GB1480591A - Substituted phthalazines and their use as therapeutic agents - Google Patents

Substituted phthalazines and their use as therapeutic agents

Info

Publication number
GB1480591A
GB1480591A GB50623/73A GB5062373A GB1480591A GB 1480591 A GB1480591 A GB 1480591A GB 50623/73 A GB50623/73 A GB 50623/73A GB 5062373 A GB5062373 A GB 5062373A GB 1480591 A GB1480591 A GB 1480591A
Authority
GB
United Kingdom
Prior art keywords
substituted
therapeutic agents
oct
hydrogen
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB50623/73A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Co PLC
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co PLC filed Critical Boots Co PLC
Priority to GB50623/73A priority Critical patent/GB1480591A/en
Priority to DK229774A priority patent/DK229774A/da
Priority to FI1343/74A priority patent/FI134374A/fi
Priority to SE7405964A priority patent/SE7405964L/xx
Priority to NO741603A priority patent/NO741603L/no
Priority to IL45875A priority patent/IL45875A/en
Priority to AU74484/74A priority patent/AU491398B2/en
Priority to ZA00746761A priority patent/ZA746761B/en
Priority to DE19742451117 priority patent/DE2451117A1/en
Priority to CY952A priority patent/CY952A/en
Priority to HU74BO00001522A priority patent/HU171553B/en
Priority to RO7480359A priority patent/RO69058A/en
Priority to LU71199A priority patent/LU71199A1/xx
Priority to CS747406A priority patent/CS188931B2/en
Priority to CH1453274A priority patent/CH608493A5/xx
Priority to ES431524A priority patent/ES431524A2/en
Priority to JP12531674A priority patent/JPS5077382A/ja
Priority to AT873074A priority patent/AT346849B/en
Priority to BE150131A priority patent/BE821763R/en
Priority to PH16477A priority patent/PH10816A/en
Priority to NL7414229A priority patent/NL7414229A/en
Priority to FR7436390A priority patent/FR2249671A2/en
Priority to DD18207774A priority patent/DD116140A6/xx
Priority to BG028086A priority patent/BG25083A3/en
Priority to IE2248/74A priority patent/IE40536B1/en
Priority to SU742077860A priority patent/SU656516A3/en
Priority to CA212,785A priority patent/CA1032163A/en
Publication of GB1480591A publication Critical patent/GB1480591A/en
Priority to US05/820,907 priority patent/US4120960A/en
Priority to HK557/78A priority patent/HK55778A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1480591 Substituted phthalazines BOOTS CO Ltd 28 Oct 1974 [31 Oct 1973] 50623/73 Heading C2C The invention comprises compounds of the formula or their enol or enthiol forms of formula in which Q is COOH, CH 2 OH or COOR 6 wherein R 6 is an ester forming group; X is oxygen or sulphur; R is hydrogen or alkyl; Z is hydrogen or acyl; Ar is an aryl group unsubstituted in the positions ortho to the point of attachment to the phthalazine ring and the ring J is substituted, or a pharmaceutically acceptable salt with an inorganic or organic base of any compound which is an acid. The compounds of the invention are used as therapeutic agents.
GB50623/73A 1973-10-31 1973-10-31 Substituted phthalazines and their use as therapeutic agents Expired GB1480591A (en)

Priority Applications (29)

Application Number Priority Date Filing Date Title
GB50623/73A GB1480591A (en) 1973-10-31 1973-10-31 Substituted phthalazines and their use as therapeutic agents
DK229774A DK229774A (en) 1973-10-31 1974-04-26
FI1343/74A FI134374A (en) 1973-10-31 1974-05-02
SE7405964A SE7405964L (en) 1973-10-31 1974-05-03
NO741603A NO741603L (en) 1973-10-31 1974-05-03
IL45875A IL45875A (en) 1973-10-31 1974-10-18 1,2-dihydro- or 1,2,3,4-tetrahydro-phthalazines and diuretic and saluretic compositions containing them
AU74484/74A AU491398B2 (en) 1973-10-31 1974-10-18 Hydrophalazine dertivatives and therapeutic compositions containing same
ZA00746761A ZA746761B (en) 1973-10-31 1974-10-24 Therapeutic agents
DE19742451117 DE2451117A1 (en) 1973-10-31 1974-10-28 THERAPEUTICALLY EFFECTIVE COMPOUNDS
CY952A CY952A (en) 1973-10-31 1974-10-28 Substituted phthalazines and their use of therapeutic agents
HU74BO00001522A HU171553B (en) 1973-10-31 1974-10-29 Process for preparing derivatives of phtalazine
RO7480359A RO69058A (en) 1973-10-31 1974-10-29 PROCESS FOR THE PREPARATION OF FTALASINE DERIVATIVES
LU71199A LU71199A1 (en) 1973-10-31 1974-10-29
ES431524A ES431524A2 (en) 1973-10-31 1974-10-30 A procedure for preparing ftalazine derivatives. (Machine-translation by Google Translate, not legally binding)
CH1453274A CH608493A5 (en) 1973-10-31 1974-10-30
CS747406A CS188931B2 (en) 1973-10-31 1974-10-30 Method of producing phtalazine derivatives
JP12531674A JPS5077382A (en) 1973-10-31 1974-10-30
AT873074A AT346849B (en) 1973-10-31 1974-10-30 METHOD FOR PRODUCING NEW PHTHALAZINE DERIVATIVES AND THEIR SALTS AND THEIR OPTICAL ISOMERS
DD18207774A DD116140A6 (en) 1973-10-31 1974-10-31
PH16477A PH10816A (en) 1973-10-31 1974-10-31 4-substituted-2-aryl-1,2-dihydrophthalazine-1-acetic acid derivatives,compositions thereof and method of use
NL7414229A NL7414229A (en) 1973-10-31 1974-10-31 PROCESS FOR THE PREPARATION OF PHTHALAZINE EDERI
FR7436390A FR2249671A2 (en) 1973-10-31 1974-10-31 2-Aryl-4poxo-phthalazin-2-ones and their enols - as diuretics and saluretics also 2-sulpho-1-naphthols as inters therefor
BE150131A BE821763R (en) 1973-10-31 1974-10-31 THERAPEUTIC COMPOSITIONS
BG028086A BG25083A3 (en) 1973-10-31 1974-10-31 A method of obtaining phtalazine derivatives
IE2248/74A IE40536B1 (en) 1973-10-31 1974-10-31 Substituted phthalazines and their use as therapeutic agents
SU742077860A SU656516A3 (en) 1973-10-31 1974-10-31 Method of obtaining derivatives of phthalazine
CA212,785A CA1032163A (en) 1973-10-31 1974-10-31 1,2-dihydrophthalazine-1-acetic acids
US05/820,907 US4120960A (en) 1973-10-31 1977-08-01 Therapeutic agents
HK557/78A HK55778A (en) 1973-10-31 1978-09-21 Substituted phthalazines and their use as therapeutic agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB50623/73A GB1480591A (en) 1973-10-31 1973-10-31 Substituted phthalazines and their use as therapeutic agents

Publications (1)

Publication Number Publication Date
GB1480591A true GB1480591A (en) 1977-07-20

Family

ID=10456665

Family Applications (1)

Application Number Title Priority Date Filing Date
GB50623/73A Expired GB1480591A (en) 1973-10-31 1973-10-31 Substituted phthalazines and their use as therapeutic agents

Country Status (13)

Country Link
AT (1) AT346849B (en)
BE (1) BE821763R (en)
CS (1) CS188931B2 (en)
CY (1) CY952A (en)
DK (1) DK229774A (en)
FI (1) FI134374A (en)
GB (1) GB1480591A (en)
HK (1) HK55778A (en)
HU (1) HU171553B (en)
NO (1) NO741603L (en)
SE (1) SE7405964L (en)
SU (1) SU656516A3 (en)
ZA (1) ZA746761B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001072305A1 (en) * 2000-03-28 2001-10-04 Ramazanov, Ziadin Magomedovich A medicament and method for the production thereof

Also Published As

Publication number Publication date
CS188931B2 (en) 1979-03-30
CY952A (en) 1978-12-22
AT346849B (en) 1978-11-27
DK229774A (en) 1975-06-23
SE7405964L (en) 1975-05-02
BE821763R (en) 1975-04-30
NO741603L (en) 1975-05-26
FI134374A (en) 1975-05-01
ATA873074A (en) 1978-04-15
SU656516A3 (en) 1979-04-05
ZA746761B (en) 1975-11-26
HU171553B (en) 1978-02-28
HK55778A (en) 1978-09-29

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee