12 | The University of Louisville | Composition and method for inhibiting the adherence of dental plaque-producing bacteria to smooth surfaces |
| US5851527A (en) * | 1988-04-18 | 1998-12-22 | Immunomedics, Inc. | Method for antibody targeting of therapeutic agents |
| SE461570B (sv) * | 1988-06-06 | 1990-03-05 | Rama Bio Link Ab | Farmaceutiskt preparat och konjugat av en baktericid och en antikropp |
| AU642979B2 (en) * | 1990-03-21 | 1993-11-04 | Quest International B.V. | Utilization and delivery of enzymes |
| AU641736B2 (en) * | 1990-03-21 | 1993-09-30 | Quest International B.V. | Delivery of agents |
| JP2873256B2 (ja) * | 1991-02-01 | 1999-03-24 | シャープ 株式会社 | 液晶表示装置 |
| KR19980075132A (ko) * | 1997-03-28 | 1998-11-05 | 민병무 | 중간사슬지방산(medium-chain fatty acids)을 유효성분으로 하는 치아우식증 및 치주질환 치료제용 의약조성물 |
| US5871714A (en) * | 1997-10-16 | 1999-02-16 | Pharmacal Biotechnologies, Inc. | Compositions for controlling bacterial colonization |
| US5972311A (en) * | 1998-01-26 | 1999-10-26 | Duke University | Method of preventing dental caries and other oral lesions |
| WO2000047175A1 (en) * | 1999-02-12 | 2000-08-17 | Pharmacal Biotechnologies, Llc | Oral compositions and methods of production thereof |
| US6447754B1 (en) | 2000-01-24 | 2002-09-10 | Akpharma Inc. | Oral rinse methods and compositions |
| US20020064550A1 (en) * | 2000-09-07 | 2002-05-30 | Akpharma, Inc. | Edible candy compositions and methods of using same |
| US20020099037A1 (en) * | 2001-01-19 | 2002-07-25 | Akpharma, Inc. | Method for alleviating syndromes and conditions of discomfort of the mammalian intestinal and genito-urinary tracts |
| GB2555391B (en) * | 2016-10-21 | 2019-06-26 | Algipharma As | Bacitracin-alginate oligomer conjugates |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3538230A (en) * | 1966-12-05 | 1970-11-03 | Lever Brothers Ltd | Oral compositions containing silica xerogels as cleaning and polishing agents |
| DE1617886A1 (de) * | 1967-03-06 | 1971-01-28 | Dr Med Karl Theurer | Verfahren zur Herstellung von Arzneimitteln mit selektivem Tropismus gegen Krebs und bestimmte Organe |
-
1972
- 1972-06-09 GB GB2704872A patent/GB1433593A/en not_active Expired
-
1973
- 1973-06-04 ZA ZA733745A patent/ZA733745B/xx unknown
- 1973-06-06 IE IE899/73A patent/IE37742B1/xx unknown
- 1973-06-06 AU AU56594/73A patent/AU5659473A/en not_active Expired
- 1973-06-07 NL NL7307927A patent/NL7307927A/xx unknown
- 1973-06-07 US US05/367,892 patent/US3952092A/en not_active Expired - Lifetime
- 1973-06-07 IL IL42462A patent/IL42462A0/xx unknown
- 1973-06-08 IT IT50561/73A patent/IT1078724B/it active
- 1973-06-08 DE DE2329253A patent/DE2329253A1/de active Pending
- 1973-06-08 BE BE132080A patent/BE800695A/xx unknown
- 1973-06-09 ES ES415753A patent/ES415753A1/es not_active Expired
- 1973-06-12 FR FR7321285A patent/FR2187294B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3952092A (en) | 1976-04-20 |
| IL42462A0 (en) | 1973-08-29 |
| IT1078724B (it) | 1985-05-08 |
| IE37742L (en) | 1973-12-09 |
| AU5659473A (en) | 1974-12-12 |
| ZA733745B (en) | 1974-04-24 |
| BE800695A (fr) | 1973-12-10 |
| FR2187294A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-01-18 |
| FR2187294B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-12-31 |
| ES415753A1 (es) | 1976-06-16 |
| NL7307927A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-12-11 |
| IE37742B1 (en) | 1977-09-28 |
| DE2329253A1 (de) | 1973-12-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |