GB1433308A - Acetamidophenyl esters of salicylic acid derivatives - Google Patents
Acetamidophenyl esters of salicylic acid derivativesInfo
- Publication number
- GB1433308A GB1433308A GB3115974A GB3115974A GB1433308A GB 1433308 A GB1433308 A GB 1433308A GB 3115974 A GB3115974 A GB 3115974A GB 3115974 A GB3115974 A GB 3115974A GB 1433308 A GB1433308 A GB 1433308A
- Authority
- GB
- United Kingdom
- Prior art keywords
- benzyl
- compounds
- esters
- acid derivatives
- propionyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Acetamidophenyl esters Chemical class 0.000 title 1
- 229940058287 salicylic acid derivative anticestodals Drugs 0.000 title 1
- 150000003872 salicylic acid derivatives Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 7
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 4
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000001501 propionyl group Chemical group O=C([*])C([H])([H])C([H])([H])[H] 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000001462 1-pyrrolyl group Chemical group [*]N1C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- QOSSAOTZNIDXMA-UHFFFAOYSA-N Dicylcohexylcarbodiimide Chemical compound C1CCCCC1N=C=NC1CCCCC1 QOSSAOTZNIDXMA-UHFFFAOYSA-N 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 230000032050 esterification Effects 0.000 abstract 1
- 238000005886 esterification reaction Methods 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000000168 pyrrolyl group Chemical group 0.000 abstract 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical class OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US381123A US3892769A (en) | 1973-07-20 | 1973-07-20 | Acetaminophen esters of aryl salicylic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1433308A true GB1433308A (en) | 1976-04-28 |
Family
ID=23503778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3115974A Expired GB1433308A (en) | 1973-07-20 | 1974-07-15 | Acetamidophenyl esters of salicylic acid derivatives |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3892769A (en, 2012) |
| JP (1) | JPS5041841A (en, 2012) |
| CH (1) | CH605663A5 (en, 2012) |
| DE (1) | DE2434929C2 (en, 2012) |
| DK (1) | DK359074A (en, 2012) |
| FR (1) | FR2237623B1 (en, 2012) |
| GB (1) | GB1433308A (en, 2012) |
| NL (1) | NL7408859A (en, 2012) |
| SE (1) | SE411116B (en, 2012) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0017102A1 (en) * | 1979-03-22 | 1980-10-15 | Merck & Co. Inc. | Composition containing a phenyl benzoic acid compound and acetaminophen combination for the treatment of pain and inflammation and process for preparing the same |
| JPS57158922A (en) * | 1981-03-27 | 1982-09-30 | Hitachi Ltd | Method for forming fluorescent screen of color picture tube |
| IT1203656B (it) * | 1983-06-10 | 1989-02-15 | Medosan Ind Biochimi | Attivita' antiaggregante piastrinica,antiinfiammatoria e broncolitica di esteri aroilpirrol e pirrilfenil acetici delle 7 (w-ossialchil) teofilline |
| FR2704146B1 (fr) * | 1993-04-19 | 1995-07-13 | Cripdom | Microcapsules d'acide acétylsalicylique à libération contrôlée. |
| FR2830447B1 (fr) * | 2001-10-09 | 2004-04-16 | Flamel Tech Sa | Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques |
| US8101209B2 (en) | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
| ES2320438T7 (es) | 2002-04-09 | 2013-02-14 | Flamel Technologies | Formulación farmaceútica oral de suspensión acuosa de microcápsulas que permiten la liberación modificada de principio(s) activo(s) |
| EP1492531B3 (fr) * | 2002-04-09 | 2012-04-11 | Flamel Technologies | Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiée d'amoxicilline |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3427305A (en) * | 1966-11-01 | 1969-02-11 | Searle & Co | 5 - ((halo/alkoxy)phenyl) - 1 - (p - sulfonamido(phenyl/benzyl)) - 2 - pyrrolepropionic acids |
-
1973
- 1973-07-20 US US381123A patent/US3892769A/en not_active Expired - Lifetime
-
1974
- 1974-07-01 SE SE7408642A patent/SE411116B/xx not_active IP Right Cessation
- 1974-07-01 NL NL7408859A patent/NL7408859A/xx not_active Application Discontinuation
- 1974-07-04 DK DK359074A patent/DK359074A/da unknown
- 1974-07-15 GB GB3115974A patent/GB1433308A/en not_active Expired
- 1974-07-18 FR FR7425021A patent/FR2237623B1/fr not_active Expired
- 1974-07-18 CH CH993374A patent/CH605663A5/xx not_active IP Right Cessation
- 1974-07-19 DE DE2434929A patent/DE2434929C2/de not_active Expired
- 1974-07-20 JP JP49082763A patent/JPS5041841A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| SE411116B (sv) | 1979-12-03 |
| DE2434929C2 (de) | 1984-09-13 |
| JPS5041841A (en, 2012) | 1975-04-16 |
| CH605663A5 (en, 2012) | 1978-10-13 |
| SE7408642L (en, 2012) | 1975-01-21 |
| US3892769A (en) | 1975-07-01 |
| NL7408859A (nl) | 1975-01-22 |
| DK359074A (en, 2012) | 1975-03-10 |
| DE2434929A1 (de) | 1975-02-06 |
| FR2237623A1 (en, 2012) | 1975-02-14 |
| FR2237623B1 (en, 2012) | 1977-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |