GB1430842A - Method of producing l-lysine by fermentation - Google Patents
Method of producing l-lysine by fermentationInfo
- Publication number
- GB1430842A GB1430842A GB2014973A GB2014973A GB1430842A GB 1430842 A GB1430842 A GB 1430842A GB 2014973 A GB2014973 A GB 2014973A GB 2014973 A GB2014973 A GB 2014973A GB 1430842 A GB1430842 A GB 1430842A
- Authority
- GB
- United Kingdom
- Prior art keywords
- lysine
- april
- strain
- fermentation
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 title abstract 10
- 238000000855 fermentation Methods 0.000 title abstract 2
- 230000004151 fermentation Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 239000004472 Lysine Substances 0.000 abstract 5
- 235000019766 L-Lysine Nutrition 0.000 abstract 4
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 abstract 2
- FDGQSTZJBFJUBT-UHFFFAOYSA-N hypoxanthine Chemical compound O=C1NC=NC2=C1NC=N2 FDGQSTZJBFJUBT-UHFFFAOYSA-N 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000186146 Brevibacterium Species 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 abstract 1
- 241000186216 Corynebacterium Species 0.000 abstract 1
- UGQMRVRMYYASKQ-UHFFFAOYSA-N Hypoxanthine nucleoside Natural products OC1C(O)C(CO)OC1N1C(NC=NC2=O)=C2N=C1 UGQMRVRMYYASKQ-UHFFFAOYSA-N 0.000 abstract 1
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 abstract 1
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 abstract 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- JZRWCGZRTZMZEH-UHFFFAOYSA-N Thiamine Natural products CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 abstract 1
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 abstract 1
- 235000004279 alanine Nutrition 0.000 abstract 1
- 229960003767 alanine Drugs 0.000 abstract 1
- 235000019728 animal nutrition Nutrition 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- FDJOLVPMNUYSCM-UVKKECPRSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7, Chemical compound [Co+3].N#[C-].C1([C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)[N-]\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O FDJOLVPMNUYSCM-UVKKECPRSA-L 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- NSNHWTBQMQIDCF-UHFFFAOYSA-N dihydrate;hydrochloride Chemical compound O.O.Cl NSNHWTBQMQIDCF-UHFFFAOYSA-N 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 235000018977 lysine Nutrition 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 235000021048 nutrient requirements Nutrition 0.000 abstract 1
- 229940055726 pantothenic acid Drugs 0.000 abstract 1
- 235000019161 pantothenic acid Nutrition 0.000 abstract 1
- 239000011713 pantothenic acid Substances 0.000 abstract 1
- 229960002429 proline Drugs 0.000 abstract 1
- 235000013930 proline Nutrition 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229960001153 serine Drugs 0.000 abstract 1
- 235000004400 serine Nutrition 0.000 abstract 1
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 abstract 1
- 229960003495 thiamine Drugs 0.000 abstract 1
- 235000019157 thiamine Nutrition 0.000 abstract 1
- 239000011721 thiamine Substances 0.000 abstract 1
- 229940045999 vitamin b 12 Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP47042527A JPS491794A (enrdf_load_stackoverflow) | 1972-04-27 | 1972-04-27 | |
| JP8264172A JPS4936888A (enrdf_load_stackoverflow) | 1972-08-18 | 1972-08-18 | |
| JP9403072A JPS561078B2 (enrdf_load_stackoverflow) | 1972-09-19 | 1972-09-19 | |
| JP12024772A JPS551040B2 (enrdf_load_stackoverflow) | 1972-11-30 | 1972-11-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1430842A true GB1430842A (en) | 1976-04-07 |
Family
ID=27461211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2014973A Expired GB1430842A (en) | 1972-04-27 | 1973-04-27 | Method of producing l-lysine by fermentation |
Country Status (11)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1916308A1 (en) * | 2006-10-26 | 2008-04-30 | DSMIP Assets B.V. | Use of vitamins in fermentation processes for the production of amino acids |
| CN110885863A (zh) * | 2019-12-01 | 2020-03-17 | 齐齐哈尔龙江阜丰生物科技有限公司 | 利用菌体蛋白制备赖氨酸发酵培养基的方法 |
-
1973
- 1973-04-24 CS CS293173A patent/CS182785B2/cs unknown
- 1973-04-24 SE SE7305740A patent/SE410978B/xx unknown
- 1973-04-26 DK DK228973A patent/DK134570B/da not_active IP Right Cessation
- 1973-04-26 NL NL7305828A patent/NL175197C/xx not_active IP Right Cessation
- 1973-04-26 SU SU1912978A patent/SU526295A3/ru active
- 1973-04-26 CH CH600873A patent/CH574501A5/xx not_active IP Right Cessation
- 1973-04-26 BG BG023447A patent/BG24960A3/xx unknown
- 1973-04-26 HU HUAI000226 patent/HU172604B/hu unknown
- 1973-04-27 FR FR7315472A patent/FR2182211B1/fr not_active Expired
- 1973-04-27 CA CA170,007A patent/CA995163A/en not_active Expired
- 1973-04-27 GB GB2014973A patent/GB1430842A/en not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1916308A1 (en) * | 2006-10-26 | 2008-04-30 | DSMIP Assets B.V. | Use of vitamins in fermentation processes for the production of amino acids |
| WO2008049615A1 (en) * | 2006-10-26 | 2008-05-02 | Dsm Ip Assets B.V. | Use of vitamins in fermentation processes for the production of amino acids |
| CN110885863A (zh) * | 2019-12-01 | 2020-03-17 | 齐齐哈尔龙江阜丰生物科技有限公司 | 利用菌体蛋白制备赖氨酸发酵培养基的方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| DK134570B (da) | 1976-11-29 |
| CA995163A (en) | 1976-08-17 |
| DE2321461A1 (de) | 1973-11-08 |
| CS182785B2 (en) | 1978-05-31 |
| AU5463773A (en) | 1974-10-24 |
| NL175197C (nl) | 1984-10-01 |
| DK134570C (enrdf_load_stackoverflow) | 1977-05-02 |
| CH574501A5 (enrdf_load_stackoverflow) | 1976-04-15 |
| FR2182211B1 (enrdf_load_stackoverflow) | 1976-06-11 |
| SE410978B (sv) | 1979-11-19 |
| DE2321461B2 (de) | 1975-06-19 |
| FR2182211A1 (enrdf_load_stackoverflow) | 1973-12-07 |
| NL175197B (nl) | 1984-05-01 |
| SU526295A3 (ru) | 1976-08-25 |
| NL7305828A (enrdf_load_stackoverflow) | 1973-10-30 |
| BG24960A3 (en) | 1978-06-15 |
| HU172604B (en) | 1977-11-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PE20 | Patent expired after termination of 20 years |
Effective date: 19930426 |